Mohamed N. Seleem Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine Virginia Polytechnic Institute and State University Biography Publications Institution JoVE Articles Mohamed N. Seleem has not added a biography. If you are Mohamed N. Seleem and would like to personalize this page please email our Author Liaison for assistance. Publications Repurposing FDA-approved Sulphonamide Carbonic Anhydrase Inhibitors for Treatment of Journal of Enzyme Inhibition and Medicinal Chemistry. Dec, 2022 | Pubmed ID: 34894972 Dithiocarbamates Effectively Inhibit the α-carbonic Anhydrase from Journal of Enzyme Inhibition and Medicinal Chemistry. Dec, 2022 | Pubmed ID: 34894954 Flexible Microneedle Array Patch for Chronic Wound Oxygenation and Biofilm Eradication ACS Applied Bio Materials. Jul, 2021 | Pubmed ID: 35006756 Evaluation of Bisphenylthiazoles As a Promising Class for Combating Multidrug-resistant Fungal Infections PloS One. 2021 | Pubmed ID: 34735467 RNA-seq-based Transcriptome Analysis of a Cefquinome-treated, Highly Resistant, and Virulent MRSA Strain Microbial Pathogenesis. Nov, 2021 | Pubmed ID: 34547409 Nanocapsules Modify Membrane Interaction of Polymyxin B to Enable Safe Systemic Therapy of Gram-negative Sepsis Science Advances. Aug, 2021 | Pubmed ID: 34362742 Investigating Auranofin for the Treatment of Infected Diabetic Pressure Ulcers in Mice and Dermal Toxicity in Pigs Scientific Reports. 05, 2021 | Pubmed ID: 34035383 High-throughput Screening Identifies a Novel Natural Product-inspired Scaffold Capable of Inhibiting Clostridioides Difficile in Vitro Scientific Reports. 05, 2021 | Pubmed ID: 34035338 In Vitro and in Vivo Activities of the Carbonic Anhydrase Inhibitor, Dorzolamide, Against Vancomycin-resistant Enterococci PeerJ. 2021 | Pubmed ID: 33850651 Sheep As a Potential Model of Intradiscal Infection by the Bacterium Veterinary Sciences. Mar, 2021 | Pubmed ID: 33809558 In Vivo Efficacy of Auranofin in a Hamster Model of Clostridioides Difficile Infection Scientific Reports. 03, 2021 | Pubmed ID: 33782498 Structure-Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity Against ACS Infectious Diseases. 07, 2021 | Pubmed ID: 33765392 -(1,3,4-Oxadiazol-2-yl)Benzamides As Antibacterial Agents Against International Journal of Molecular Sciences. Feb, 2021 | Pubmed ID: 33671065 Evaluation of Ebselen in Resolving a Methicillin-resistant Staphylococcus Aureus Infection of Pressure Ulcers in Obese and Diabetic Mice PloS One. 2021 | Pubmed ID: 33617589 Antibacterial Activity of Acetazolamide Antimicrobial Agents and Chemotherapy. 03, 2021 | Pubmed ID: 33495225 Aprepitant, an Antiemetic Agent, Interferes with Metal Ion Homeostasis of and Displays Potent Synergistic Interactions with Azole Drugs Virulence. 12, 2020 | Pubmed ID: 33100149 Discovery of Prenyltransferase Inhibitors with and Antibacterial Activity ACS Infectious Diseases. 11, 2020 | Pubmed ID: 33085463 Potent Synergistic Interactions Between Lopinavir and Azole Antifungal Drugs Against Emerging Multidrug-Resistant Candida Auris Antimicrobial Agents and Chemotherapy. 12, 2020 | Pubmed ID: 33046487 Repurposing the Veterinary Antiprotozoal Drug Ronidazole for the Treatment of Clostridioides Difficile Infection International Journal of Antimicrobial Agents. Dec, 2020 | Pubmed ID: 33045352 Ultrapotent Inhibitor of Growth, Which Suppresses Recurrence Journal of Medicinal Chemistry. 10, 2020 | Pubmed ID: 32960605 Development of Biphenylthiazoles Exhibiting Improved Pharmacokinetics and Potent Activity Against Intracellular ACS Infectious Diseases. 11, 2020 | Pubmed ID: 32897045 Peptide Nucleic Acids Inhibit Growth of Brucella Suis in Pure Culture and in Infected Murine Macrophages International Journal of Antimicrobial Agents. Apr, 2013 | Pubmed ID: 23305655 Effect of EntF Deletion on Iron Acquisition and Erythritol Metabolism by Brucella Abortus 2308 FEMS Microbiology Letters. Mar, 2011 | Pubmed ID: 21204922 Tightly Regulated Expression Vectors for Ochrobactrum Anthropi Current Microbiology. Apr, 2010 | Pubmed ID: 20237980 Brucellosis: a Re-emerging Zoonosis Veterinary Microbiology. Jan, 2010 | Pubmed ID: 19604656 Silica-antibiotic Hybrid Nanoparticles for Targeting Intracellular Pathogens Antimicrobial Agents and Chemotherapy. Oct, 2009 | Pubmed ID: 19667284 Plasmid-based System for High-level Gene Expression and Antisense Gene Knockdown in Bartonella Henselae Applied and Environmental Microbiology. Aug, 2009 | Pubmed ID: 19542333 Targeting Brucella Melitensis with Polymeric Nanoparticles Containing Streptomycin and Doxycycline FEMS Microbiology Letters. May, 2009 | Pubmed ID: 19493005 Brucella Abortus Strain RB51 Leucine Auxotroph As an Environmentally Safe Vaccine for Plasmid Maintenance and Antigen Overexpression Applied and Environmental Microbiology. Nov, 2008 | Pubmed ID: 18836016 Activity of Native Vs. Synthetic Promoters in Brucella FEMS Microbiology Letters. Nov, 2008 | Pubmed ID: 18811654 Reporter Genes for Real-time in Vive Monitoring of Ochrobactrum Anthropi Infection FEMS Microbiology Letters. Sep, 2008 | Pubmed ID: 18637041 Vectors for Enhanced Gene Expression and Protein Purification in Salmonella Gene. Sep, 2008 | Pubmed ID: 18621116 Construction of a High-efficiency Shuttle Vector for Histophilus Somni Journal of Microbiological Methods. Aug, 2008 | Pubmed ID: 18502523 Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium Meng Zhang1,2, Mohamed N. Seleem3, Ji-Xin Cheng1,2,4,5 1Department of Electrical and Computer Engineering, Boston University, 2Boston University Photonics Center, Boston University, 3Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, 4Department of Biomedical Engineering, Boston University, 5Department of Chemistry, Boston University JoVE 62398 Biology
Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium Meng Zhang1,2, Mohamed N. Seleem3, Ji-Xin Cheng1,2,4,5 1Department of Electrical and Computer Engineering, Boston University, 2Boston University Photonics Center, Boston University, 3Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, 4Department of Biomedical Engineering, Boston University, 5Department of Chemistry, Boston University JoVE 62398 Biology
