Michael Caligiuri Department of Psychiatry University of California, San Diego Biography Publications Institution JoVE Articles Michael Caligiuri has not added a biography. If you are Michael Caligiuri and would like to personalize this page please email our Author Liaison for assistance. Publications Eradicating Acute Myeloid Leukemia in a MllPTD/wt:Flt3ITD/wt Murine Model: a Path to Novel Therapeutic Approaches for Human Disease Blood. Oct, 2013 | Pubmed ID: 24085765 Location and Cellular Stages of Natural Killer Cell Development Trends in Immunology. Sep, 2013 | Pubmed ID: 24055329 PP2A-activating Drugs Selectively Eradicate TKI-resistant Chronic Myeloid Leukemic Stem Cells The Journal of Clinical Investigation. Oct, 2013 | Pubmed ID: 23999433 Preclinical and Clinical Efficacy of XPO1/CRM1 Inhibition by the Karyopherin Inhibitor KPT-330 in Ph+ Leukemias Blood. Oct, 2013 | Pubmed ID: 23970380 Modafinil Improves Antipsychotic-induced Parkinsonism but Not Excessive Daytime Sleepiness, Psychiatric Symptoms or Cognition in Schizophrenia and Schizoaffective Disorder: a Randomized, Double-blind, Placebo-controlled Study Schizophrenia Research. Oct, 2013 | Pubmed ID: 23938173 Antagonistic Activities of the Immunomodulator and PP2A-activating Drug FTY720 (Fingolimod, Gilenya) in Jak2-driven Hematologic Malignancies Blood. Sep, 2013 | Pubmed ID: 23926298 Ibrutinib is an Irreversible Molecular Inhibitor of ITK Driving a Th1-selective Pressure in T Lymphocytes Blood. Oct, 2013 | Pubmed ID: 23886836 In Rare Acute Myeloid Leukemia Patients Harboring Both RUNX1 and NPM1 Mutations, RUNX1 Mutations Are Unusual in Structure and Present in the Germline Haematologica. Aug, 2013 | Pubmed ID: 23753029 Uncovering a Novel Mechanism Whereby NK Cells Interfere with Glioblastoma Virotherapy Oncoimmunology. Apr, 2013 | Pubmed ID: 23734319 Axl/Gas6 Pathway Positively Regulates FLT3 Activation in Human Natural Killer Cell Development European Journal of Immunology. Oct, 2013 | Pubmed ID: 23722894 Clinical Role of MicroRNAs in Cytogenetically Normal Acute Myeloid Leukemia: MiR-155 Upregulation Independently Identifies High-risk Patients Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2013 | Pubmed ID: 23650424 MicroRNAs Activate Natural Killer Cells Through Toll-like Receptor Signaling Blood. Jun, 2013 | Pubmed ID: 23580661 Silvestrol Exhibits Significant in Vivo and in Vitro Antileukemic Activities and Inhibits FLT3 and MiR-155 Expressions in Acute Myeloid Leukemia Journal of Hematology & Oncology. 2013 | Pubmed ID: 23497456 Targeted Delivery of MicroRNA-29b by Transferrin-conjugated Anionic Lipopolyplex Nanoparticles: a Novel Therapeutic Strategy in Acute Myeloid Leukemia Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2013 | Pubmed ID: 23493348 Overexpression of MiR-155 Causes Expansion, Arrest in Terminal Differentiation and Functional Activation of Mouse Natural Killer Cells Blood. Apr, 2013 | Pubmed ID: 23422749 Comparative Assessment of Clinically Utilized CD20-directed Antibodies in Chronic Lymphocytic Leukemia Cells Reveals Divergent NK Cell, Monocyte, and Macrophage Properties Journal of Immunology (Baltimore, Md. : 1950). Mar, 2013 | Pubmed ID: 23418626 Identification of a 24-gene Prognostic Signature That Improves the European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: an International Collaborative Study Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2013 | Pubmed ID: 23382473 Inhibition of the Receptor Tyrosine Kinase Axl Impedes Activation of the FLT3 Internal Tandem Duplication in Human Acute Myeloid Leukemia: Implications for Axl As a Potential Therapeutic Target Blood. Mar, 2013 | Pubmed ID: 23321254 Epigenetic Silencing of MicroRNA-193a Contributes to Leukemogenesis in T(8;21) Acute Myeloid Leukemia by Activating the PTEN/PI3K Signal Pathway Blood. Jan, 2013 | Pubmed ID: 23223432 Inv(16)/t(16;16) Acute Myeloid Leukemia with Non-type A CBFB-MYH11 Fusions Associate with Distinct Clinical and Genetic Features and Lack KIT Mutations Blood. Jan, 2013 | Pubmed ID: 23160462 Lenalidomide-mediated Enhanced Translation of C/EBPα-p30 Protein Up-regulates Expression of the Antileukemic MicroRNA-181a in Acute Myeloid Leukemia Blood. Jan, 2013 | Pubmed ID: 23100311 Quantitative Assessment of Motor Abnormalities in Untreated Patients with Major Depressive Disorder Journal of Affective Disorders. Mar, 2013 | Pubmed ID: 22985485 NK Cells Impede Glioblastoma Virotherapy Through NKp30 and NKp46 Natural Cytotoxicity Receptors Nature Medicine. Dec, 2012 | Pubmed