Michael D. Henry Department of Molecular Physiology and Biophysics, Carver College of Medicine University of Iowa Biography Publications Institution JoVE Articles Michael D. Henry has not added a biography. If you are Michael D. Henry and would like to personalize this page please email our Author Liaison for assistance. Publications Melanoma Brain Metastases in the Era of Targeted Therapy and Checkpoint Inhibitor Therapy Cancers. Mar, 2021 | Pubmed ID: 33804910 Pharmacological Ascorbate Inhibits Pancreatic Cancer Metastases Via a Peroxide-mediated Mechanism Scientific Reports. 10, 2020 | Pubmed ID: 33077776 Locally Invasive, Castrate-resistant Prostate Cancer in a Pten/Trp53 Double Knockout Mouse Model of Prostate Cancer Monitored with Non-invasive Bioluminescent Imaging PloS One. 2020 | Pubmed ID: 32986721 Survival of the Resilient: Mechano-adaptation of Circulating Tumor Cells to Fluid Shear Stress Molecular & Cellular Oncology. 2020 | Pubmed ID: 32944626 Functional Genomic Screening Independently Identifies CUL3 As a Mediator of Vemurafenib Resistance Via Src-Rac1 Signaling Axis Frontiers in Oncology. 2020 | Pubmed ID: 32346533 Cancer Cells Resist Mechanical Destruction in Circulation Via RhoA/Actomyosin-Dependent Mechano-Adaptation Cell Reports. 03, 2020 | Pubmed ID: 32187555 Alpha-dystroglycan Staining Pattern and Mortality in Patients Undergoing Radical Prostatectomy with Lymph Node Positive Prostate Cancer The Canadian Journal of Urology. Dec, 2019 | Pubmed ID: 31860423 High Content Screening Identifies Monensin As an EMT-selective Cytotoxic Compound Scientific Reports. 02, 2019 | Pubmed ID: 30718715 Prostate Tumor Cell Exosomes Containing Hyaluronidase Hyal1 Stimulate Prostate Stromal Cell Motility by Engagement of FAK-mediated Integrin Signaling Matrix Biology : Journal of the International Society for Matrix Biology. 05, 2019 | Pubmed ID: 29753676 A Model for the Detection of Pancreatic Ductal Adenocarcinoma Circulating Tumor Cells Journal of Biological Methods. 2018 | Pubmed ID: 31453247 Biomechanics of the Circulating Tumor Cell Microenvironment Advances in Experimental Medicine and Biology. 2018 | Pubmed ID: 30368755 A Trp53fl/flPtenfl/fl Mouse Model of Undifferentiated Pleomorphic Sarcoma Mediated by Adeno-Cre Injection and in Vivo Bioluminescence Imaging PloS One. 2017 | Pubmed ID: 28841687 Natural Products Discovered in a High-Throughput Screen Identified As Inhibitors of RGS17 and As Cytostatic and Cytotoxic Agents for Lung and Prostate Cancer Cell Lines Journal of Natural Products. 07, 2017 | Pubmed ID: 28621943 Inhibiting G Protein βγ Signaling Blocks Prostate Cancer Progression and Enhances the Efficacy of Paclitaxel Oncotarget. May, 2017 | Pubmed ID: 28415604 α3β1 Integrin Suppresses Prostate Cancer Metastasis Via Regulation of the Hippo Pathway Cancer Research. 11, 2016 | Pubmed ID: 27680681 Individualization of Adjuvant Therapy After Radical Prostatectomy for Clinically Localized Prostate Cancer: Current Status and Future Directions Clinical Genitourinary Cancer. Feb, 2016 | Pubmed ID: 26341039 CD151 Promotes α3β1 Integrin-dependent Organization of Carcinoma Cell Junctions and Restrains Collective Cell Invasion Cancer Biology & Therapy. 