Nichollas Scott Department of Microbiology and Immunology University of Melbourne Biography Publications Institution JoVE Articles Nichollas Scott Dr Scott is an Australian Research Council Future Fellow and group leader at the University of Melbourne. He received his PhD from the University of Sydney (2012) on MS characterisation of bacterial protein modifications and undertook postdoctoral training at the University of British Columbia (2012-2015) on proteomics-based systems biology. In 2016 Dr Scott returned to Australia and in 2017 he established his independent research group focusing on the characterisation of microbial glycosylation systems.Dr Scott’s work on glycoproteomics has demonstrated that microbial glycosylation events are both widespread and play a multifaceted role in microbes. These insights have resulted in recognition of his work across the fields of glycobiology, proteomics and microbiology in the form of awards including the International Glycoconjugate Organization Young Glycoscientist Award in 2019; the Australasian Proteomics Society 2017 Ken Mitchelhill Award as well as the Australian Society for Microbiology Frank Fenner Award in 2021. Publications Burkholderia PglL Enzymes Are Serine Preferring Oligosaccharyltransferases Which Target Conserved Proteins Across the Burkholderia Genus Communications Biology. 09, 2021 | Pubmed ID: 34493791 An Atlas of Protein-protein Interactions Across Mouse Tissues Cell. Jul, 2021 | Pubmed ID: 34214469 Editorial Overview: Systems Biology and the Rise and Rise of Omics Approaches Current Opinion in Chemical Biology. 02, 2021 | Pubmed ID: 33676636 TLR2-mediated Activation of Innate Responses in the Upper Airways Confers Antiviral Protection of the Lungs JCI Insight. 03, 2021 | Pubmed ID: 33561017 Editorial Overview: Systems Biology and the Rise and Rise of Omics Approaches Current Opinion in Chemical Biology. Jan, 2021 | Pubmed ID: 33419639 Glycoproteomics: Growing Up Fast Current Opinion in Structural Biology. 06, 2021 | Pubmed ID: 33278752 Proteomic Identification of Coxiella Burnetii Effector Proteins Targeted to the Host Cell Mitochondria During Infection Molecular & Cellular Proteomics : MCP. Dec, 2020 | Pubmed ID: 33177156 The Effector SseK3 Targets Small Rab GTPases Frontiers in Cellular and Infection Microbiology. Month, 2020 | Pubmed ID: 32974215 Influence of Protein Glycosylation on Physiology Frontiers in Microbiology. Month, 2020 | Pubmed ID: 32625174 Open Database Searching Enables the Identification and Comparison of Bacterial Glycoproteomes Without Defining Glycan Compositions Prior to Searching Molecular & Cellular Proteomics : MCP. 09, 2020 | Pubmed ID: 32576591 Biogenesis of the Spacious -Containing Vacuole Depends on Host Transcription Factors TFEB and TFE3 Infection and Immunity. Feb, 2020 | Pubmed ID: 31818957 Loss of -Linked Protein Glycosylation in Burkholderia Cenocepacia Impairs Biofilm Formation and Siderophore Activity and Alters Transcriptional Regulators MSphere. 11, 2019 | Pubmed ID: 31722994 Low PH Exposure During Immunoglobulin G Purification Methods Results in Aggregates That Avidly Bind Fcγ Receptors: Implications for Measuring Fc Dependent Antibody Functions Frontiers in Immunology. Month, 2019 | Pubmed ID: 31681303 Expanding Our Understanding of the Role of Microbial Glycoproteomes Through High-throughput Mass Spectrometry Approaches Glycoconjugate Journal. 08, 2019 | Pubmed ID: 31270739 Protein -fucosyltransferase 2-mediated -glycosylation of the Adhesin MIC2 is Dispensable for Tachyzoite Infection The Journal of Biological Chemistry. 02, 2019 | Pubmed ID: 30514763 Surface Exposure and Packing of Lipoproteins into Outer Membrane Vesicles Are Coupled Processes in MSphere. 11, 2018 | Pubmed ID: 30404931 The Bacterial Arginine Glycosyltransferase Effector NleB Preferentially Modifies Fas-associated Death Domain Protein (FADD) The Journal of Biological Chemistry. 10, 2017 | Pubmed ID: 28860194 Characterizing Glycoproteins by Mass Spectrometry in Campylobacter Jejuni Methods in Molecular Biology (Clifton, N.J.). Month, 2017 | Pubmed ID: 27885610 The Application of Open Searching-based Approaches for the Identification of Acinetobacter baumannii O-linked Glycopeptides Jessica M. Lewis*1, Pauline M. L. Coulon*1, Taylor A. McDaniels*1, Nichollas E. Scott1 1Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne JoVE 63242 Biochemistry
The Application of Open Searching-based Approaches for the Identification of Acinetobacter baumannii O-linked Glycopeptides Jessica M. Lewis*1, Pauline M. L. Coulon*1, Taylor A. McDaniels*1, Nichollas E. Scott1 1Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne JoVE 63242 Biochemistry