ID: 23178246 Aberrant Overexpression of IL-15 Initiates Large Granular Lymphocyte Leukemia Through Chromosomal Instability and DNA Hypermethylation Cancer Cell. Nov, 2012 | Pubmed ID: 23153537 Nonadherence to the Isochrony Principle in Forged Signatures Forensic Science International. Nov, 2012 | Pubmed ID: 23084659 A Phase 1 Trial of the Anti-KIR Antibody IPH2101 in Patients with Relapsed/refractory Multiple Myeloma Blood. Nov, 2012 | Pubmed ID: 23033266 Essential Metabolic, Anti-inflammatory, and Anti-tumorigenic Functions of MiR-122 in Liver The Journal of Clinical Investigation. Aug, 2012 | Pubmed ID: 22820288 Genome-wide Methylation Profiling in Decitabine-treated Patients with Acute Myeloid Leukemia Blood. Sep, 2012 | Pubmed ID: 22786882 RUNX1 Mutations Are Associated with Poor Outcome in Younger and Older Patients with Cytogenetically Normal Acute Myeloid Leukemia and with Distinct Gene and MicroRNA Expression Signatures Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Sep, 2012 | Pubmed ID: 22753902 MicroRNAs Bind to Toll-like Receptors to Induce Prometastatic Inflammatory Response Proceedings of the National Academy of Sciences of the United States of America. Jul, 2012 | Pubmed ID: 22753494 Stress Hematopoiesis Reveals Abnormal Control of Self-renewal, Lineage Bias, and Myeloid Differentiation in Mll Partial Tandem Duplication (Mll-PTD) Hematopoietic Stem/progenitor Cells Blood. Aug, 2012 | Pubmed ID: 22740449 Preclinical Activity of a Novel CRM1 Inhibitor in Acute Myeloid Leukemia Blood. Aug, 2012 | Pubmed ID: 22677130 Mll Partial Tandem Duplication and Flt3 Internal Tandem Duplication in a Double Knock-in Mouse Recapitulates Features of Counterpart Human Acute Myeloid Leukemias Blood. Aug, 2012 | Pubmed ID: 22674806 Clinical and Pharmacodynamic Activity of Bortezomib and Decitabine in Acute Myeloid Leukemia Blood. Jun, 2012 | Pubmed ID: 22566605 MiR-3151 Interplays with Its Host Gene BAALC and Independently Affects Outcome of Patients with Cytogenetically Normal Acute Myeloid Leukemia Blood. Jul, 2012 | Pubmed ID: 22529287 Regulation of Acute Graft-versus-host Disease by MicroRNA-155 Blood. Mar, 2012 | Pubmed ID: 22408260 MiR-155 Regulates IFN-γ Production in Natural Killer Cells Blood. Feb, 2012 | Pubmed ID: 22378844 Evidence for a Stepwise Program of Extrathymic T Cell Development Within the Human Tonsil The Journal of Clinical Investigation. Apr, 2012 | Pubmed ID: 22378041 The HDAC Inhibitor Valproic Acid Lessens NK Cell Action Against Oncolytic Virus-infected Glioblastoma Cells with Inhibition of STAT5/T-BET Signaling and IFNγ Generation Journal of Virology. Feb, 2012 | Pubmed ID: 22318143 Deciphering the Multifaceted Relationship Between Oncolytic Viruses and Natural Killer Cells Advances in Virology. 2012 | Pubmed ID: 22312364 Age-related Prognostic Impact of Different Types of DNMT3A Mutations in Adults with Primary Cytogenetically Normal Acute Myeloid Leukemia Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2012 | Pubmed ID: 22291079 Extracellular Matrix Protein CCN1 Limits Oncolytic Efficacy in Glioma Cancer Research. Mar, 2012 | Pubmed ID: 22282654 Up-regulation of a HOXA-PBX3 Homeobox-gene Signature Following Down-regulation of MiR-181 is Associated with Adverse Prognosis in Patients with Cytogenetically Abnormal AML Blood. Mar, 2012 | Pubmed ID: 22251480 Targeted Immunotherapy for Acute Myeloid Leukemia Best Practice & Research. Clinical Haematology. Dec, 2011 | Pubmed ID: 22127317 ASXL1 Mutations Identify a High-risk Subgroup of Older Patients with Primary Cytogenetically Normal AML Within the ELN Favorable Genetic Category Blood. Dec, 2011 | Pubmed ID: 22031865 IPH2101, a Novel Anti-inhibitory KIR Antibody, and Lenalidomide Combine to Enhance the Natural Killer Cell Versus Multiple Myeloma Effect Blood. Dec, 2011 | Pubmed ID: 22031859 Voxel-based Morphometry of Patients with Schizophrenia or Bipolar I Disorder: a Matched Control Study Psychiatry Research. Nov, 2011 | Pubmed ID: 21924872 Low Expression of MN1 Associates with Better Treatment Response in Older Patients with De Novo Cytogenetically Normal Acute Myeloid Leukemia Blood. Oct, 2011 | Pubmed ID: 21828125 Associations Between Spontaneous Movement Abnormalities and Psychotic-like Experiences in the General Population Schizophrenia Research. Nov, 2011 | Pubmed ID: 21782390 LyGDI, a Novel SHIP-interacting Protein, is a Negative Regulator of FcγR-mediated Phagocytosis PloS One. 2011 | Pubmed ID: 21695085 Clinical Outcome and Gene- and MicroRNA-expression Profiling