2015 | Pubmed ID: 26418968 Downregulation of Dystroglycan Glycosyltransferases LARGE2 and ISPD Associate with Increased Mortality in Clear Cell Renal Cell Carcinoma Molecular Cancer. Jul, 2015 | Pubmed ID: 26220087 Targeting Geranylgeranylation Reduces Adrenal Gland Tumor Burden in a Murine Model of Prostate Cancer Metastasis Clinical & Experimental Metastasis. Aug, 2015 | Pubmed ID: 26070429 Alterations in Cancer Cell Mechanical Properties After Fluid Shear Stress Exposure: a Micropipette Aspiration Study Cell Health and Cytoskeleton. Jan, 2015 | Pubmed ID: 25908902 Loss of SOD3 (EcSOD) Expression Promotes an Aggressive Phenotype in Human Pancreatic Ductal Adenocarcinoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2015 | Pubmed ID: 25634994 The Glycosyltransferase LARGE2 is Repressed by Snail and ZEB1 in Prostate Cancer Cancer Biology & Therapy. 2015 | Pubmed ID: 25455932 Transcriptome-wide Landscape of Pre-mRNA Alternative Splicing Associated with Metastatic Colonization Molecular Cancer Research : MCR. Feb, 2015 | Pubmed ID: 25274489 RMATS: Robust and Flexible Detection of Differential Alternative Splicing from Replicate RNA-Seq Data Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25480548 Impact of Prostate Inflammation on Lesion Development in the POET3(+)Pten(+/-) Mouse Model of Prostate Carcinogenesis The American Journal of Pathology. Dec, 2014 | Pubmed ID: 25455686 Integrin α3β1 Can Function to Promote Spontaneous Metastasis and Lung Colonization of Invasive Breast Carcinoma Molecular Cancer Research : MCR. Jan, 2014 | Pubmed ID: 24002891 Prolyl-4-hydroxylase 3 (PHD3) Expression is Downregulated During Epithelial-to-mesenchymal Transition PloS One. 2013 | Pubmed ID: 24367580 Chronic Chlorpyrifos Exposure Does Not Promote Prostate Cancer in Prostate Specific PTEN Mutant Mice Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society for Environmental Toxicology and Cancer. 2013 | Pubmed ID: 23758150 Integrin α3β1 Regulates Tumor Cell Responses to Stromal Cells and Can Function to Suppress Prostate Cancer Metastatic Colonization Clinical & Experimental Metastasis. Apr, 2013 | Pubmed ID: 23224938 Loss of LARGE2 Disrupts Functional Glycosylation of α-dystroglycan in Prostate Cancer The Journal of Biological Chemistry. Jan, 2013 | Pubmed ID: 23223448 Resistance to Fluid Shear Stress is a Conserved Biophysical Property of Malignant Cells PloS One. 2012 | Pubmed ID: 23226552 Eradication of Metastatic Renal Cell Carcinoma After Adenovirus-encoded TNF-related Apoptosis-inducing Ligand (TRAIL)/CpG Immunotherapy PloS One. 2012 | Pubmed ID: 22312440 Slow Disease Progression in a C57BL/6 Pten-deficient Mouse Model of Prostate Cancer The American Journal of Pathology. Jul, 2011 | Pubmed ID: 21703427 Epithelial-to-mesenchymal Transition in Prostate Cancer: Paradigm or Puzzle? Nature Reviews. Urology. Jun, 2011 | Pubmed ID: 21691304 An Inducible Model of Abacterial Prostatitis Induces Antigen Specific Inflammatory and Proliferative Changes in the Murine Prostate The Prostate. Aug, 2011 | Pubmed ID: 21656824 The ARF Tumor Suppressor Inhibits Tumor Cell Colonization Independent of P53 in a Novel Mouse Model of Pancreatic Ductal Adenocarcinoma Metastasis Molecular Cancer Research : MCR. Jul, 2011 | Pubmed ID: 21636682 ZEB1 Coordinately Regulates Laminin-332 and {beta}4 Integrin Expression Altering the Invasive Phenotype of Prostate Cancer Cells The Journal of Biological Chemistry. Oct, 2010 | Pubmed ID: 20729552 Bone-specific Growth Inhibition of Prostate Cancer Metastasis by Atrasentan Cancer Biology & Therapy. Apr, 2010 | Pubmed ID: 20139704 Dystroglycan is Not Required for Maintenance of the Luminal Epithelial Basement Membrane or Cell Polarity in the Mouse Prostate The Prostate. May, 2010 | Pubmed ID: 20054819 Loss of