Marc G. Achen

Publications

• Vegf-d Promotes Pulmonary Oedema in Hyperoxic Acute Lung Injury
  The Journal of Pathology. Feb, 2016  |   Pubmed ID: 26924464
• Exploring the Role of Endothelium in the Tumour Response to Anti-angiogenic Therapy
  Biochemical Society Transactions. Dec, 2014  |   Pubmed ID: 25399572
• Lymphangiogenesis and Lymphatic Vessel Remodelling in Cancer
  Nature Reviews. Cancer. Mar, 2014  |   Pubmed ID: 24561443
• Ccbe1 Regulates Vegfc-mediated Induction of Vegfr3 Signaling During Embryonic Lymphangiogenesis
  Development (Cambridge, England). Mar, 2014  |   Pubmed ID: 24523457
• The Proteolytic Activation of Angiogenic and Lymphangiogenic Growth Factors in Cancer--its Potential Relevance for Therapeutics and Diagnostics
  Current Medicinal Chemistry. 2014  |   Pubmed ID: 24350854
• VEGFD Regulates Blood Vascular Development by Modulating SOX18 Activity
  Blood. Feb, 2014  |   Pubmed ID: 24269955
• Arap3 is Dysregulated in a Mouse Model of Hypotrichosis-lymphedema-telangiectasia and Regulates Lymphatic Vascular Development
  Human Molecular Genetics. Mar, 2014  |   Pubmed ID: 24163130
• Tissues in Different Anatomical Sites Can Sculpt and Vary the Tumor Microenvironment to Affect Responses to Therapy
  Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2014  |   Pubmed ID: 24048441
• Lymphovascular and Neural Regulation of Metastasis: Shared Tumour Signalling Pathways and Novel Therapeutic Approaches
  Best Practice & Research. Clinical Anaesthesiology. Dec, 2013  |   Pubmed ID: 24267548
• Signaling for Lymphangiogenesis Via VEGFR-3 is Required for the Early Events of Metastasis
  Clinical & Experimental Metastasis. Aug, 2013  |   Pubmed ID: 23591595
• Vascular Endothelial Growth Factor-d Modulates Caliber and Function of Initial Lymphatics in the Dermis
  The Journal of Investigative Dermatology. Aug, 2013  |   Pubmed ID: 23439394
• The VEGF Signaling Pathway in Cancer: the Road Ahead
  Chinese Journal of Cancer. Jun, 2013  |   Pubmed ID: 23419196
• The Propeptides of VEGF-D Determine Heparin Binding, Receptor Heterodimerization, and Effects on Tumor Biology
  The Journal of Biological Chemistry. Mar, 2013  |   Pubmed ID: 23404505
• Tumor Location and Nature of Lymphatic Vessels Are Key Determinants of Cancer Metastasis
  Clinical & Experimental Metastasis. Mar, 2013  |   Pubmed ID: 23124573
• The Connection Between Lymphangiogenic Signalling and Prostaglandin Biology: a Missing Link in the Metastatic Pathway
  Oncotarget. Aug, 2012  |   Pubmed ID: 23097685
• Remodeling of the Lymphatic Vasculature During Mouse Mammary Gland Morphogenesis is Mediated Via Epithelial-derived Lymphangiogenic Stimuli
  The American Journal of Pathology. Dec, 2012  |   Pubmed ID: 23063660
• Vascular Endothelial Growth Factor-D: Signaling Mechanisms, Biology, and Clinical Relevance
  Growth Factors (Chur, Switzerland). Oct, 2012  |   Pubmed ID: 22817635
• Lymphatic Vessel Density in Primary Melanomas Predicts Sentinel Lymph Node Status and Risk of Metastasis
  Histopathology. Oct, 2012  |   Pubmed ID: 22734806
• VEGF-D Promotes Tumor Metastasis by Regulating Prostaglandins Produced by the Collecting Lymphatic Endothelium
  Cancer Cell. Feb, 2012  |   Pubmed ID: 22340592