According to the Wilms Tumor 1 (WT1) Single Nucleotide Polymorphism Rs16754 in Adult De Novo Cytogenetically Normal Acute Myeloid Leukemia: a Cancer and Leukemia Group B Study Haematologica. Oct, 2011 | Pubmed ID: 21659357 The Large Zinc Finger Protein ZAS3 is a Critical Modulator of Osteoclastogenesis PloS One. 2011 | Pubmed ID: 21390242 NKp46 Identifies an NKT Cell Subset Susceptible to Leukemic Transformation in Mouse and Human The Journal of Clinical Investigation. Apr, 2011 | Pubmed ID: 21364281 TET2 Mutations Improve the New European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: a Cancer and Leukemia Group B Study Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Apr, 2011 | Pubmed ID: 21343549 A Sheep in Wolf's Clothing Blood. Feb, 2011 | Pubmed ID: 21292781 IκBζ Augments IL-12- and IL-18-mediated IFN-γ Production in Human NK Cells Blood. Mar, 2011 | Pubmed ID: 21224476 Innate or Adaptive Immunity? The Example of Natural Killer Cells Science (New York, N.Y.). Jan, 2011 | Pubmed ID: 21212348 The PP2A Inhibitor SET Regulates Granzyme B Expression in Human Natural Killer Cells Blood. Feb, 2011 | Pubmed ID: 21156847 The Dynamic Character of Disguise Behavior for Text-based, Mixed, and Stylized Signatures Journal of Forensic Sciences. Jan, 2011 | Pubmed ID: 20950317 Prognostic Significance of Expression of a Single MicroRNA, MiR-181a, in Cytogenetically Normal Acute Myeloid Leukemia: a Cancer and Leukemia Group B Study Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2010 | Pubmed ID: 21079133 PRDM1/Blimp-1 Controls Effector Cytokine Production in Human NK Cells Journal of Immunology (Baltimore, Md. : 1950). Nov, 2010 | Pubmed ID: 20944005 BAALC and ERG Expression Levels Are Associated with Outcome and Distinct Gene and MicroRNA Expression Profiles in Older Patients with De Novo Cytogenetically Normal Acute Myeloid Leukemia: a Cancer and Leukemia Group B Study Blood. Dec, 2010 | Pubmed ID: 20841507 Immature NK Cells, Capable of Producing IL-22, Are Present in Human Uterine Mucosa Journal of Immunology (Baltimore, Md. : 1950). Oct, 2010 | Pubmed ID: 20802153 FLT3 Internal Tandem Duplication Associates with Adverse Outcome and Gene- and MicroRNA-expression Signatures in Patients 60 Years of Age or Older with Primary Cytogenetically Normal Acute Myeloid Leukemia: a Cancer and Leukemia Group B Study Blood. Nov, 2010 | Pubmed ID: 20656931 Interleukin-1beta Selectively Expands and Sustains Interleukin-22+ Immature Human Natural Killer Cells in Secondary Lymphoid Tissue Immunity. Jun, 2010 | Pubmed ID: 20620944 The PD-1/PD-L1 Axis Modulates the Natural Killer Cell Versus Multiple Myeloma Effect: a Therapeutic Target for CT-011, a Novel Monoclonal Anti-PD-1 Antibody Blood. Sep, 2010 | Pubmed ID: 20460501 Mutations of the Wilms Tumor 1 Gene (WT1) in Older Patients with Primary Cytogenetically Normal Acute Myeloid Leukemia: a Cancer and Leukemia Group B Study Blood. Aug, 2010 | Pubmed ID: 20442368 Sp1/NFkappaB/HDAC/miR-29b Regulatory Network in KIT-driven Myeloid Leukemia Cancer Cell. Apr, 2010 | Pubmed ID: 20385359 Handwriting Movement Kinematics for Quantifying Extrapyramidal Side Effects in Patients Treated with Atypical Antipsychotics Psychiatry Research. May, 2010 | Pubmed ID: 20381875 IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: a Cancer and Leukemia Group B Study Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. May, 2010 | Pubmed ID: 20368543 MiR-328 Functions As an RNA Decoy to Modulate HnRNP E2 Regulation of MRNA Translation in Leukemic Blasts Cell. Mar, 2010 | Pubmed ID: 20211135 In Vivo Role of Flt3 Ligand and Dendritic Cells in NK Cell Homeostasis Journal of Immunology (Baltimore, Md. : 1950). Mar, 2010 | Pubmed ID: 20142363 Differential Effects of IL-2 and IL-21 on Expansion of the CD4+ CD25+ Foxp3+ T Regulatory Cells with Redundant Roles in Natural Killer Cell Mediated Antibody Dependent Cellular Cytotoxicity in Chronic Lymphocytic Leukemia MAbs. Jan-Feb, 2010 | Pubmed ID: 20081380 Purification of Human NK Cell Developmental Intermediates from Lymph Nodes and Tonsils Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20033630 Favorable Prognostic Impact of NPM1 Mutations in Older Patients with Cytogenetically Normal De Novo Acute Myeloid Leukemia and Associated Gene- and MicroRNA-expression Signatures: a Cancer and Leukemia Group B Study Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Feb, 2010 | Pubmed ID: 20026798 CD19 Targeting of Chronic Lymphocytic Leukemia with a Novel Fc-domain-engineered Monoclonal Antibody