Mark Levine Molecular and Clinical Nutrition Section, Digestive Diseases Branch National Institute of Diabetes and Digestive and Kidney Diseases Biography Publications Institution JoVE Articles Mark Levine has not added a biography. If you are Mark Levine and would like to personalize this page please email our Author Liaison for assistance. Publications State of the Science: Cancer Complementary and Alternative Medicine Therapeutics Research-NCI Strategic Workshop Highlights of Discussion Report Journal of the National Cancer Institute. Monographs. Nov, 2017 | Pubmed ID: 29140484 The SLC2A14 Gene, Encoding the Novel Glucose/dehydroascorbate Transporter GLUT14, is Associated with Inflammatory Bowel Disease The American Journal of Clinical Nutrition. Dec, 2017 | Pubmed ID: 28971850 Chemical Transport Knockout for Oxidized Vitamin C, Dehydroascorbic Acid, Reveals Its Functions in Vivo EBioMedicine. Sep, 2017 | Pubmed ID: 28851583 Measurements of Red Cell Deformability and Hydration Reflect HbF and HbA2 in Blood from Patients with Sickle Cell Anemia Blood Cells, Molecules & Diseases. Jun, 2017 | Pubmed ID: 28472705 Data Triumph at C Cancer Cell. 04, 2017 | Pubmed ID: 28399404 Breaking Down, Starting Up: Can a Vitamin C-enriched Gelatin Supplement Before Exercise Increase Collagen Synthesis? The American Journal of Clinical Nutrition. Jan, 2017 | Pubmed ID: 28003207 Synergistic Effects of Ascorbate and Sorafenib in Hepatocellular Carcinoma: New Insights into Ascorbate Cytotoxicity Free Radical Biology & Medicine. 06, 2016 | Pubmed ID: 27036367 Vitamin C: the Known and the Unknown and Goldilocks Oral Diseases. Sep, 2016 | Pubmed ID: 26808119 Low Red Blood Cell Vitamin C Concentrations Induce Red Blood Cell Fragility: A Link to Diabetes Via Glucose, Glucose Transporters, and Dehydroascorbic Acid EBioMedicine. Nov, 2015 | Pubmed ID: 26870799 Antitumor Effect of Pharmacologic Ascorbate in the B16 Murine Melanoma Model Free Radical Biology & Medicine. Oct, 2015 | Pubmed ID: 26119785 The Human Sodium-dependent Ascorbic Acid Transporters SLC23A1 and SLC23A2 Do Not Mediate Ascorbic Acid Release in the Proximal Renal Epithelial Cell Physiological Reports. Nov, 2013 | Pubmed ID: 24400138 Parenteral Ascorbate As a Cancer Therapeutic: a Reassessment Based on Pharmacokinetics Antioxidants & Redox Signaling. Dec, 2013 | Pubmed ID: 23621620 Ascorbic Acid Kills Epstein-Barr Virus Positive Burkitt Lymphoma Cells and Epstein-Barr Virus Transformed B-cells in Vitro, but Not in Vivo Leukemia & Lymphoma. May, 2013 | Pubmed ID: 23067008 Vitamin C in Mouse and Human Red Blood Cells: an HPLC Assay Analytical Biochemistry. Jul, 2012 | Pubmed ID: 22522059 Phase I Evaluation of Intravenous Ascorbic Acid in Combination with Gemcitabine and Erlotinib in Patients with Metastatic Pancreatic Cancer PloS One. 2012 | Pubmed ID: 22272248 Measurement of Plasma Volume Using Fluorescent Silica-based Nanoparticles Journal of Applied Physiology (Bethesda, Md. : 1985). Feb, 2012 | Pubmed ID: 22174395 Vitamin C: a Concentration-function Approach Yields Pharmacology and Therapeutic Discoveries Advances in Nutrition (Bethesda, Md.). Mar, 2011 | Pubmed ID: 22332036 Pharmacologic Ascorbate Synergizes with Gemcitabine in Preclinical Models of Pancreatic Cancer Free Radical Biology & Medicine. Jun, 2011 | Pubmed ID: 21402145 Vitamin C: Intravenous Use by Complementary and Alternative Medicine Practitioners and Adverse Effects PloS One. Jul, 2010 | Pubmed ID: 20628650 Vitamin C Transporter Slc23a1 Links Renal Reabsorption, Vitamin C Tissue Accumulation, and Perinatal Survival in Mice The Journal of Clinical Investigation. Apr, 2010 | Pubmed ID: 20200446 Major Contribution of Tubular Secretion to Creatinine Clearance in Mice Kidney International. Mar, 2010 | Pubmed ID: 20032962 Losing and Finding a Way at C: New Promise for Pharmacologic Ascorbate in Cancer Treatment Free Radical Biology & Medicine. Jul, 2009 | Pubmed ID: 19361554 Oxalic Acid Excretion After Intravenous Ascorbic Acid Administration Metabolism: Clinical and Experimental. Feb, 2009 | Pubmed ID: 19154961 Genetic Variation in Sodium-dependent Vitamin C Transporters SLC23A1 and SLC23A2 and Risk of Advanced Colorectal Adenoma Nutrition and Cancer. 