Michelle L. James

Publications

• Multimodal Imaging of Capsid and Cargo Reveals Differential Brain Targeting and Liver Detargeting of Systemically-administered AAVs
  Biomaterials. Sep, 2022  |   Pubmed ID: 35985893
• ICOS ImmunoPET Enables Visualization of Activated T Cells and Early Diagnosis of Murine Acute Gastrointestinal GvHD
  Blood Advances. Aug, 2022  |   Pubmed ID: 35790103
• Radiosynthesis and Initial Preclinical Evaluation of [C]AZD1283 As a Potential P2Y12R PET Radiotracer
  Nuclear Medicine and Biology. 2022  |   Pubmed ID: 35680502
• Approaches for Addressing Challenges in CNS Radiopharmaceutical Design
  ACS Chemical Neuroscience. Jun, 2022  |   Pubmed ID: 35606334
• Tracking Innate Immune Activation in a Mouse Model of Parkinson's Disease Using TREM1 and TSPO PET Tracers
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Oct, 2022  |   Pubmed ID: 35177426
• Whole-body PET Imaging of T-cell Response to Glioblastoma
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2021  |   Pubmed ID: 34548318
• A Clinical PET Imaging Tracer ([F]DASA-23) to Monitor Pyruvate Kinase M2-Induced Glycolytic Reprogramming in Glioblastoma
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2021  |   Pubmed ID: 34475101
• Hippocampal Subfield Imaging and Fractional Anisotropy Show Parallel Changes in Alzheimer's Disease Tau Progression Using Simultaneous Tau-PET/MRI at 3T
  Alzheimer's & Dementia (Amsterdam, Netherlands). 2021  |   Pubmed ID: 34337132
• On the Consensus Nomenclature Rules for Radiopharmaceutical Chemistry - Reconsideration of Radiochemical Conversion
  Nuclear Medicine and Biology. Feb, 2021  |   Pubmed ID: 33232876
• Development of a CD19 PET Tracer for Detecting B Cells in a Mouse Model of Multiple Sclerosis
  Journal of Neuroinflammation. Sep, 2020  |   Pubmed ID: 32948198
• Histologic Evaluation of Activation of Acute Inflammatory Response in a Mouse Model Following Ultrasound-mediated Blood-brain Barrier Using Different Acoustic Pressures and Microbubble Doses
  Nanotheranostics. 2020  |   Pubmed ID: 32802731
• Simultaneous FDG-PET/MRI Detects Hippocampal Subfield Metabolic Differences in AD/MCI
  Scientific Reports. Jul, 2020  |   Pubmed ID: 32694602
• Training the Next Generation of Radiopharmaceutical Scientists
  Nuclear Medicine and Biology. 2020  |   Pubmed ID: 32650289
• Neuroinflammation PET Imaging: Current Opinion and Future Directions
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Aug, 2020  |   Pubmed ID: 32620705
• Physiological Blood-brain Transport is Impaired with Age by a Shift in Transcytosis
  Nature. Jul, 2020  |   Pubmed ID: 32612231
• Positron Emission Tomography Imaging of Novel AAV Capsids Maps Rapid Brain Accumulation
  Nature Communications. Apr, 2020  |   Pubmed ID: 32355221
• Demarcation of Sepsis-Induced Peripheral and Central Acidosis with PH (Low) Insertion Cycle Peptide
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Sep, 2020  |   Pubmed ID: 32005774
• Peripheral TREM1 Responses to Brain and Intestinal Immunogens Amplify Stroke Severity
  Nature Immunology. Aug, 2019  |   Pubmed ID: 31263278
• Longitudinal Translocator Protein-18 KDa-positron Emission Tomography Imaging of Peripheral and Central Myeloid Cells in a Mouse Model of Complex Regional Pain Syndrome
  Pain. Sep, 2019  |   Pubmed ID: 31095093
• Microglial Modulation As a Target for Chronic Pain: From the Bench to the Bedside and Back
  Anesthesia and Analgesia. 04, 2019  |   Pubmed ID: 30883419
• C-DPA-713 Versus F-GE-180: A Preclinical Comparison of Translocator Protein 18 KDa PET Tracers to Visualize Acute and Chronic Neuroinflammation in a Mouse Model of Ischemic Stroke
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jan, 2019  |   Pubmed ID: 29976695
• Successful Treatment of Chronic Knee Pain Following Localization by a Sigma-1 Receptor Radioligand and PET/MRI: a Case Report
  Journal of Pain Research. 2018  |   Pubmed ID: 30349360