Blood. Feb, 2010 | Pubmed ID: 19965644 CD94 Surface Density Identifies a Functional Intermediary Between the CD56bright and CD56dim Human NK-cell Subsets Blood. Jan, 2010 | Pubmed ID: 19897577 A Novel Mouse Model for the Aggressive Variant of NK Cell and T Cell Large Granular Lymphocyte Leukemia Leukemia Research. Feb, 2010 | Pubmed ID: 19660811 CD94 Defines Phenotypically and Functionally Distinct Mouse NK Cell Subsets Journal of Immunology (Baltimore, Md. : 1950). Oct, 2009 | Pubmed ID: 19801519 Handwriting Movement Analyses for Monitoring Drug-induced Motor Side Effects in Schizophrenia Patients Treated with Risperidone Human Movement Science. Oct, 2009 | Pubmed ID: 19692133 Preclinical Characterization of 1-7F9, a Novel Human Anti-KIR Receptor Therapeutic Antibody That Augments Natural Killer-mediated Killing of Tumor Cells Blood. Sep, 2009 | Pubmed ID: 19553639 Prognostic Importance of MN1 Transcript Levels, and Biologic Insights from MN1-associated Gene and MicroRNA Expression Signatures in Cytogenetically Normal Acute Myeloid Leukemia: a Cancer and Leukemia Group B Study Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jul, 2009 | Pubmed ID: 19451432 Reformed Consent: Adapting to New Media and Research Participant Preferences IRB. Mar-Apr, 2009 | Pubmed ID: 19402337 TSC-22 Contributes to Hematopoietic Precursor Cell Proliferation and Repopulation and is Epigenetically Silenced in Large Granular Lymphocyte Leukemia Blood. May, 2009 | Pubmed ID: 19329776 Stage 3 Immature Human Natural Killer Cells Found in Secondary Lymphoid Tissue Constitutively and Selectively Express the TH 17 Cytokine Interleukin-22 Blood. Apr, 2009 | Pubmed ID: 19244159 The Humanized CD40 Antibody SGN-40 Demonstrates Pre-clinical Activity That is Enhanced by Lenalidomide in Chronic Lymphocytic Leukaemia British Journal of Haematology. Mar, 2009 | Pubmed ID: 19183192 Stem Cell Factor and Interleukin-2/15 Combine to Enhance MAPK-mediated Proliferation of Human Natural Killer Cells Blood. Mar, 2009 | Pubmed ID: 19060242 A Phase II Trial of Trastuzumab in Combination with Low-dose Interleukin-2 (IL-2) in Patients (PTS) with Metastatic Breast Cancer (MBC) Who Have Previously Failed Trastuzumab Breast Cancer Research and Treatment. Sep, 2009 | Pubmed ID: 19051009 The Axl/Gas6 Pathway is Required for Optimal Cytokine Signaling During Human Natural Killer Cell Development Blood. Mar, 2009 | Pubmed ID: 18840707 Prognostic Significance Of, and Gene and MicroRNA Expression Signatures Associated With, CEBPA Mutations in Cytogenetically Normal Acute Myeloid Leukemia with High-risk Molecular Features: a Cancer and Leukemia Group B Study Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Nov, 2008 | Pubmed ID: 18809607 Tumor Growth Decreases NK and B Cells As Well As Common Lymphoid Progenitor PloS One. 2008 | Pubmed ID: 18784839 Natural Killer Cells in Innate Immunity and Cancer Journal of Immunotherapy (Hagerstown, Md. : 1997). Oct, 2008 | Pubmed ID: 18779751 TGF-beta Utilizes SMAD3 to Inhibit CD16-mediated IFN-gamma Production and Antibody-dependent Cellular Cytotoxicity in Human NK Cells Journal of Immunology (Baltimore, Md. : 1950). Sep, 2008 | Pubmed ID: 18768831 Human Natural Killer Cells Blood. Aug, 2008 | Pubmed ID: 18650461 The Mll Partial Tandem Duplication: Differential, Tissue-specific Activity in the Presence or Absence of the Wild-type Allele Blood. Sep, 2008 | Pubmed ID: 18617636 Low-dose Interleukin-2 Immunotherapy Does Not Improve Outcome of Patients Age 60 Years and Older with Acute Myeloid Leukemia in First Complete Remission: Cancer and Leukemia Group B Study 9720 Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2008 | Pubmed ID: 18591543 DNA Hypermethylation and Epigenetic Silencing of the Tumor Suppressor Gene, SLC5A8, in Acute Myeloid Leukemia with the MLL Partial Tandem Duplication Blood. Sep, 2008 | Pubmed ID: 18566324 Wilms' Tumor 1 Gene Mutations Independently Predict Poor Outcome in Adults with Cytogenetically Normal Acute Myeloid Leukemia: a Cancer and Leukemia Group B Study Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2008 | Pubmed ID: 18559874 MicroRNA Expression in Cytogenetically Normal Acute Myeloid Leukemia The New England Journal of Medicine. May, 2008 | Pubmed ID: 18450603 A Novel Raji-Burkitt's Lymphoma Model for Preclinical and Mechanistic Evaluation of CD52-targeted Immunotherapeutic Agents Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2008 | Pubmed ID: 18223233 Reduction in Neuroleptic-induced Movement Disorders After a Switch to