Megan N. McClean Department of Biomedical Engineering University of Wisconsin-Madison Biography Publications Institution JoVE Articles Megan N. McClean has not added a biography. If you are Megan N. McClean and would like to personalize this page please email our Author Liaison for assistance. Publications Lustro: High-Throughput Optogenetic Experiments Enabled by Automation and a Yeast Optogenetic Toolkit ACS Synthetic Biology. Jul, 2023 | Pubmed ID: 37434272 Transcription Factor Localization Dynamics and DNA Binding Drive Distinct Promoter Interpretations Cell Reports. May, 2023 | Pubmed ID: 37087734 Strain-dependent Differences in Coordination of Yeast Signalling Networks The FEBS Journal. Apr, 2023 | Pubmed ID: 36416575 Modeling Single-cell Phenotypes Links Yeast Stress Acclimation to Transcriptional Repression and Pre-stress Cellular States ELife. Nov, 2022 | Pubmed ID: 36350693 Cellular Context Alters EGF-induced ERK Dynamics and Reveals Potential Crosstalk with GDF-15 Biomicrofluidics. Sep, 2022 | Pubmed ID: 36217350 Give and Take in the Exometabolome Nature Microbiology. Apr, 2022 | Pubmed ID: 35314782 Design and Implementation of a Microfluidic Device Capable of Temporal Growth Factor Delivery Reveal Filtering Capabilities of the EGFR/ERK Pathway APL Bioengineering. Dec, 2021 | Pubmed ID: 34765858 Optogenetic Tools for Control of Public Goods in Saccharomyces Cerevisiae MSphere. Aug, 2021 | Pubmed ID: 34431694 on Molecular Communication Proceedings of the 7th ACM International Conference on Nanoscale Computing and Communication : Virtual Conference, September 23-25, 2020 : NanoCom 2020. ACM International Conference on Nanoscale Computing and Communication (7th : 2020 :.... Sep, 2020 | Pubmed ID: 35425948 Automated Calibration of OptoPlate LEDs to Reduce Light Dose Variation in Optogenetic Experiments BioTechniques. Oct, 2020 | Pubmed ID: 32722938 Secrete to Beat the Heat Nature Microbiology. Jul, 2020 | Pubmed ID: 32587374 Under Oil Open-channel Microfluidics Empowered by Exclusive Liquid Repellency Science Advances. Apr, 2020 | Pubmed ID: 32494607 A Microfluidic Device for Imaging Samples from Microbial Suspension Cultures MethodsX. 2020 | Pubmed ID: 32420047 A Yeast Optogenetic Toolkit (yOTK) for Gene Expression Control in Saccharomyces Cerevisiae Biotechnology and Bioengineering. Mar, 2020 | Pubmed ID: 31788779 Optogenetic Repressors of Gene Expression in Yeasts Using Light-Controlled Nuclear Localization Cellular and Molecular Bioengineering. Oct, 2019 | Pubmed ID: 31719930 Biological Signal Generators: Integrating Synthetic Biology Tools and Control Current Opinion in Systems Biology. Apr, 2019 | Pubmed ID: 31673669 Easy Calibration of the Light Plate Apparatus for Optogenetic Experiments MethodsX. 2019 | Pubmed ID: 31293905 Single-cell RNA Sequencing Reveals Intrinsic and Extrinsic Regulatory Heterogeneity in Yeast Responding to Stress PLoS Biology. Dec, 2017 | Pubmed ID: 29240790 Engineered Bacteria Self-organize to Sense Pressure Nature Biotechnology. Nov, 2017 | Pubmed ID: 28991269 Robust Network Structure of the Sln1-Ypd1-Ssk1 Three-component Phospho-relay Prevents Unintended Activation of the HOG MAPK Pathway in Saccharomyces Cerevisiae BMC Systems Biology. Mar, 2015 | Pubmed ID: 25888817 Microfluidic Platforms for Generating Dynamic Environmental Perturbations to Study the Responses of Single Yeast Cells Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 25213242 Real-time Optogenetic Control of Intracellular Protein Concentration in Microbial Cell Cultures Integrative Biology : Quantitative Biosciences from Nano to Macro. Mar, 2014 | Pubmed ID: 24477515 Noise and Interlocking Signaling Pathways Promote Distinct Transcription Factor Dynamics in Response to Different Stresses Molecular Biology of the Cell. Jun, 2013 | Pubmed ID: 23615444 Fast-acting and Nearly Gratuitous Induction of Gene Expression and Protein Depletion in Saccharomyces Cerevisiae Molecular Biology of the Cell. Nov, 2011 | Pubmed ID: 21965290 Measuring in Vivo Signaling Kinetics in a Mitogen-activated Kinase Pathway Using Dynamic Input Stimulation Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21468987 In Vivo Measurement of Signaling Cascade Dynamics Cell Cycle (Georgetown, Tex.). Feb, 2009 | Pubmed ID: 19177008 Signal Processing by the HOG MAP Kinase Pathway Proceedings of the National Academy of Sciences of the United States of America. May, 2008 | Pubmed ID: 18480263 Cross-talk and Decision Making in MAP Kinase Pathways Nature Genetics. Mar, 2007 | Pubmed ID: 17259986 Advancing Optogenetics Research Using Lustro (Video) | JoVE Zachary P. Harmer1, Megan N. McClean1,2 1Department of Biomedical Engineering, University of Wisconsin-Madison, 2University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health JoVE 65686 Bioengineering
Advancing Optogenetics Research Using Lustro (Video) | JoVE Zachary P. Harmer1, Megan N. McClean1,2 1Department of Biomedical Engineering, University of Wisconsin-Madison, 2University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health JoVE 65686 Bioengineering