• TSPO-PET Imaging Using [18F]PBR06 is a Potential Translatable Biomarker for Treatment Response in Huntington's Disease: Preclinical Evidence with the P75NTR Ligand LM11A-31
  Human Molecular Genetics. May, 2018  |   Pubmed ID: 29860333
• Imaging Activated T Cells Predicts Response to Cancer Vaccines
  The Journal of Clinical Investigation. Jun, 2018  |   Pubmed ID: 29596062
• [F]FSPG-PET Reveals Increased Cystine/glutamate Antiporter (xc-) Activity in a Mouse Model of Multiple Sclerosis
  Journal of Neuroinflammation. Feb, 2018  |   Pubmed ID: 29471880
• Visualizing Nerve Injury in a Neuropathic Pain Model with [F]FTC-146 PET/MRI
  Theranostics. 2017  |   Pubmed ID: 28824716
• Imaging B Cells in a Mouse Model of Multiple Sclerosis Using Cu-Rituximab PET
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Nov, 2017  |   Pubmed ID: 28687602
• [F]GE-180 PET Detects Reduced Microglia Activation After LM11A-31 Therapy in a Mouse Model of Alzheimer's Disease
  Theranostics. 2017  |   Pubmed ID: 28529627
• Multimodal Assessment of SERS Nanoparticle Biodistribution Post Ingestion Reveals New Potential for Clinical Translation of Raman Imaging
  Biomaterials. Aug, 2017  |   Pubmed ID: 28486147
• Human Umbilical Cord Plasma Proteins Revitalize Hippocampal Function in Aged Mice
  Nature. 04, 2017  |   Pubmed ID: 28424512
• Development of [F]DASA-23 for Imaging Tumor Glycolysis Through Noninvasive Measurement of Pyruvate Kinase M2
  Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Oct, 2017  |   Pubmed ID: 28236227
• PET Imaging of Tumor Glycolysis Downstream of Hexokinase Through Noninvasive Measurement of Pyruvate Kinase M2
  Science Translational Medicine. Oct, 2015  |   Pubmed ID: 26491079
• Microglial Malfunction: the Third Rail in the Development of Alzheimer's Disease
  Trends in Neurosciences. Oct, 2015  |   Pubmed ID: 26442696
• Further Validation to Support Clinical Translation of [(18)F]FTC-146 for Imaging Sigma-1 Receptors
  EJNMMI Research. Dec, 2015  |   Pubmed ID: 26384292
• PET Imaging of Translocator Protein (18 KDa) in a Mouse Model of Alzheimer's Disease Using N-(2,5-dimethoxybenzyl)-2-18F-fluoro-N-(2-phenoxyphenyl)acetamide
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Feb, 2015  |   Pubmed ID: 25613536
• Antiviral Drug Ganciclovir is a Potent Inhibitor of Microglial Proliferation and Neuroinflammation
  The Journal of Experimental Medicine. Feb, 2014  |   Pubmed ID: 24493798
• Evaluation of σ-1 Receptor Radioligand 18F-FTC-146 in Rats and Squirrel Monkeys Using PET
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jan, 2014  |   Pubmed ID: 24337599
• PET Imaging of Stroke-induced Neuroinflammation in Mice Using [18F]PBR06
  Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Feb, 2014  |   Pubmed ID: 23836504
• A 18F-labeled Saxitoxin Derivative for in Vivo PET-MR Imaging of Voltage-gated Sodium Channel Expression Following Nerve Injury
  Journal of the American Chemical Society. Dec, 2013  |   Pubmed ID: 24261833
• Integrin-targeted Molecular Imaging of Experimental Abdominal Aortic Aneurysms by (18)F-labeled Arg-Gly-Asp Positron-emission Tomography
  Circulation. Cardiovascular Imaging. Nov, 2013  |   Pubmed ID: 23995363
• Colony-stimulating Factor 1 Receptor (CSF1R) Signaling in Injured Neurons Facilitates Protection and Survival
  The Journal of Experimental Medicine. Jan, 2013  |   Pubmed ID: 23296467
• New Positron Emission Tomography (PET) Radioligand for Imaging σ-1 Receptors in Living Subjects
  Journal of Medicinal Chemistry. Sep, 2012  |   Pubmed ID: 22853801
• A Molecular Imaging Primer: Modalities, Imaging Agents, and Applications
  Physiological Reviews. Apr, 2012  |   Pubmed ID: 22535898
• Preclinical Evaluation of Raman Nanoparticle Biodistribution for Their Potential Use in Clinical Endoscopy Imaging
  Small (Weinheim an Der Bergstrasse, Germany). Aug, 2011  |   Pubmed ID: 21608124