Matthew Merritt Advanced Imaging Research Center University of Texas Southwestern Medical Center Biography Publications Institution JoVE Articles Matthew Merritt has not added a biography. If you are Matthew Merritt and would like to personalize this page please email our Author Liaison for assistance. Publications A General Chemical Shift Decomposition Method for Hyperpolarized (13) C Metabolite Magnetic Resonance Imaging Magnetic Resonance in Chemistry : MRC. Apr, 2016 | Pubmed ID: 27060361 Mitochondrial Metabolism Mediates Oxidative Stress and Inflammation in Fatty Liver The Journal of Clinical Investigation. Apr, 2016 | Pubmed ID: 27035816 Multiband Spectral-spatial RF Excitation for Hyperpolarized [2-(13) C]dihydroxyacetone (13) C-MR Metabolism Studies Magnetic Resonance in Medicine. Mar, 2016 | Pubmed ID: 27017966 Metabolism of Hyperpolarized [1-(13) C]pyruvate Through Alternate Pathways in Rat Liver NMR in Biomedicine. Apr, 2016 | Pubmed ID: 26836042 Mitochondrial Metabolism Mediates Oxidative Stress and Inflammation in Fatty Liver The Journal of Clinical Investigation. Dec, 2015 | Pubmed ID: 26571396 Production of Hyperpolarized (13)CO2 from [1-(13)C]pyruvate in Perfused Liver Does Reflect Total Anaplerosis but is Not a Reliable Biomarker of Glucose Production Metabolomics : Official Journal of the Metabolomic Society. Oct, 2015 | Pubmed ID: 26543443 Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-13C]-Pyruvate Offers Improved Metabolic Imaging of Tumors Cancer Research. Nov, 2015 | Pubmed ID: 26420214 Hyperpolarized (13)C Magnetic Resonance and Its Use in Metabolic Assessment of Cultured Cells and Perfused Organs Methods in Enzymology. 2015 | Pubmed ID: 26358902 Hyperpolarized 13C NMR Detects Rapid Drug-induced Changes in Cardiac Metabolism Magnetic Resonance in Medicine. Aug, 2015 | Pubmed ID: 25168480 Development and Performance of a 129-GHz Dynamic Nuclear Polarizer in an Ultra-wide Bore Superconducting Magnet Magma (New York, N.Y.). Apr, 2015 | Pubmed ID: 25120071 Glutamine Oxidation Maintains the TCA Cycle and Cell Survival During Impaired Mitochondrial Pyruvate Transport Molecular Cell. Nov, 2014 | Pubmed ID: 25458842 Hyperpolarized Magnetic Resonance As a Sensitive Detector of Metabolic Function Biochemistry. Dec, 2014 | Pubmed ID: 25369537 Real-time Detection of Hepatic Gluconeogenic and Glycogenolytic States Using Hyperpolarized [2-13C]dihydroxyacetone The Journal of Biological Chemistry. Dec, 2014 | Pubmed ID: 25352600 Propionate Stimulates Pyruvate Oxidation in the Presence of Acetate American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2014 | Pubmed ID: 25320331 Metabolic Characteristics of Human Hearts Preserved for 12 Hours by Static Storage, Antegrade Perfusion, or Retrograde Coronary Sinus Perfusion The Journal of Thoracic and Cardiovascular Surgery. Nov, 2014 | Pubmed ID: 24642559 Simultaneous Steady-state and Dynamic 13C NMR Can Differentiate Alternative Routes of Pyruvate Metabolism in Living Cancer Cells The Journal of Biological Chemistry. Feb, 2014 | Pubmed ID: 24415759 Electron Spin Resonance Studies of Trityl OX063 at a Concentration Optimal for DNP Physical Chemistry Chemical Physics : PCCP. Jun, 2013 | Pubmed ID: 23676994 Influence of Deuteration in the Glassing Matrix on 13C Dynamic Nuclear Polarization Physical Chemistry Chemical Physics : PCCP. May, 2013 | Pubmed ID: 23552448 Dissolution DNP-NMR Spectroscopy Using Galvinoxyl As a Polarizing Agent Journal of Magnetic Resonance (San Diego, Calif. : 1997). Feb, 2013 | Pubmed ID: 23246650 The Efficiency of DPPH As a Polarising Agent for DNP-NMR Spectroscopy RSC Advances. Jan, 2012 | Pubmed ID: 23205273 Impact of Gd3+ on DNP of [1-13C]pyruvate Doped with Trityl OX063, BDPA, or 4-oxo-TEMPO The Journal of Physical Chemistry. A. May, 2012 | Pubmed ID: 22571288 Comparison of Kinetic Models for Analysis of Pyruvate-to-lactate Exchange by Hyperpolarized 13 C NMR NMR in Biomedicine. Nov, 2012 | Pubmed ID: 22451442 Nanoparticle-based PARACEST Agents: the Quenching Effect of Silica