Lorenz Aglas Department of Biosciences University of Salzburg Biography Publications Institution JoVE Articles Lorenz Aglas Basic research aspects: My research activities focuses on understanding the mechanism of allergic sensitization induced by pollen allergens, the induction of immune tolerance, and the molecular/immunological characterization of allergens.Translational research: Development of novel therapeutic approaches for the treatment of (pollen) allergiesMain Research AreasMolecular Biology, Molecular and Cellular Allergology, ImmunologyAllergy diagnosis and treatmentRecombinant molecules and physico-chemical characterizationMimetic peptide characterization Publications IgE-cross-blocking Antibodies to Fagales Following Sublingual Immunotherapy with Recombinant Bet V 1 Allergy. Mar, 2021 | Pubmed ID: 33724487 Ragweed Plants Grown Under Elevated CO Levels Produce Pollen Which Elicit Stronger Allergic Lung Inflammation Allergy. 06, 2021 | Pubmed ID: 33037672 Identification and Physicochemical Characterization of a New Allergen from International Journal of Molecular Sciences. Dec, 2020 | Pubmed ID: 33371317 Induction of Functional Inhibitory IgG Antibodies by a Hypoallergenic Bet V 1 Variant Frontiers in Immunology. Month, 2020 | Pubmed ID: 33013894 Initiating Pollen Sensitization - Complex Source, Complex Mechanisms Clinical and Translational Allergy. Month, 2020 | Pubmed ID: 32884636 Ligand Binding of PR-10 Proteins with a Particular Focus on the Bet V 1 Allergen Family Current Allergy and Asthma Reports. 05, 2020 | Pubmed ID: 32430735 A Hybrid of Two Major Blomia Tropicalis Allergens As an Allergy Vaccine Candidate Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology. Month, | Pubmed ID: 32314444 Defining Biomarkers to Predict Symptoms in Subjects with and Without Allergy Under Natural Pollen Exposure The Journal of Allergy and Clinical Immunology. Month, | Pubmed ID: 32272131 N-terminal Peptide Deletion Influences Immunological and Structural Features of Blo T 5 Allergy. Month, | Pubmed ID: 31916257 TGFβ1 Mimetic Peptide Modulates Immune Response to Grass Pollen Allergens in Mice Allergy. Month, | Pubmed ID: 31750952 Multiple Roles of Bet V 1 Ligands in Allergen Stabilization and Modulation of Endosomal Protease Activity Allergy. Month, | Pubmed ID: 31230350 Effectiveness of Grounded Sleeping on Recovery After Intensive Eccentric Muscle Loading Frontiers in Physiology. Month, | Pubmed ID: 30745882 Does Clinical Outcome of Birch Pollen Immunotherapy Relate to Induction of Blocking Antibodies Preventing IgE from Allergen Binding? A Pilot Study Monitoring Responses During First Year of AIT Clinical and Translational Allergy. Month, | Pubmed ID: 30338052 Context Matters: T2 Polarization Resulting from Pollen Composition and Not from Protein-intrinsic Allergenicity The Journal of Allergy and Clinical Immunology. Month, | Pubmed ID: 29782896 Endolysosomal Protease Susceptibility of Amb a 1 As a Determinant of Allergenicity The Journal of Allergy and Clinical Immunology. Month, | Pubmed ID: 29157946 Two Distinct Conformations in Bet V 2 Determine Its Proteolytic Resistance to Cathepsin S International Journal of Molecular Sciences. Month, | Pubmed ID: 29035299 Humanized Mediator Release Assay as a Read-Out for Allergen Potency Mario Wenger1, Athanasios Bethanis1, Litty Johnson1, Lorenz Aglas1 1Department of Biosciences, University of Salzburg JoVE 62702 Immunology and Infection
Humanized Mediator Release Assay as a Read-Out for Allergen Potency Mario Wenger1, Athanasios Bethanis1, Litty Johnson1, Lorenz Aglas1 1Department of Biosciences, University of Salzburg JoVE 62702 Immunology and Infection