Linda M Pilarski

Publications

• A Novel Method for Sample Delivery and Testing of Whole Blood: Gel Strip PCR for Point of Care (POC) Molecular Diagnostics
  Lab on a Chip. Oct, 2013  |   Pubmed ID: 23966268
• Storing Self-contained Gel Capillary Cassettes for POC Medical Diagnostics
  Lab on a Chip. Oct, 2013  |   Pubmed ID: 23966212
• Frequent Occurrence of Highly Expanded but Unrelated B-cell Clones in Patients with Multiple Myeloma
  PloS One. 2013  |   Pubmed ID: 23724106
• The Systemic Cytokine Environment is Permanently Altered in Multiple Myeloma
  PloS One. 2013  |   Pubmed ID: 23544044
• Aberrant Splicing, Hyaluronan Synthases and Intracellular Hyaluronan As Drivers of Oncogenesis and Potential Drug Targets
  Current Cancer Drug Targets. May, 2013  |   Pubmed ID: 23517594
• An Enclosed In-gel PCR Amplification Cassette with Multi-target, Multi-sample Detection for Platform Molecular Diagnostics
  Lab on a Chip. Jul, 2013  |   Pubmed ID: 23471315
• Differential Nuclear Organization of Translocation-prone Genes in Nonmalignant B Cells from Patients with T(14;16) As Compared with T(4;14) or T(11;14) Myeloma
  Genes, Chromosomes & Cancer. Jun, 2013  |   Pubmed ID: 23460268
• Alteration of Introns in a Hyaluronan Synthase 1 (HAS1) Minigene Convert Pre-mRNA [corrected] Splicing to the Aberrant Pattern in Multiple Myeloma (MM): MM Patients Harbor Similar Changes
  PloS One. 2013  |   Pubmed ID: 23301075
• In Non-transplant Patients with Multiple Myeloma, the Pre-treatment Level of Clonotypic Cells Predicts Event-free Survival
  Molecular Cancer. 2012  |   Pubmed ID: 23083101
• In Multiple Myeloma, Bone-marrow Lymphocytes Harboring the Same Chromosomal Abnormalities As Autologous Plasma Cells Predict Poor Survival
  American Journal of Hematology. Jun, 2012  |   Pubmed ID: 22495885
• Differential Positioning and Close Spatial Proximity of Translocation-prone Genes in Nonmalignant B-cells from Multiple Myeloma Patients
  Genes, Chromosomes & Cancer. Aug, 2012  |   Pubmed ID: 22489023
• A Miniaturized and Integrated Gel Post Platform for Multiparameter PCR Detection of Herpes Simplex Viruses from Raw Genital Swabs
  Lab on a Chip. May, 2012  |   Pubmed ID: 22426784
• Expression, Adverse Prognostic Significance and Therapeutic Small Molecule Inhibition of Polo-like Kinase 1 in Multiple Myeloma
  Leukemia Research. Dec, 2011  |   Pubmed ID: 21816470
• In a Patient with Biclonal Waldenstrom Macroglobulinemia Only One Clone Expands in Three-dimensional Culture and Includes Putative Cancer Stem Cells
  Leukemia & Lymphoma. Feb, 2011  |   Pubmed ID: 21133724
• In-gel Technology for PCR Genotyping and Pathogen Detection
  Analytical Chemistry. Oct, 2010  |   Pubmed ID: 20809605
• Multiple Myeloma May Include Microvessel Endothelial Cells of Malignant Origin
  Leukemia & Lymphoma. Apr, 2010  |   Pubmed ID: 20233053
• Promiscuity of Translocation Partners in Multiple Myeloma
  Journal of Cellular Biochemistry. Apr, 2010  |   Pubmed ID: 20127714
• Aberrant Splice Variants of HAS1 (Hyaluronan Synthase 1) Multimerize with and Modulate Normally Spliced HAS1 Protein: a Potential Mechanism Promoting Human Cancer
  The Journal of Biological Chemistry. Jul, 2009  |   Pubmed ID: 19451652
• Genetic Abnormalities in Waldenström's Macroglobulinemia
  Clinical Lymphoma & Myeloma. Mar, 2009  |   Pubmed ID: 19362966
• The Relationships Among Physiologic Variables, Quality of Life, and Fatigue in Patients with Multiple Myeloma
  Oncology Nursing Forum. Mar, 2009  |   Pubmed ID: 19273410
• Altered Expression of Fibronectin and Collagens I and IV in Multiple Myeloma and Monoclonal Gammopathy of Undetermined Significance
  The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Mar, 2009  |   Pubmed ID: 19001640
