Owen J.T. McCarty

Publications

• Measurement Science in the Circulatory System
  Cellular and Molecular Bioengineering. Mar, 2014  |   Pubmed ID: 24563678
• Network Signatures of Nuclear and Cytoplasmic Density Alterations in a Model of Pre and Postmetastatic Colorectal Cancer
  Journal of Biomedical Optics. Jan, 2014  |   Pubmed ID: 24441943
• Factor XII Inhibition Reduces Thrombus Formation in a Primate Thrombosis Model
  Blood. Mar, 2014  |   Pubmed ID: 24408325
• Physical Biology in Cancer. 2. The Physical Biology of Circulating Tumor Cells
  American Journal of Physiology. Cell Physiology. Jan, 2014  |   Pubmed ID: 24133063
• A Theme Series on Physical Biology in Cancer in AJP-Cell
  American Journal of Physiology. Cell Physiology. Jan, 2014  |   Pubmed ID: 24067917
• Rac and Cdc42 Team Up for Platelets
  Blood. Oct, 2013  |   Pubmed ID: 24178962
• Phosphatidylserine Index As a Marker of the Procoagulant Phenotype of Acute Myelogenous Leukemia Cells
  Physical Biology. Oct, 2013  |   Pubmed ID: 24104188
• Histone Deacetylase 6-mediated Deacetylation of α-tubulin Coordinates Cytoskeletal and Signaling Events During Platelet Activation
  American Journal of Physiology. Cell Physiology. Dec, 2013  |   Pubmed ID: 24025866
• P21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils
  PloS One. 2013  |   Pubmed ID: 24019894
• Role of Coagulation in the Recruitment of Colon Adenocarcinoma Cells to Thrombus Under Shear
  American Journal of Physiology. Cell Physiology. Nov, 2013  |   Pubmed ID: 23903698
• The PAK System Links Rho GTPase Signaling to Thrombin-mediated Platelet Activation
  American Journal of Physiology. Cell Physiology. Sep, 2013  |   Pubmed ID: 23784547
• Pivotal Role for the MTOR Pathway in the Formation of Neutrophil Extracellular Traps Via Regulation of Autophagy
  American Journal of Physiology. Cell Physiology. Aug, 2013  |   Pubmed ID: 23720022
• Microfluidics and Coagulation Biology
  Annual Review of Biomedical Engineering. 2013  |   Pubmed ID: 23642241
• P21 Activated Kinase Signaling Coordinates Glycoprotein Receptor VI-mediated Platelet Aggregation, Lamellipodia Formation, and Aggregate Stability Under Shear
  Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2013  |   Pubmed ID: 23640496
• A Physical Sciences Network Characterization of Non-tumorigenic and Metastatic Cells
  Scientific Reports. 2013  |   Pubmed ID: 23618955
• Physiological Levels of Blood Coagulation Factors IX and X Control Coagulation Kinetics in an in Vitro Model of Circulating Tissue Factor
  Physical Biology. Jun, 2013  |   Pubmed ID: 23585459
• Quantification of Volume, Mass, and Density of Thrombus Formation Using Brightfield and Differential Interference Contrast Microscopy
  Journal of Biomedical Optics. Jan, 2013  |   Pubmed ID: 23348747
• Hyaluronan Oligosaccharides Perturb Lymphocyte Slow Rolling on Brain Vascular Endothelial Cells: Implications for Inflammatory Demyelinating Disease
  Matrix Biology : Journal of the International Society for Matrix Biology. Apr, 2013  |   Pubmed ID: 23333375
• Gammaherpesvirus Latency Induces Antibody-associated Thrombocytopenia in Mice
  Journal of Autoimmunity. May, 2013  |   Pubmed ID: 23245703
• Molecular Imaging of Inflammation and Platelet Adhesion in Advanced Atherosclerosis Effects of Antioxidant Therapy with NADPH Oxidase Inhibition
  Circulation. Cardiovascular Imaging. Jan, 2013  |   Pubmed ID: 23239832
• Exogenous Modification of Platelet Membranes with the Omega-3 Fatty Acids EPA and DHA Reduces Platelet Procoagulant Activity and Thrombus Formation
  American Journal of Physiology. Cell Physiology. Feb, 2013  |   Pubmed ID: 23174566
• Inhibition of Factor XII-Mediated Activation of Factor XI Provides Protection Against Experimental Acute Ischemic Stroke in Mice
  Translational Stroke Research. Sep, 2012  |   Pubmed ID: 23634198
• Development of a Label-free Imaging Technique for the Quantification of Thrombus Formation
  Cellular and Molecular Bioengineering. Dec, 2012  |   Pubmed ID: 23585817
• Modeling and Simulation of Procoagulant Circulating Tumor Cells in Flow
  Frontiers in Oncology. 2012  |   Pubmed ID: 23050240
• Measurement of Single Cell Refractive Index, Dry Mass, Volume, and Density Using a Transillumination Microscope
  Physical Review Letters. Sep, 2012  |   Pubmed ID: 23005682
• Do Circulating Tumor Cells Play a Role in Coagulation and Thrombosis?