• Preparation of Human Vascular Endothelial Growth Factor-D for Structural and Preclinical Therapeutic Studies
  Protein Expression and Purification. Mar, 2012  |   Pubmed ID: 22261343
• A Role for Bone Morphogenetic Protein-4 in Lymph Node Vascular Remodeling and Primary Tumor Growth
  Cancer Research. Oct, 2011  |   Pubmed ID: 21868759
• Proteolytic Processing of Vascular Endothelial Growth Factor-D is Essential for Its Capacity to Promote the Growth and Spread of Cancer
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2011  |   Pubmed ID: 21515745
• The VD1 Neutralizing Antibody to Vascular Endothelial Growth Factor-D: Binding Epitope and Relationship to Receptor Binding
  Journal of Molecular Biology. Apr, 2011  |   Pubmed ID: 21315726
• Targeting Lymphatic Vessel Functions Through Tyrosine Kinases
  Journal of Angiogenesis Research. 2010  |   Pubmed ID: 20698997
• Vascular Endothelial Growth Factor-D Over-expressing Tumor Cells Induce Differential Effects on Uterine Vasculature in a Mouse Model of Endometrial Cancer
  Reproductive Biology and Endocrinology : RB&E. 2010  |   Pubmed ID: 20615255
• From Anti-angiogenesis to Anti-lymphangiogenesis: Emerging Trends in Cancer Therapy
  Lymphatic Research and Biology. 2008  |   Pubmed ID: 19093789
• Sox18 Induces Development of the Lymphatic Vasculature in Mice
  Nature. Dec, 2008  |   Pubmed ID: 18931657
• Targeting Tumor Stroma
  Current Cancer Drug Targets. Sep, 2008  |   Pubmed ID: 18781890
• Molecular Control of Lymphatic Metastasis
  Annals of the New York Academy of Sciences. 2008  |   Pubmed ID: 18519975
• Deletion of Vascular Endothelial Growth Factor C (VEGF-C) and VEGF-D is Not Equivalent to VEGF Receptor 3 Deletion in Mouse Embryos
  Molecular and Cellular Biology. Aug, 2008  |   Pubmed ID: 18519586
• A System for Quantifying the Patterning of the Lymphatic Vasculature
  Growth Factors (Chur, Switzerland). Dec, 2007  |   Pubmed ID: 18365872
• Molecular Pathways for Lymphangiogenesis and Their Role in Human Disease
  Novartis Foundation Symposium. 2007  |   Pubmed ID: 17534064
• Distinct Roles of Vascular Endothelial Growth Factor-D in Lymphangiogenesis and Metastasis
  The American Journal of Pathology. Apr, 2007  |   Pubmed ID: 17392173
• Proprotein Convertases Promote Processing of VEGF-D, a Critical Step for Binding the Angiogenic Receptor VEGFR-2
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2007  |   Pubmed ID: 17242158
• Lymphangiogenic Growth Factor Responsiveness is Modulated by Postnatal Lymphatic Vessel Maturation
  The American Journal of Pathology. Aug, 2006  |   Pubmed ID: 16877368
• Lymphatic Vessels in Cancer Metastasis: Bridging the Gaps
  Carcinogenesis. Sep, 2006  |   Pubmed ID: 16597644
• Tumor Lymphangiogenesis and Metastatic Spread-new Players Begin to Emerge
  International Journal of Cancer. Oct, 2006  |   Pubmed ID: 16557570
• Lymphatic Endothelium: an Important Interactive Surface for Malignant Cells
  Pulmonary Pharmacology & Therapeutics. 2006  |   Pubmed ID: 16286238
• Mechanisms of Lymphangiogenesis: Targets for Blocking the Metastatic Spread of Cancer
  Current Cancer Drug Targets. Dec, 2005  |   Pubmed ID: 16375662
• Vascular Endothelial Growth Factor-D Induces Lymphangiogenesis and Lymphatic Metastasis in Models of Ductal Pancreatic Cancer