Alpha-dystroglycan Laminin Binding in Epithelium-derived Cancers is Caused by Silencing of LARGE The Journal of Biological Chemistry. Apr, 2009 | Pubmed ID: 19244252 Endothelin-1 Inhibits Prostate Cancer Growth in Vivo Through Vasoconstriction of Tumor-feeding Arterioles Cancer Biology & Therapy. Apr, 2009 | Pubmed ID: 19242129 ZEB1 Enhances Transendothelial Migration and Represses the Epithelial Phenotype of Prostate Cancer Cells Molecular Biology of the Cell. Apr, 2009 | Pubmed ID: 19225155 Assessing SiRNA Pharmacodynamics in a Luciferase-expressing Mouse Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2008 | Pubmed ID: 18781145 Chemotherapeutic Agents Up-regulate the Cytomegalovirus Promoter: Implications for Bioluminescence Imaging of Tumor Response to Therapy Cancer Research. Nov, 2007 | Pubmed ID: 17974988 Dystroglycan Loss Disrupts Polarity and Beta-casein Induction in Mammary Epithelial Cells by Perturbing Laminin Anchoring Journal of Cell Science. Oct, 2006 | Pubmed ID: 16968749 Assessing Tumor Growth and Distribution in a Model of Prostate Cancer Metastasis Using Bioluminescence Imaging Clinical & Experimental Metastasis. 2005 | Pubmed ID: 16703413 Disruption of Perlecan Binding and Matrix Assembly by Post-translational or Genetic Disruption of Dystroglycan Function FEBS Letters. Aug, 2005 | Pubmed ID: 16098969 Spiculated Periosteal Response Induced by Intraosseous Injection of 22Rv1 Prostate Cancer Cells Resembles Subset of Bone Metastases in Prostate Cancer Patients The Prostate. Dec, 2005 | Pubmed ID: 16032708 Unique Role of Dystroglycan in Peripheral Nerve Myelination, Nodal Structure, and Sodium Channel Stabilization Neuron. Jun, 2003 | Pubmed ID: 12797959 Deletion of Brain Dystroglycan Recapitulates Aspects of Congenital Muscular Dystrophy Nature. Jul, 2002 | Pubmed ID: 12140559 Dystroglycan is Selectively Associated with Inhibitory GABAergic Synapses but is Dispensable for Their Differentiation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2002 | Pubmed ID: 12040032 Dystroglycan Inside and Out Current Opinion in Cell Biology. Oct, 1999 | Pubmed ID: 10508656 Dystroglycan: an Extracellular Matrix Receptor Linked to the Cytoskeleton Current Opinion in Cell Biology. Oct, 1996 | Pubmed ID: 8939660 Modellering av effekterna av hemodynamisk stress på cirkulerande tumörceller med en spruta och nål Devon L. Moose1,2, Sophia Williams-Perez3, Renee Cafun1, Benjamin L. Krog1, Michael D. Henry1,2,4,5,6 1Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, 2Holden Comprehensive Cancer Center, University of Iowa, 3MD program, Carver College of Medicine, University of Iowa, 4Department of Pathology, Carver College of Medicine, University of Iowa, 5Department of Urology, Carver College of Medicine, University of Iowa, 6Department of Radiation Oncology, Carver College of Medicine, University of Iowa JoVE 62478 Cancer Research
Modellering av effekterna av hemodynamisk stress på cirkulerande tumörceller med en spruta och nål Devon L. Moose1,2, Sophia Williams-Perez3, Renee Cafun1, Benjamin L. Krog1, Michael D. Henry1,2,4,5,6 1Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, 2Holden Comprehensive Cancer Center, University of Iowa, 3MD program, Carver College of Medicine, University of Iowa, 4Department of Pathology, Carver College of Medicine, University of Iowa, 5Department of Urology, Carver College of Medicine, University of Iowa, 6Department of Radiation Oncology, Carver College of Medicine, University of Iowa JoVE 62478 Cancer Research