  Frontiers in Oncology. 2012  |   Pubmed ID: 22973557
• Development of Coagulation Factor Probes for the Identification of Procoagulant Circulating Tumor Cells
  Frontiers in Oncology. 2012  |   Pubmed ID: 22973554
• Quantification of Cellular Volume and Sub-cellular Density Fluctuations: Comparison of Normal Peripheral Blood Cells and Circulating Tumor Cells Identified in a Breast Cancer Patient
  Frontiers in Oncology. 2012  |   Pubmed ID: 22934287
• Hyaluronan Anchored to Activated CD44 on Central Nervous System Vascular Endothelial Cells Promotes Lymphocyte Extravasation in Experimental Autoimmune Encephalomyelitis
  The Journal of Biological Chemistry. Sep, 2012  |   Pubmed ID: 22865853
• Optical Quantification of Cellular Mass, Volume, and Density of Circulating Tumor Cells Identified in an Ovarian Cancer Patient
  Frontiers in Oncology. 2012  |   Pubmed ID: 22826822
• Regulation of the MTOR-Rac1 Axis in Platelet Function
  Small GTPases. Jan-Mar, 2012  |   Pubmed ID: 22714420
• Inhibition of Factor XI Activation Attenuates Inflammation and Coagulopathy While Improving the Survival of Mouse Polymicrobial Sepsis
  Blood. May, 2012  |   Pubmed ID: 22442348
• Optical Detection of Indocyanine Green Encapsulated Biocompatible Poly (lactic-co-glycolic) Acid Nanoparticles with Photothermal Optical Coherence Tomography
  Optics Letters. Mar, 2012  |   Pubmed ID: 22378459
• Platelet Shape Change and Spreading
  Methods in Molecular Biology (Clifton, N.J.). 2012  |   Pubmed ID: 22130702
• Activated Factor XI Inhibits Chemotaxis of Polymorphonuclear Leukocytes
  Journal of Leukocyte Biology. Nov, 2011  |   Pubmed ID: 21807745
• S6K1 and MTOR Regulate Rac1-driven Platelet Activation and Aggregation
  Blood. Sep, 2011  |   Pubmed ID: 21757621
• Thrombin Mutant W215A/E217A Treatment Improves Neurological Outcome and Reduces Cerebral Infarct Size in a Mouse Model of Ischemic Stroke
  Stroke; a Journal of Cerebral Circulation. Jun, 2011  |   Pubmed ID: 21512172
• Breakup Feared After Filamin Leaves GPIb
  Blood. Mar, 2011  |   Pubmed ID: 21372161
• Molecular Imaging of Activated Von Willebrand Factor to Detect High-risk Atherosclerotic Phenotype
  JACC. Cardiovascular Imaging. Sep, 2010  |   Pubmed ID: 20846630
• A Role for Factor XIIa-mediated Factor XI Activation in Thrombus Formation in Vivo
  Blood. Nov, 2010  |   Pubmed ID: 20634381
• Safety and Antithrombotic Efficacy of Moderate Platelet Count Reduction by Thrombopoietin Inhibition in Primates
  Science Translational Medicine. Jun, 2010  |   Pubmed ID: 20574069
• Binding of Recombinant T Cell Receptor Ligands (RTL) to Antigen Presenting Cells Prevents Upregulation of CD11b and Inhibits T Cell Activation and Transfer of Experimental Autoimmune Encephalomyelitis
  Journal of Neuroimmunology. Aug, 2010  |   Pubmed ID: 20546940
• Spatial Distribution of Factor Xa, Thrombin, and Fibrin(ogen) on Thrombi at Venous Shear
  PloS One. 2010  |   Pubmed ID: 20454680
• Cytoskeletal Structure Regulates Endothelial Cell Immunogenicity Independent of Fluid Shear Stress
  American Journal of Physiology. Cell Physiology. Feb, 2010  |   Pubmed ID: 19923423
• Effect of Sex Difference on Platelet Adhesion, Spreading and Aggregate Formation Under Flow
  Thrombosis and Haemostasis. Nov, 2009  |   Pubmed ID: 19888535
• Identification of Coagulation Factor XI As a Ligand for Platelet Apolipoprotein E Receptor 2 (ApoER2)
  Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2009  |   Pubmed ID: 19661487