Quetiapine in Patients with Schizophrenia Journal of Clinical Psychopharmacology. Feb, 2008 | Pubmed ID: 18204344 IL-21 Mediates Apoptosis Through Up-regulation of the BH3 Family Member BIM and Enhances Both Direct and Antibody-dependent Cellular Cytotoxicity in Primary Chronic Lymphocytic Leukemia Cells in Vitro Blood. May, 2008 | Pubmed ID: 18182577 Colocalization of the IL-12 Receptor and FcgammaRIIIa to Natural Killer Cell Lipid Rafts Leads to Activation of ERK and Enhanced Production of Interferon-gamma Blood. Apr, 2008 | Pubmed ID: 18174382 Bortezomib Induces DNA Hypomethylation and Silenced Gene Transcription by Interfering with Sp1/NF-kappaB-dependent DNA Methyltransferase Activity in Acute Myeloid Leukemia Blood. Feb, 2008 | Pubmed ID: 18083845 SOS1 Mutations Are Rare in Human Malignancies: Implications for Noonan Syndrome Patients Genes, Chromosomes & Cancer. Mar, 2008 | Pubmed ID: 18064648 FLT3 D835/I836 Mutations Are Associated with Poor Disease-free Survival and a Distinct Gene-expression Signature Among Younger Adults with De Novo Cytogenetically Normal Acute Myeloid Leukemia Lacking FLT3 Internal Tandem Duplications Blood. Feb, 2008 | Pubmed ID: 17940205 Identification of Novel Posttranscriptional Targets of the BCR/ABL Oncoprotein by Ribonomics: Requirement of E2F3 for BCR/ABL Leukemogenesis Blood. Jan, 2008 | Pubmed ID: 17925491 Specific Tumor Suppressor Function for E2F2 in Myc-induced T Cell Lymphomagenesis Proceedings of the National Academy of Sciences of the United States of America. Sep, 2007 | Pubmed ID: 17881568 The PP2A Inhibitor SET Regulates Natural Killer Cell IFN-gamma Production The Journal of Experimental Medicine. Oct, 2007 | Pubmed ID: 17875674 FTY720, a New Alternative for Treating Blast Crisis Chronic Myelogenous Leukemia and Philadelphia Chromosome-positive Acute Lymphocytic Leukemia The Journal of Clinical Investigation. Sep, 2007 | Pubmed ID: 17717597 Transcriptional Control of Human T-BET Expression: the Role of Sp1 European Journal of Immunology. Sep, 2007 | Pubmed ID: 17705132 Chronic Lymphocytosis of Functionally Immature Natural Killer Cells The Journal of Allergy and Clinical Immunology. Oct, 2007 | Pubmed ID: 17604094 Pharmacologic Inhibition of CDK4/6: Mechanistic Evidence for Selective Activity or Acquired Resistance in Acute Myeloid Leukemia Blood. Sep, 2007 | Pubmed ID: 17537993 Distinct Patterns of Mutations Occurring in De Novo AML Versus AML Arising in the Setting of Severe Congenital Neutropenia Blood. Sep, 2007 | Pubmed ID: 17494858 Novel C-CBL and CBL-b Ubiquitin Ligase Mutations in Human Acute Myeloid Leukemia Blood. Aug, 2007 | Pubmed ID: 17475912 High Levels of the BCR/ABL Oncoprotein Are Required for the MAPK-hnRNP-E2 Dependent Suppression of C/EBPalpha-driven Myeloid Differentiation Blood. Aug, 2007 | Pubmed ID: 17475908 Targeting CD37-positive Lymphoid Malignancies with a Novel Engineered Small Modular Immunopharmaceutical Blood. Oct, 2007 | Pubmed ID: 17440052 Mcl-1 is a Relevant Therapeutic Target in Acute and Chronic Lymphoid Malignancies: Down-regulation Enhances Rituximab-mediated Apoptosis and Complement-dependent Cytotoxicity Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2007 | Pubmed ID: 17404098 Internal Versus External: Oral-motor Performance As a Function of Attentional Focus Journal of Speech, Language, and Hearing Research : JSLHR. Feb, 2007 | Pubmed ID: 17344554 Long-term Disease-free Survivors with Cytogenetically Normal Acute Myeloid Leukemia and MLL Partial Tandem Duplication: a Cancer and Leukemia Group B Study Blood. Jun, 2007 | Pubmed ID: 17341662 Hlx Homeobox Transcription Factor Negatively Regulates Interferon-gamma Production in Monokine-activated Natural Killer Cells Blood. Mar, 2007 | Pubmed ID: 17110450 A Phase 2 Study of Rituximab in Combination with Recombinant Interleukin-2 for Rituximab-refractory Indolent Non-Hodgkin's Lymphoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2006 | Pubmed ID: 17145827 Predictors of Neuroleptic-induced Dyskinesia and Parkinsonism: the Influence of Measurement Methods and Definitions Journal of Clinical Psychopharmacology. Dec, 2006 | Pubmed ID: 17110811 Human Natural Killer Cell Development Immunological Reviews. Dec, 2006 | Pubmed ID: 17100876 Mll Partial Tandem Duplication Induces Aberrant Hox Expression in Vivo Via Specific Epigenetic Alterations The Journal of Clinical Investigation. Oct, 2006 | Pubmed ID: 16981007 Abnormalities in Motor Physiology in Bipolar Disorder The Journal of Neuropsychiatry and Clinical Neurosciences. 