Naoaki Ishii Department of Health Management, School of Health Study Tokai University Biography Publications Institution JoVE Articles Naoaki Ishii has not added a biography. If you are Naoaki Ishii and would like to personalize this page please email our Author Liaison for assistance. Publications Long-term Administration of PDC Stimulative Lactic Acid Bacteria, Lactococcus Lactis Strain Plasma, Prevents Immune-senescence and Decelerates Individual Senescence Experimental Gerontology. Oct, 2018 | Pubmed ID: 29964182 Impaired P53/CEP-1 is Associated with Lifespan Extension Through an Age-related Imbalance in the Energy Metabolism of C. elegans Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Dec, 2017 | Pubmed ID: 29114996 Endogenous Reactive Oxygen Species Cause Astrocyte Defects and Neuronal Dysfunctions in the Hippocampus: a New Model for Aging Brain Aging Cell. Feb, 2017 | Pubmed ID: 27623715 Preparation of Clinically Useful Sennoside-reduced Rhubarb The Tokai Journal of Experimental and Clinical Medicine. Mar, 2016 | Pubmed ID: 27050892 Infertility and Recurrent Miscarriage with Complex II Deficiency-dependent Mitochondrial Oxidative Stress in Animal Models Mechanisms of Ageing and Development. Apr, 2016 | Pubmed ID: 26944226 A Combination of Mitochondrial Oxidative Stress and Excess Fat/Calorie Intake Accelerates Steatohepatitis by Enhancing Hepatic CC Chemokine Production in Mice PloS One. 2016 | Pubmed ID: 26745268 Association Between Insulin Resistance and Plasma Amino Acid Profile in Non-diabetic Japanese Subjects Journal of Diabetes Investigation. Jul, 2015 | Pubmed ID: 26221519 Ethyl Methanesulfonate Induces Mutations in Caenorhabditis Elegans Embryos at a High Frequency Mutation Research. Aug-Sep, 2014 | Pubmed ID: 25847271 Genetically Induced Oxidative Stress in Mice Causes Thrombocytosis, Splenomegaly and Placental Angiodysplasia That Leads to Recurrent Abortion Redox Biology. 2014 | Pubmed ID: 24936442 Haploinsufficiency of Akt1 Prolongs the Lifespan of Mice PloS One. 2013 | Pubmed ID: 23935948 Model Animals for the Study of Oxidative Stress from Complex II Biochimica Et Biophysica Acta. May, 2013 | Pubmed ID: 23142169 Oxidative Stress Induced Inflammation Initiates Functional Decline of Tear Production PloS One. 2012 | Pubmed ID: 23071526 Mitochondrial Superoxide Anion Overproduction in Tet-mev-1 Transgenic Mice Accelerates Age-dependent Corneal Cell Dysfunctions Investigative Ophthalmology & Visual Science. Aug, 2012 | Pubmed ID: 22786907 Mitochondrial Superoxide Anion (O(2)(-)) Inducible "mev-1" Animal Models for Aging Research BMB Reports. May, 2011 | Pubmed ID: 21615983 Interrelationships Between Mitochondrial Fusion, Energy Metabolism and Oxidative Stress During Development in Caenorhabditis Elegans Biochemical and Biophysical Research Communications. Jan, 2011 | Pubmed ID: 21144829 Mitochondrial Reactive Oxygen Species Generation by the SDHC V69E Mutation Causes Low Birth Weight and Neonatal Growth Retardation Mitochondrion. Jan, 2011 | Pubmed ID: 20870041 Post-dauer Life Span of Caenorhabditis Elegans Dauer Larvae Can Be Modified by X-irradiation Journal of Radiation Research. 2010 | Pubmed ID: 19851044 Beneficial Effects of Medical Advice Provided to Elderly Persons Under the Anti-aging Health Check-up System at Tokai University Tokyo Hospital The Tokai Journal of Experimental and Clinical Medicine. Dec, 2009 | Pubmed ID: 21319015 The Role of Mitochondrial Superoxide Anion (O2(-)) on Physiological Aging in C57BL/6J Mice Journal of Radiation Research. Jan, 2009 | Pubmed ID: 19218782 Cell Growth of the Mouse SDHC Mutant Cells Was Suppressed by Apoptosis Throughout Mitochondrial Pathway Bioscience Trends. Feb, 2008 | Pubmed ID: 20103895 Role of Oxidative Stress from Mitochondria on Aging and Cancer Cornea. Oct, 2007 | Pubmed ID: 17881913 Basic Principle of the Lifespan in the Nematode C. Elegans Mechanisms of Ageing and Development. Sep, 