  International Journal of Oncology. Sep, 2005  |   Pubmed ID: 16077915
• Vascular Endothelial Growth Factor D is Dispensable for Development of the Lymphatic System
  Molecular and Cellular Biology. Mar, 2005  |   Pubmed ID: 15743836
• Focus on Lymphangiogenesis in Tumor Metastasis
  Cancer Cell. Feb, 2005  |   Pubmed ID: 15710325
• Pathogenesis of Persistent Lymphatic Vessel Hyperplasia in Chronic Airway Inflammation
  The Journal of Clinical Investigation. Feb, 2005  |   Pubmed ID: 15668734
• Lymphangiogenic Growth Factors As Markers of Tumor Metastasis
  APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Jul-Aug, 2004  |   Pubmed ID: 15563315
• Molecular Regulation of the VEGF Family -- Inducers of Angiogenesis and Lymphangiogenesis
  APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Jul-Aug, 2004  |   Pubmed ID: 15563310
• Expression of Vascular Endothelial Growth Factor Receptor-3 by Lymphatic Endothelial Cells is Associated with Lymph Node Metastasis in Prostate Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2004  |   Pubmed ID: 15297417
• Adenoviral Catheter-mediated Intramyocardial Gene Transfer Using the Mature Form of Vascular Endothelial Growth Factor-D Induces Transmural Angiogenesis in Porcine Heart
  Circulation. Mar, 2004  |   Pubmed ID: 14967735
• Angiogenic Responses of Vascular Endothelial Growth Factors in Periadventitial Tissue
  Human Gene Therapy. Oct, 2003  |   Pubmed ID: 14577925
• Vascular Endothelial Growth Factor-D Expression in Human Atherosclerotic Lesions
  Cardiovascular Research. Oct, 2003  |   Pubmed ID: 14553837
• Plasmin Activates the Lymphangiogenic Growth Factors VEGF-C and VEGF-D
  The Journal of Experimental Medicine. Sep, 2003  |   Pubmed ID: 12963694
• Viral Vascular Endothelial Growth Factors Vary Extensively in Amino Acid Sequence, Receptor-binding Specificities, and the Ability to Induce Vascular Permeability Yet Are Uniformly Active Mitogens
  The Journal of Biological Chemistry. Sep, 2003  |   Pubmed ID: 12867434
• VEGF-D is the Strongest Angiogenic and Lymphangiogenic Effector Among VEGFs Delivered into Skeletal Muscle Via Adenoviruses
  Circulation Research. May, 2003  |   Pubmed ID: 12714562
• Regenerating Lizard Tails: a New Model for Investigating Lymphangiogenesis
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2003  |   Pubmed ID: 12514111
• Molecular Control of Lymphangiogenesis
  BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Nov, 2002  |   Pubmed ID: 12386934
• Lymphangiogenesis and Cancer Metastasis
  Nature Reviews. Cancer. Aug, 2002  |   Pubmed ID: 12154350
• The Angiogenic and Lymphangiogenic Factor Vascular Endothelial Growth Factor-D Exhibits a Paracrine Mode of Action in Cancer
  Growth Factors (Chur, Switzerland). Jun, 2002  |   Pubmed ID: 12148568
• The Role of Tumor Lymphangiogenesis in Metastatic Spread
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2002  |   Pubmed ID: 12087053
• Adenovirus Encoding Vascular Endothelial Growth Factor-D Induces Tissue-specific Vascular Patterns in Vivo
  Blood. Jun, 2002  |   Pubmed ID: 12036873
• A Simple and Rapid Method for Genetic Transformation of Lactic Streptococci by Electroporation
  Applied and Environmental Microbiology. Mar, 1988  |   Pubmed ID: 16347576