2006 | Pubmed ID: 16963583 Cyclophosphamide Enhances Glioma Virotherapy by Inhibiting Innate Immune Responses Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16908838 Phase 1 Clinical Results with Tandutinib (MLN518), a Novel FLT3 Antagonist, in Patients with Acute Myelogenous Leukemia or High-risk Myelodysplastic Syndrome: Safety, Pharmacokinetics, and Pharmacodynamics Blood. Dec, 2006 | Pubmed ID: 16902153 The Effect of KIR Ligand Incompatibility on the Outcome of Unrelated Donor Transplantation: a Report from the Center for International Blood and Marrow Transplant Research, the European Blood and Marrow Transplant Registry, and the Dutch Registry Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Aug, 2006 | Pubmed ID: 16864058 PhenoChipping of Psychotic Disorders: a Novel Approach for Deconstructing and Quantitating Psychiatric Phenotypes American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. Sep, 2006 | Pubmed ID: 16838358 Impaired Hemispheric Communication in Schizophrenia: a Study Using the Consonant-vowel-consonant Task Schizophrenia Research. Oct, 2006 | Pubmed ID: 16822652 A Phase I Study of Ultra Low Dose Interleukin-2 and Stem Cell Factor in Patients with HIV Infection or HIV and Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2006 | Pubmed ID: 16818697 Trans-presentation of Donor-derived Interleukin 15 is Necessary for the Rapid Onset of Acute Graft-versus-host Disease but Not for Graft-versus-tumor Activity Blood. Oct, 2006 | Pubmed ID: 16757683 Cancer and Leukemia Group B Leukemia Correlative Science Committee: Major Accomplishments and Future Directions Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2006 | Pubmed ID: 16740786 Preclinical Assessment of FHIT Gene Replacement Therapy in Human Leukemia Using a Chimeric Adenovirus, Ad5/F35 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2006 | Pubmed ID: 16740775 Pro- and Antiinflammatory Cytokine Signaling: Reciprocal Antagonism Regulates Interferon-gamma Production by Human Natural Killer Cells Immunity. May, 2006 | Pubmed ID: 16713975 Independent Confirmation of a Prognostic Gene-expression Signature in Adult Acute Myeloid Leukemia with a Normal Karyotype: a Cancer and Leukemia Group B Study Blood. Sep, 2006 | Pubmed ID: 16670265 Quantitative Measurement of Handwriting in the Assessment of Drug-induced Parkinsonism Human Movement Science. Oct, 2006 | Pubmed ID: 16647772 Assessment of Tumor Necrosis Factor Alpha Blockade As an Intervention to Improve Tolerability of Dose-intensive Chemotherapy in Cancer Patients Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Apr, 2006 | Pubmed ID: 16622259 Immunologic Approaches to Acute Leukemia in the Elderly Seminars in Hematology. Apr, 2006 | Pubmed ID: 16616045 Evidence for Discrete Stages of Human Natural Killer Cell Differentiation in Vivo The Journal of Experimental Medicine. Apr, 2006 | Pubmed ID: 16606675 Recent Advances in the Treatment of Transplant-related Lymphoma Clinical Advances in Hematology & Oncology : H&O. Jan, 2006 | Pubmed ID: 16562366 Tumor Growth Impedes Natural-killer-cell Maturation in the Bone Marrow Blood. Jul, 2006 | Pubmed ID: 16556890 FcgammaR-induced Production of Superoxide and Inflammatory Cytokines is Differentially Regulated by SHIP Through Its Influence on PI3K And/or Ras/Erk Pathways Blood. Jul, 2006 | Pubmed ID: 16543474 Autologous Immune Strategies to Reduce the Risk of Leukemic Relapse: Consideration for IL-15 Best Practice & Research. Clinical Haematology. 2006 | Pubmed ID: 16516125 Non-Hodgkin's Lymphoma. Clinical Practice Guidelines in Oncology Journal of the National Comprehensive Cancer Network : JNCCN. Mar, 2006 | Pubmed ID: 16507273 Striatopallidal Regulation of Affect in Bipolar Disorder Journal of Affective Disorders. Apr, 2006 | Pubmed ID: 16503055 STAT-1-mediated Repression of Monocyte Interleukin-10 Gene Expression in Vivo European Journal of Immunology. Mar, 2006 | Pubmed ID: 16482512 Pharmacogenetics for Off-patent Antipsychotics: Reframing the Risk for Tardive Dyskinesia and Access to Essential Medicines Expert Opinion on Pharmacotherapy. Feb, 2006 | Pubmed ID: 16433578 Responsiveness of Naive CD4 T Cells to Polarizing Cytokine Determines the Ratio of Th1 and Th2 Cell Differentiation Journal of Immunology (Baltimore, Md. : 1950). Feb, 2006 | Pubmed ID: 16424184 Human Natural Killer Cell Development and Biology Blood Reviews. May, 2006 | Pubmed ID: 16364519 Select High-risk Genetic Features Predict Earlier Progression Following Chemoimmunotherapy with Fludarabine and