2008 | Pubmed ID: 18791929 Pharmacologic Doses of Ascorbate Act As a Prooxidant and Decrease Growth of Aggressive Tumor Xenografts in Mice Proceedings of the National Academy of Sciences of the United States of America. Aug, 2008 | Pubmed ID: 18678913 Hypoxia-inducible Factor-1alpha Stabilization in Nonhypoxic Conditions: Role of Oxidation and Intracellular Ascorbate Depletion Molecular Biology of the Cell. Jan, 2008 | Pubmed ID: 17942596 Genomic and Functional Analysis of the Sodium-dependent Vitamin C Transporter SLC23A1-SVCT1 Genes & Nutrition. Oct, 2007 | Pubmed ID: 18850166 Human Adrenal Glands Secrete Vitamin C in Response to Adrenocorticotrophic Hormone The American Journal of Clinical Nutrition. Jul, 2007 | Pubmed ID: 17616774 Ascorbate in Pharmacologic Concentrations Selectively Generates Ascorbate Radical and Hydrogen Peroxide in Extracellular Fluid in Vivo Proceedings of the National Academy of Sciences of the United States of America. May, 2007 | Pubmed ID: 17502596 Inhibition of the Intestinal Glucose Transporter GLUT2 by Flavonoids FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2007 | Pubmed ID: 17172639 Intravenously Administered Vitamin C As Cancer Therapy: Three Cases CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. Mar, 2006 | Pubmed ID: 16567755 Pharmacologic Ascorbic Acid Concentrations Selectively Kill Cancer Cells: Action As a Pro-drug to Deliver Hydrogen Peroxide to Tissues Proceedings of the National Academy of Sciences of the United States of America. Sep, 2005 | Pubmed ID: 16157892 Comparison of the Genomic Structure and Variation in the Two Human Sodium-dependent Vitamin C Transporters, SLC23A1 and SLC23A2 Human Genetics. Sep, 2004 | Pubmed ID: 15316768 Vitamin C Pharmacokinetics: Implications for Oral and Intravenous Use Annals of Internal Medicine. Apr, 2004 | Pubmed ID: 15068981 Vitamin C As an Antioxidant: Evaluation of Its Role in Disease Prevention Journal of the American College of Nutrition. Feb, 2003 | Pubmed ID: 12569111 Cloning and Functional Characterization of the Mouse Fructose Transporter, GLUT5 Biochimica Et Biophysica Acta. Jun, 2002 | Pubmed ID: 12031501 A New Recommended Dietary Allowance of Vitamin C for Healthy Young Women Proceedings of the National Academy of Sciences of the United States of America. Aug, 2001 | Pubmed ID: 11504949 New Insights into the Physiology and Pharmacology of Vitamin C CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. Feb, 2001 | Pubmed ID: 11232136 Ascorbate Recycling in Human Neutrophils: Induction by Bacteria Proceedings of the National Academy of Sciences of the United States of America. Dec, 1997 | Pubmed ID: 9391110 Ektacytometry 血中红细胞异质性的测定 Nermi L. Parrow*1, Pierre-Christian Violet*2, Hongbin Tu2, James Nichols3, Corinne A. Pittman4, Courtney Fitzhugh4, Robert E. Fleming1,5, Narla Mohandas6, John F. Tisdale3, Mark Levine2 1Department of Pediatrics, Saint Louis University School of Medicine, 2Molecular and Clinical Nutrition Section, Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, 3Molecular and Clinical Hematology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, 4Sickle Cell Branch, National Heart, Lung and Blood Institute, National Institutes of Health, 5Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, 6Red Cell Physiology Laboratory, New York Blood Center JoVE 56910 Immunology and Infection
Ektacytometry 血中红细胞异质性的测定 Nermi L. Parrow*1, Pierre-Christian Violet*2, Hongbin Tu2, James Nichols3, Corinne A. Pittman4, Courtney Fitzhugh4, Robert E. Fleming1,5, Narla Mohandas6, John F. Tisdale3, Mark Levine2 1Department of Pediatrics, Saint Louis University School of Medicine, 2Molecular and Clinical Nutrition Section, Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, 3Molecular and Clinical Hematology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, 4Sickle Cell Branch, National Heart, Lung and Blood Institute, National Institutes of Health, 5Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, 6Red Cell Physiology Laboratory, New York Blood Center JoVE 56910 Immunology and Infection