• Single Particle Quantum Dot Imaging Achieves Ultrasensitive Detection Capabilities for Western Immunoblot Analysis
  ACS Nano. Jun, 2009  |   Pubmed ID: 19453141
• Small-molecule Inhibitors of Integrin Alpha2beta1 That Prevent Pathological Thrombus Formation Via an Allosteric Mechanism
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2009  |   Pubmed ID: 19141632
• Activated Protein C Ligation of ApoER2 (LRP8) Causes Dab1-dependent Signaling in U937 Cells
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2009  |   Pubmed ID: 19116273
• Distinct Extracellular Matrix Microenvironments of Progenitor and Carotid Endothelial Cells
  Journal of Biomedical Materials Research. Part A. Nov, 2009  |   Pubmed ID: 18985765
• Prevention of Vascular Graft Occlusion and Thrombus-associated Thrombin Generation by Inhibition of Factor XI
  Blood. Jan, 2009  |   Pubmed ID: 18945968
• Capture of Flowing Endothelial Cells Using Surface-immobilized Anti-kinase Insert Domain Receptor Antibody
  Tissue Engineering. Part C, Methods. Jun, 2008  |   Pubmed ID: 18544026
• Thrombin Mutant W215A/E217A Acts As a Platelet GPIb Antagonist
  Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2008  |   Pubmed ID: 17962622
• The Leech Product Saratin is a Potent Inhibitor of Platelet Integrin Alpha2beta1 and Von Willebrand Factor Binding to Collagen
  The FEBS Journal. Mar, 2007  |   Pubmed ID: 17489103
• Minimal Regulation of Platelet Activity by PECAM-1
  Platelets. Feb, 2007  |   Pubmed ID: 17365855
• Relative Antithrombotic and Antihemostatic Effects of Protein C Activator Versus Low-molecular-weight Heparin in Primates
  Blood. May, 2007  |   Pubmed ID: 17227834
• GPVI Potentiation of Platelet Activation by Thrombin and Adhesion Molecules Independent of Src Kinases and Syk
  Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2007  |   Pubmed ID: 17110603
• Vav Family Proteins Are Required for Optimal Regulation of PLCgamma2 by Integrin AlphaIIbbeta3
  The Biochemical Journal. Feb, 2007  |   Pubmed ID: 17054426
• Distinct but Critical Roles for Integrin AlphaIIbbeta3 in Platelet Lamellipodia Formation on Fibrinogen, Collagen-related Peptide and Thrombin
  The FEBS Journal. Nov, 2006  |   Pubmed ID: 17032352
• Laminin Stimulates Spreading of Platelets Through Integrin Alpha6beta1-dependent Activation of GPVI
  Blood. Feb, 2006  |   Pubmed ID: 16219796
• Rac1 is Essential for Platelet Lamellipodia Formation and Aggregate Stability Under Flow
  The Journal of Biological Chemistry. Nov, 2005  |   Pubmed ID: 16195235
• Preferential Binding of Platelets to Monocytes over Neutrophils Under Flow
  Biochemical and Biophysical Research Communications. Apr, 2005  |   Pubmed ID: 15721313
• Evaluation of Platelet Antagonists in in Vitro Flow Models of Thrombosis
  Methods in Molecular Medicine. 2004  |   Pubmed ID: 14733325
• Exogenous Eosinophil Activation Converts PSGL-1-dependent Binding to CD18-dependent Stable Adhesion to Platelets in Shear Flow
  American Journal of Physiology. Cell Physiology. May, 2003  |   Pubmed ID: 12529243
• Fluid Shear Regulates the Kinetics and Molecular Mechanisms of Activation-dependent Platelet Binding to Colon Carcinoma Cells
  Biophysical Journal. Aug, 2002  |   Pubmed ID: 12124268
• Comparative Efficacy Between the Glycoprotein IIb/IIIa Antagonists Roxifiban and Orbofiban in Inhibiting Platelet Responses in Flow Models of Thrombosis
  Journal of Cardiovascular Pharmacology. Apr, 2002  |   Pubmed ID: 11904529