Rituximab in Chronic Lymphocytic Leukemia: Justification for Risk-adapted Therapy Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jan, 2006 | Pubmed ID: 16344317 EBV-encoded DUTPase Induces Immune Dysregulation: Implications for the Pathophysiology of EBV-associated Disease Virology. Mar, 2006 | Pubmed ID: 16321417 A MAPK/HNRPK Pathway Controls BCR/ABL Oncogenic Potential by Regulating MYC MRNA Translation Blood. Mar, 2006 | Pubmed ID: 16293596 The Tumor Suppressor PP2A is Functionally Inactivated in Blast Crisis CML Through the Inhibitory Activity of the BCR/ABL-regulated SET Protein Cancer Cell. Nov, 2005 | Pubmed ID: 16286244 Overexpression of the ETS-related Gene, ERG, Predicts a Worse Outcome in Acute Myeloid Leukemia with Normal Karyotype: a Cancer and Leukemia Group B Study Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2005 | Pubmed ID: 16275934 Cytokine Therapy for Cancer: Antigen Presentation Cancer Treatment and Research. 2005 | Pubmed ID: 16211874 Src Homology 2-containing Inositol 5'-phosphatase 1 Negatively Regulates IFN-gamma Production by Natural Killer Cells Stimulated with Antibody-coated Tumor Cells and Interleukin-12 Cancer Research. Oct, 2005 | Pubmed ID: 16204085 The BRG1- and HBRM-associated Factor BAF57 Induces Apoptosis by Stimulating Expression of the Cylindromatosis Tumor Suppressor Gene Molecular and Cellular Biology. Sep, 2005 | Pubmed ID: 16135788 Lateralized Cognitive Dysfunction and Psychotic Symptoms in Schizophrenia Schizophrenia Research. Dec, 2005 | Pubmed ID: 16125374 Do Preclinical Findings of Methamphetamine-induced Motor Abnormalities Translate to an Observable Clinical Phenotype? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Dec, 2005 | Pubmed ID: 16123755 Durable Hematologic Complete Response and Suppression of HTLV-1 Viral Load Following Alemtuzumab in Zidovudine/IFN-{alpha}-refractory Adult T-cell Leukemia Blood. Nov, 2005 | Pubmed ID: 16076875 Human CTLA4 Knock-in Mice Unravel the Quantitative Link Between Tumor Immunity and Autoimmunity Induced by Anti-CTLA-4 Antibodies Blood. Nov, 2005 | Pubmed ID: 16037385 IL-15 but Not IL-2 Rapidly Induces Lethal Xenogeneic Graft-versus-host Disease Blood. Oct, 2005 | Pubmed ID: 15976176 Cellular Uptake and Intracellular Levels of the Bcl-2 Antisense G3139 in Cultured Cells and Treated Patients with Acute Myeloid Leukemia Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2005 | Pubmed ID: 15837754 Relationship of Neuromotor Disturbances to Psychosis Symptoms in First-episode Neuroleptic-naive Schizophrenia Patients Schizophrenia Research. Jun, 2005 | Pubmed ID: 15820325 A Human CD34(+) Subset Resides in Lymph Nodes and Differentiates into CD56bright Natural Killer Cells Immunity. Mar, 2005 | Pubmed ID: 15780987 The MLL Partial Tandem Duplication: Evidence for Recessive Gain-of-function in Acute Myeloid Leukemia Identifies a Novel Patient Subgroup for Molecular-targeted Therapy Blood. Jul, 2005 | Pubmed ID: 15774615 Global Assessment of Promoter Methylation in a Mouse Model of Cancer Identifies ID4 As a Putative Tumor-suppressor Gene in Human Leukemia Nature Genetics. Mar, 2005 | Pubmed ID: 15723065 Interleukin-2, Interleukin-15, and Their Roles in Human Natural Killer Cells Advances in Immunology. 2005 | Pubmed ID: 15705423 Efficient Infection of Human Natural Killer Cells with an EBV/retroviral Hybrid Vector Journal of Immunological Methods. Jan, 2005 | Pubmed ID: 15680156 Acute Myeloid Leukemia with Deletion 9q Within a Noncomplex Karyotype is Associated with CEBPA Loss-of-function Mutations Genes, Chromosomes & Cancer. Apr, 2005 | Pubmed ID: 15645492 Differential Expression of SHIP1 in CD56bright and CD56dim NK Cells Provides a Molecular Basis for Distinct Functional Responses to Monokine Costimulation Blood. Apr, 2005 | Pubmed ID: 15604218 IFN-gamma Gene Polymorphisms Associate with Development of EBV+ Lymphoproliferative Disease in Hu PBL-SCID Mice Blood. Feb, 2005 | Pubmed ID: 15498860 Anti-human CTLA-4 Monoclonal Antibody Promotes T-cell Expansion and Immunity in a Hu-PBL-SCID Model: a New Method for Preclinical Screening of Costimulatory Monoclonal Antibodies Blood. Feb, 2005 | Pubmed ID: 15486062 Donor-derived IL-15 is Critical for Acute Allogeneic Graft-versus-host Disease Blood. Jan, 2005 | Pubmed ID: 15374888 Isolation and Characterization of Human Natural Killer Cell Subsets Current Protocols in Immunology / Edited by John E. Coligan ... [et Al.]