• Multiple Myeloma Includes Phenotypically Defined Subsets of Clonotypic CD20+ B Cells That Persist During Treatment with Rituximab
  Clinical Medicine. Oncology. 2008  |   Pubmed ID: 21892289
• Strategies for Enhancing the Speed and Integration of Microchip Genetic Amplification
  Electrophoresis. Dec, 2008  |   Pubmed ID: 19053066
• An Integrated Microfluidic Chip for Chromosome Enumeration Using Fluorescence in Situ Hybridization
  Lab on a Chip. Dec, 2008  |   Pubmed ID: 19023479
• Inherited and Acquired Variations in the Hyaluronan Synthase 1 (HAS1) Gene May Contribute to Disease Progression in Multiple Myeloma and Waldenstrom Macroglobulinemia
  Blood. Dec, 2008  |   Pubmed ID: 18815290
• Analysis of Clonotypic Switch Junctions Reveals Multiple Myeloma Originates from a Single Class Switch Event with Ongoing Mutation in the Isotype-switched Progeny
  Blood. Sep, 2008  |   Pubmed ID: 18577707
• A Unique Three-dimensional Model for Evaluating the Impact of Therapy on Multiple Myeloma
  Blood. Oct, 2008  |   Pubmed ID: 18535198
• An Inexpensive and Portable Microchip-based Platform for Integrated RT-PCR and Capillary Electrophoresis
  The Analyst. Mar, 2008  |   Pubmed ID: 18299747
• The Selective Aurora B Kinase Inhibitor AZD1152 is a Potential New Treatment for Multiple Myeloma
  British Journal of Haematology. Feb, 2008  |   Pubmed ID: 18076711
• Establishment of BCWM.1 Cell Line for Waldenström's Macroglobulinemia with Productive in Vivo Engraftment in SCID-hu Mice
  Experimental Hematology. Sep, 2007  |   Pubmed ID: 17761288
• Microfluidic Platform for Single Nucleotide Polymorphism Genotyping of the Thiopurine S-methyltransferase Gene to Evaluate Risk for Adverse Drug Events
  The Journal of Molecular Diagnostics : JMD. Sep, 2007  |   Pubmed ID: 17690215
• Microfluidic Chips for Detecting the T(4;14) Translocation and Monitoring Disease During Treatment Using Reverse Transcriptase-polymerase Chain Reaction Analysis of IgH-MMSET Hybrid Transcripts
  The Journal of Molecular Diagnostics : JMD. Jul, 2007  |   Pubmed ID: 17591936
• Molecular Characterization of Waldenstrom's Macroglobulinemia Reveals Frequent Occurrence of Two B-cell Clones Having Distinct IgH VDJ Sequences
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2007  |   Pubmed ID: 17404080
• Ten Years and Counting: So What Do We Know About T(4;14)(p16;q32) Multiple Myeloma
  Leukemia & Lymphoma. Nov, 2006  |   Pubmed ID: 17107900
• Automated Screening Using Microfluidic Chip-based PCR and Product Detection to Assess Risk of BK Virus-associated Nephropathy in Renal Transplant Recipients
  Electrophoresis. Oct, 2006  |   Pubmed ID: 16960845
• Impaired Class Switch Recombination (CSR) in Waldenstrom Macroglobulinemia (WM) Despite Apparently Normal CSR Machinery
  Blood. Apr, 2006  |   Pubmed ID: 16317092
• SSX Cancer Testis Antigens Are Expressed in Most Multiple Myeloma Patients: Co-expression of SSX1, 2, 4, and 5 Correlates with Adverse Prognosis and High Frequencies of SSX-positive PCs
  Journal of Immunotherapy (Hagerstown, Md. : 1997). Nov-Dec, 2005  |   Pubmed ID: 16224274
• Sensitive Detection Using Microfluidics Technology of Single Cell PCR Products from High and Low Abundance IgH VDJ Templates in Multiple Myeloma
  Journal of Immunological Methods. Oct, 2005  |   Pubmed ID: 16150455
• A Potential Role for Centrosomal Deregulation Within IgH Translocation-positive Myeloma
  Medical Hypotheses. 2005  |   Pubmed ID: 16023302
• Identification of Clonotypic IgH VDJ Sequences in Multiple Myeloma
  Methods in Molecular Medicine. 2005  |   Pubmed ID: 15968099
• Potential Impact of a Single Nucleotide Polymorphism in the Hyaluronan Synthase 1 Gene in Waldenstrom's Macroglobulinemia
  Clinical Lymphoma. Mar, 2005  |   Pubmed ID: 15794859
• Origins of Waldenstrom's Macroglobulinemia: Does It Arise from an Unusual B-cell Precursor?