Nanoparticles on the CEST Signal from Surface-conjugated Chelates Contrast Media & Molecular Imaging. Jan-Feb, 2012 | Pubmed ID: 22344876 Production and NMR Characterization of Hyperpolarized (107,109)Ag Complexes Angewandte Chemie (International Ed. in English). Jan, 2012 | Pubmed ID: 21998014 Glucose is an Ineffective Substrate for Preservation of Machine Perfused Donor Hearts The Journal of Surgical Research. Apr, 2012 | Pubmed ID: 21816432 Flux Through Hepatic Pyruvate Carboxylase and Phosphoenolpyruvate Carboxykinase Detected by Hyperpolarized 13C Magnetic Resonance Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 22065779 Differences in Regional Myocardial Perfusion, Metabolism, MVO2, and Edema After Coronary Sinus Machine Perfusion Preservation of Canine Hearts ASAIO Journal (American Society for Artificial Internal Organs : 1992). Nov-Dec, 2011 | Pubmed ID: 22036719 Transfer of Hyperpolarization from Long T1 Storage Nuclei to Short T1 Neighbors Using FLOPSY-8 Journal of Magnetic Resonance (San Diego, Calif. : 1997). Dec, 2011 | Pubmed ID: 21974998 BDPA: an Efficient Polarizing Agent for Fast Dissolution Dynamic Nuclear Polarization NMR Spectroscopy Chemistry (Weinheim an Der Bergstrasse, Germany). Sep, 2011 | Pubmed ID: 21919088 Could 13C MRI Assist Clinical Decision-making for Patients with Heart Disease? NMR in Biomedicine. Oct, 2011 | Pubmed ID: 21608058 T2 Exchange Agents: a New Class of Paramagnetic MRI Contrast Agent That Shortens Water T2 by Chemical Exchange Rather Than Relaxation Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Dec, 2011 | Pubmed ID: 21608031 DNP by Thermal Mixing Under Optimized Conditions Yields >60,000-fold Enhancement of 89Y NMR Signal Journal of the American Chemical Society. Jun, 2011 | Pubmed ID: 21539398 1H Magic Angle Spinning Magnetic Resonance Spectroscopy for Monitoring Machine-perfused Canine Donor Heart Preservation Prior to Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jun, 2011 | Pubmed ID: 21429765 The Effect of 13C Enrichment in the Glassing Matrix on Dynamic Nuclear Polarization of [1-13C]pyruvate Physics in Medicine and Biology. Mar, 2011 | Pubmed ID: 21285486 Competition of Pyruvate with Physiological Substrates for Oxidation by the Heart: Implications for Studies with Hyperpolarized [1-13C]pyruvate American Journal of Physiology. Heart and Circulatory Physiology. May, 2010 | Pubmed ID: 20207817 Hyperpolarized 89Y Complexes As PH Sensitive NMR Probes Journal of the American Chemical Society. Feb, 2010 | Pubmed ID: 20102196 Inhibition of Carbohydrate Oxidation During the First Minute of Reperfusion After Brief Ischemia: NMR Detection of Hyperpolarized 13CO2 and H13CO3- Magnetic Resonance in Medicine. Nov, 2008 | Pubmed ID: 18956454 Alterations in Hepatic Glucose and Energy Metabolism As a Result of Calorie and Carbohydrate Restriction Hepatology (Baltimore, Md.). Nov, 2008 | Pubmed ID: 18925642 Sources of Hepatic Glucose Production by 2H2O Ingestion and Bayesian Analysis of 2H Glucuronide Enrichment Magnetic Resonance in Medicine. Sep, 2008 | Pubmed ID: 18727053 Partial Resistance to Peroxisome Proliferator-activated Receptor-alpha Agonists in ZDF Rats is Associated with Defective Hepatic Mitochondrial Metabolism Diabetes. Aug, 2008 | Pubmed ID: 18469201 Perfusion Preservation Versus Static Preservation for Cardiac Transplantation: Effects on Myocardial Function and Metabolism The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jan, 2008 | Pubmed ID: 18187093 Hyperpolarized 13C Allows a Direct Measure of Flux Through a Single Enzyme-catalyzed Step by NMR Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007 | Pubmed ID: 18056642 Dipolar Cross-relaxation Modulates Signal Amplitudes in the (1)H NMR Spectrum of Hyperpolarized [(13)C]formate Journal of Magnetic Resonance (San Diego, Calif. : 1997). Dec, 2007 | Pubmed ID: 17945520 Hyperpolarized (89)Y Offers the Potential of Direct Imaging of Metal Ions in Biological Systems by Magnetic Resonance Journal of the American Chemical Society. Oct, 2007 | Pubmed ID: 17927188 Benefits of Perfusion Preservation in Canine Hearts Stored for Short Intervals The Journal of Surgical Research. Jun, 2007 | Pubmed ID: 17509270 Hepatic UDP-glucose 13C Isotopomers from [U-13C]glucose: a Simple Analysis by 13C NMR of Urinary Menthol Glucuronide Magnetic Resonance in Medicine. Nov, 2006 | Pubmed ID: 17036288 Lien Entre Les Communications Cellulaires, De L'utilisation De L'énergie Et La Prolifération Métastatique Cancers Neuroendocrines Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16895983 Storage and Oxidation of Long-chain Fatty Acids in the C57/BL6 Mouse Heart As Measured by NMR Spectroscopy FEBS Letters. Jul, 2006 | Pubmed ID: 16831433 Roman Approche De RMN 1 H D'oxymétrie Quantitative De Tissu à L'aide De Hexaméthyldisiloxane Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Apr, 2006 | Pubmed ID: 16506157 Adiabatic JHSQC for 13C Isotopomer Analysis Magnetic Resonance in Chemistry : MRC. Apr, 2006 | Pubmed ID: 16408316 Effects of Insulin and Cytosolic Redox State on Glucose Production Pathways in the Isolated Perfused Mouse Liver Measured by Integrated 2H and 13C NMR The Biochemical Journal. Mar, 2006 | Pubmed ID: 16288601 A New Class of Macrocyclic Lanthanide Complexes for Cell Labeling and Magnetic Resonance Imaging Applications Journal of the American Chemical Society. Nov, 2005 | Pubmed ID: 16287307 Comparison of [3,4-13C2]glucose to [6,6-2H2]glucose As a Tracer for Glucose Turnover by Nuclear Magnetic Resonance Magnetic Resonance in Medicine. Jun, 2005 | Pubmed ID: 15906303 Numerical Solution of the Bloch Equations Provides Insights into the Optimum Design of PARACEST Agents for MRI Magnetic Resonance in Medicine. Apr, 2005 | Pubmed ID: 15799055 Effect of Murine Strain on Metabolic Pathways of Glucose Production After Brief or Prolonged Fasting American Journal of Physiology. Endocrinology and Metabolism. Jul, 2005 | Pubmed ID: 15797985 Differing Mechanisms of Hepatic Glucose Overproduction in Triiodothyronine-treated Rats Vs. Zucker Diabetic Fatty Rats by NMR Analysis of Plasma Glucose American Journal of Physiology. Endocrinology and Metabolism. Apr, 2005 | Pubmed ID: 15562253 Impaired Tricarboxylic Acid Cycle Activity in Mouse Livers Lacking Cytosolic Phosphoenolpyruvate Carboxykinase The Journal of Biological Chemistry. Nov, 2004 | Pubmed ID: 15347677 Glucose Production Pathways by 2H and 13C NMR in Patients with HIV-associated Lipoatrophy Magnetic Resonance in Medicine. Apr, 2004 | Pubmed ID: 15065235 Glucose Production, Gluconeogenesis, and Hepatic Tricarboxylic Acid Cycle Fluxes Measured by Nuclear Magnetic Resonance Analysis of a Single Glucose Derivative Analytical Biochemistry. Apr, 2004 | Pubmed ID: 15051530 Silencing of Phosphonate-gadolinium Magnetic Resonance Imaging Contrast by Hydroxyapatite Binding Investigative Radiology. Dec, 2003 | Pubmed ID: 14627892 PARACEST Agents: Modulating MRI Contrast Via Water Proton Exchange Accounts of Chemical Research. Oct, 2003 | Pubmed ID: 14567712 Sources of Plasma Glucose by Automated Bayesian Analysis of 2H NMR Spectra Magnetic Resonance in Medicine. Oct, 2003 | Pubmed ID: 14523948 Noninvasive Evaluation of Liver Metabolism by 2H and 13C NMR Isotopomer Analysis of Human Urine Analytical Biochemistry. Jan, 2003 | Pubmed ID: 12531210 Utilisation d'un multi-compartiment dynamique unique Enzyme Phantom pour les études de hyperpolarisé Agents de résonance magnétique Christopher M. Walker1, Matthew Merritt2, Jian-Xiong Wang2, James A. Bankson1 1Imaging Physics, University of Texas M.D. Anderson Cancer Center, 2Advanced Imaging Research Center, University of Texas Southwestern Medical Center Engineering
Utilisation d'un multi-compartiment dynamique unique Enzyme Phantom pour les études de hyperpolarisé Agents de résonance magnétique Christopher M. Walker1, Matthew Merritt2, Jian-Xiong Wang2, James A. Bankson1 1Imaging Physics, University of Texas M.D. Anderson Cancer Center, 2Advanced Imaging Research Center, University of Texas Southwestern Medical Center Engineering