. May, 2004 | Pubmed ID: 18432933 Immunotherapeutic Approaches for Hematologic Malignancies Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 2004 | Pubmed ID: 15561691 Failed Adoptive Immunotherapy with Tumor-specific T Cells: Reversal with Low-dose Interleukin 15 but Not Low-dose Interleukin 2 Cancer Research. Nov, 2004 | Pubmed ID: 15520217 Dose Escalation Studies of Cytarabine, Daunorubicin, and Etoposide with and Without Multidrug Resistance Modulation with PSC-833 in Untreated Adults with Acute Myeloid Leukemia Younger Than 60 Years: Final Induction Results of Cancer and Leukemia Group B Study 9621 Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Nov, 2004 | Pubmed ID: 15514371 Functional Brain Asymmetries During Visuomotor Tracking Journal of Clinical and Experimental Neuropsychology. May, 2004 | Pubmed ID: 15512926 A NotI-EcoRV Promoter Library for Studies of Genetic and Epigenetic Alterations in Mouse Models of Human Malignancies Genomics. Oct, 2004 | Pubmed ID: 15475242 Selective Efficacy of Depsipeptide in a Xenograft Model of Epstein-Barr Virus-positive Lymphoproliferative Disorder Journal of the National Cancer Institute. Oct, 2004 | Pubmed ID: 15467034 Cytokine Modulation of the Innate Immune System in the Treatment of Leukemia and Lymphoma Advances in Pharmacology (San Diego, Calif.). 2004 | Pubmed ID: 15464915 Combination Immunotherapy of B-cell Non-Hodgkin's Lymphoma with Rituximab and Interleukin-2: a Preclinical and Phase I Study Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2004 | Pubmed ID: 15447996 Association of Diabetes with Dyskinesia in Older Psychosis Patients Psychopharmacology. Nov, 2004 | Pubmed ID: 15138754 Clinical Rating Scales and Instruments: How Do They Compare in Assessing Abnormal, Involuntary Movements? Journal of Clinical Psychopharmacology. Jun, 2004 | Pubmed ID: 15118484 A Functional Magnetic Resonance Imaging Study of Cortical Asymmetry in Bipolar Disorder Bipolar Disorders. Jun, 2004 | Pubmed ID: 15117397 Enhanced Cytotoxicity of Allogeneic NK Cells with Killer Immunoglobulin-like Receptor Ligand Incompatibility Against Melanoma and Renal Cell Carcinoma Cells Blood. Jul, 2004 | Pubmed ID: 15016654 Acute Myeloid Leukemia with Complex Karyotypes and Abnormal Chromosome 21: Amplification Discloses Overexpression of APP, ETS2, and ERG Genes Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 15007164 Prognostic Importance of TLX1 (HOX11) Oncogene Expression in Adults with T-cell Acute Lymphoblastic Leukaemia Lancet. Feb, 2004 | Pubmed ID: 14975618 Loss of C/EBP Alpha and Favorable Prognosis of Acute Myeloid Leukemias: a Biological Paradox Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Feb, 2004 | Pubmed ID: 14726508 NK Cell and DC Interactions Trends in Immunology. Jan, 2004 | Pubmed ID: 14698284 EBV Kidney Allograft Infection: Possible Relationship with a Peri-graft Localization of PTLD American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Jan, 2004 | Pubmed ID: 14678042 AIDS-associated Malignancies Cancer Chemotherapy and Biological Response Modifiers. 2003 | Pubmed ID: 15338771 Rituximab: Converging Mechanisms of Action in Non-Hodgkin's Lymphoma? Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2003 | Pubmed ID: 14676100 A Pilot Study of High-throughput, Sequence-based Mutational Profiling of Primary Human Acute Myeloid Leukemia Cell Genomes Proceedings of the National Academy of Sciences of the United States of America. Nov, 2003 | Pubmed ID: 14614138 A Quantitative Neuromotor Predictor of Antidepressant Non-response in Patients with Major Depression Journal of Affective Disorders. Nov, 2003 | Pubmed ID: 14607390 BAALC, a Novel Marker of Human Hematopoietic Progenitor Cells Experimental Hematology. Nov, 2003 | Pubmed ID: 14585369 The Role of STAT1 in Viral Sensitization to LPS Journal of Endotoxin Research. 2003 | Pubmed ID: 14577848 लिखावट विश्लेषण मानसिकता के लिए उच्च जोखिम में न्यूरोलेप्टिक भोले किशोरों में सहज Dyskinesias इंगित करता है Derek J. Dean1, Hans-Leo Teulings2, Michael Caligiuri3, Vijay A. Mittal1 1Department of Psychology and Neuroscience, Center for Neuroscience, University of Colorado Boulder, 2NeuroScript LLC, 3Department of Psychiatry, University of California, San Diego JoVE 50852 Behavior
लिखावट विश्लेषण मानसिकता के लिए उच्च जोखिम में न्यूरोलेप्टिक भोले किशोरों में सहज Dyskinesias इंगित करता है Derek J. Dean1, Hans-Leo Teulings2, Michael Caligiuri3, Vijay A. Mittal1 1Department of Psychology and Neuroscience, Center for Neuroscience, University of Colorado Boulder, 2NeuroScript LLC, 3Department of Psychiatry, University of California, San Diego JoVE 50852 Behavior