  Clinical Lymphoma. Mar, 2005  |   Pubmed ID: 15794851
• Intronic Splicing of Hyaluronan Synthase 1 (HAS1): a Biologically Relevant Indicator of Poor Outcome in Multiple Myeloma
  Blood. Jun, 2005  |   Pubmed ID: 15731173
• Hyaluronan and Hyaluronan Synthases: Potential Therapeutic Targets in Cancer
  Current Drug Targets. Cardiovascular & Haematological Disorders. Feb, 2005  |   Pubmed ID: 15720220
• Receptor for Hyaluronan-mediated Motility Correlates with Centrosome Abnormalities in Multiple Myeloma and Maintains Mitotic Integrity
  Cancer Research. Feb, 2005  |   Pubmed ID: 15705883
• Overexpression of Transcripts Originating from the MMSET Locus Characterizes All T(4;14)(p16;q32)-positive Multiple Myeloma Patients
  Blood. May, 2005  |   Pubmed ID: 15677557
• A Combined Dielectrophoresis, Traveling Wave Dielectrophoresis and Electrorotation Microchip for the Manipulation and Characterization of Human Malignant Cells
  Journal of Microbiological Methods. Sep, 2004  |   Pubmed ID: 15279943
• RHAMM Expression and Isoform Balance Predict Aggressive Disease and Poor Survival in Multiple Myeloma
  Blood. Aug, 2004  |   Pubmed ID: 15105292
• Genetics and Cytogenetics of Multiple Myeloma: a Workshop Report
  Cancer Research. Feb, 2004  |   Pubmed ID: 14989251
• Clonotypic IgM V/D/J Sequence Analysis in Waldenstrom Macroglobulinemia Suggests an Unusual B-cell Origin and an Expansion of Polyclonal B Cells in Peripheral Blood
  Blood. Oct, 2004  |   Pubmed ID: 14764523
• Discussion on the Safety of 6-mercaptopurine for Childbearing Patients with Inflammatory Bowel Disease: a Retrospective Cohort Study
  Gastroenterology. Nov, 2003  |   Pubmed ID: 14628819
• RHAMM is a Centrosomal Protein That Interacts with Dynein and Maintains Spindle Pole Stability
  Molecular Biology of the Cell. Jun, 2003  |   Pubmed ID: 12808028
• Improved Resolution with Microchip-based Enhanced Field Inversion Electrophoresis
  Electrophoresis. Jun, 2003  |   Pubmed ID: 12783455
• Abnormal Expression of Hyaluronan Synthases in Patients with Waldenstrom's Macroglobulimenia
  Seminars in Oncology. Apr, 2003  |   Pubmed ID: 12720129
• The Malignant Clone in Waldenstrom's Macroglobulinemia
  Seminars in Oncology. Apr, 2003  |   Pubmed ID: 12720122
• In Multiple Myeloma, T(4;14)(p16;q32) is an Adverse Prognostic Factor Irrespective of FGFR3 Expression
  Blood. Feb, 2003  |   Pubmed ID: 12393535
• Clonotypic Myeloma Cells Able to Xenograft Myeloma to Nonobese Diabetic Severe Combined Immunodeficient Mice Copurify with CD34 (+) Hematopoietic Progenitors
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2002  |   Pubmed ID: 12374689
• CD20-directed Serotherapy in Patients with Multiple Myeloma: Biologic Considerations and Therapeutic Applications
  Journal of Immunotherapy (Hagerstown, Md. : 1997). Jan-Feb, 2002  |   Pubmed ID: 11924912
• Leukemic B Cells Clonally Identical to Myeloma Plasma Cells Are Myelomagenic in NOD/SCID Mice
  Experimental Hematology. Mar, 2002  |   Pubmed ID: 11882359
• Intraclonal Homogeneity of Clonotypic Immunoglobulin M and Diversity of Nonclinical Post-switch Isotypes in Multiple Myeloma: Insights into the Evolution of the Myeloma Clone
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2002  |   Pubmed ID: 11839670