2007 | Pubmed ID: 17707465 The Role of the Electron Transport SDHC Gene on Lifespan and Cancer Mitochondrion. Feb-Apr, 2007 | Pubmed ID: 17321223 The Role of the Electron Transport Gene SDHC on Lifespan and Cancer Experimental Gerontology. Oct, 2006 | Pubmed ID: 16962276 Age-related Changes of Mitochondrial Structure and Function in Caenorhabditis Elegans Mechanisms of Ageing and Development. Oct, 2006 | Pubmed ID: 16893561 [Aging and Age-related Diseases Caused by Superoxide Anion Production from Mitochondria] Seikagaku. The Journal of Japanese Biochemical Society. Mar, 2006 | Pubmed ID: 16634564 [Why Do Peoples Age? the Mechanisms of Organismal Aging and Longevity] Nihon Shokakibyo Gakkai Zasshi = The Japanese Journal of Gastro-enterology. Feb, 2006 | Pubmed ID: 16506661 The Role of Stress in Ageing: Research on the Nematode, Caenorhabditis Elegans The British Journal of Dermatology. Dec, 2005 | Pubmed ID: 16280015 The P38 Signal Transduction Pathway Participates in the Oxidative Stress-mediated Translocation of DAF-16 to Caenorhabditis Elegans Nuclei Mechanisms of Ageing and Development. Jun-Jul, 2005 | Pubmed ID: 15888317 Effect of Oxidative Stress on Translocation of DAF-16 in Oxygen-sensitive Mutants, Mev-1 and Gas-1 of Caenorhabditis Elegans Mechanisms of Ageing and Development. Jun-Jul, 2005 | Pubmed ID: 15888316 Direct Measurement of Oxygen Consumption Rate on the Nematode Caenorhabditis Elegans by Using an Optical Technique Biochemical and Biophysical Research Communications. May, 2005 | Pubmed ID: 15809072 A Mutation in the SDHC Gene of Complex II Increases Oxidative Stress, Resulting in Apoptosis and Tumorigenesis Cancer Research. Jan, 2005 | Pubmed ID: 15665296 Coenzyme Q10 Can Prolong C. Elegans Lifespan by Lowering Oxidative Stress Mechanisms of Ageing and Development. Jan, 2004 | Pubmed ID: 14706236 A Complex II Defect Affects Mitochondrial Structure, Leading to Ced-3- and Ced-4-dependent Apoptosis and Aging The Journal of Biological Chemistry. Jun, 2003 | Pubmed ID: 12672828 VBP-1 is Necessary for Morphogenesis in Caenorhabditis Elegans Oncology Reports. Mar-Apr, 2003 | Pubmed ID: 12579260 Complex II Inactivation is Lethal in the Nematode Caenorhabditis Elegans Mitochondrion. Dec, 2002 | Pubmed ID: 16120320 Adaptive Responses to Oxidative Damage in Three Mutants of Caenorhabditis Elegans (age-1, Mev-1 and Daf-16) That Affect Life Span Mechanisms of Ageing and Development. Nov, 2002 | Pubmed ID: 12470895 Protein Oxidation During Aging of the Nematode Caenorhabditis Elegans Free Radical Biology & Medicine. Oct, 2002 | Pubmed ID: 12374613 [Mitochondrial Function and Aging] Nihon Rinsho. Japanese Journal of Clinical Medicine. Apr, 2002 | Pubmed ID: 12013849 Oxidative Stress and Aging in Caenorhabditis Elegans Free Radical Research. Dec, 2000 | Pubmed ID: 11237107 A Mutation in Succinate Dehydrogenase Cytochrome B Causes Oxidative Stress and Ageing in Nematodes Nature. Aug, 1998 | Pubmed ID: 9716135 Isolation and Genetic Analysis of Amber UvrA and UvrB Mutants Journal of Bacteriology. Apr, 1976 | Pubmed ID: 770438 Small-Scale Colorimetric Assays of Intracellular Lactate and Pyruvate in the Nematode Caenorhabditis elegans Sumino Yanase1,2, Kayo Yasuda3, Naoaki Ishii3 1Department of Health Science, School of Sports & Health Science, Daito Bunka University, 2Department of Molecular Life Science, School of Medicine, Tokai University, 3Department of Health Management, School of Health Study, Tokai University JoVE 57807 Biochemistry
Small-Scale Colorimetric Assays of Intracellular Lactate and Pyruvate in the Nematode Caenorhabditis elegans Sumino Yanase1,2, Kayo Yasuda3, Naoaki Ishii3 1Department of Health Science, School of Sports & Health Science, Daito Bunka University, 2Department of Molecular Life Science, School of Medicine, Tokai University, 3Department of Health Management, School of Health Study, Tokai University JoVE 57807 Biochemistry