Rama Ranganathan Green Center for Systems Biology University of Texas Southwestern Medical Center Biography Publications Institution JoVE Articles Rama Ranganathan has not added a biography. If you are Rama Ranganathan and would like to personalize this page please email our Author Liaison for assistance. Publications The Context-Dependence of Mutations: A Linkage of Formalisms PLoS Computational Biology. Jun, 2016 | Pubmed ID: 27337695 Origins of Allostery and Evolvability in Proteins: A Case Study Cell. Jun, 2016 | Pubmed ID: 27321669 Evolution-Based Functional Decomposition of Proteins PLoS Computational Biology. Jun, 2016 | Pubmed ID: 27254668 Paediatric Retinoblastoma in India: Evidence from the National Cancer Registry Programme Asian Pacific Journal of Cancer Prevention : APJCP. 2015 | Pubmed ID: 26028071 Evolvability As a Function of Purifying Selection in TEM-1 β-lactamase Cell. Feb, 2015 | Pubmed ID: 25723163 A Novel Allosteric Mechanism in the Cysteine Peptidase Cathepsin K Discovered by Computational Methods Nature Communications. 2014 | Pubmed ID: 24518821 Systems-level Characterization of the Kernel Mechanism of the Cyanobacterial Circadian Oscillator Bio Systems. Mar, 2014 | Pubmed ID: 24444761 Evolution-based Design of Proteins Methods in Enzymology. 2013 | Pubmed ID: 23422432 The Spatial Architecture of Protein Function and Adaptation Nature. Nov, 2012 | Pubmed ID: 23041932 Quantifying the Rhythm of KaiB-C Interaction for in Vitro Cyanobacterial Circadian Clock PloS One. 2012 | Pubmed ID: 22900029 XPD Lys751Gln Increases the Risk of Breast Cancer Oncology Letters. Jan, 2011 | Pubmed ID: 22870145 Hot Spots for Allosteric Regulation on Protein Surfaces Cell. Dec, 2011 | Pubmed ID: 22196731 Prognostic Factors in Patients with Node-negative Gastric Cancer: an Indian Experience World Journal of Surgical Oncology. 2011 | Pubmed ID: 21554745 An Interdomain Sector Mediating Allostery in Hsp70 Molecular Chaperones Molecular Systems Biology. Sep, 2010 | Pubmed ID: 20865007 Cure Models for Estimating Hospital-based Breast Cancer Survival Asian Pacific Journal of Cancer Prevention : APJCP. 2010 | Pubmed ID: 20843121 Autophagy: Snapshot of the Network Nature. Jul, 2010 | Pubmed ID: 20596005 Protein Sectors: Evolutionary Units of Three-dimensional Structure Cell. Aug, 2009 | Pubmed ID: 19703402 CYP17 (T34C), CYP19 (Trp39Arg), and FGFR2 (C906T) Polymorphisms and the Risk of Breast Cancer in South Indian Women Asian Pacific Journal of Cancer Prevention : APJCP. Jan-Mar, 2009 | Pubmed ID: 19469636 Surface Sites for Engineering Allosteric Control in Proteins Science (New York, N.Y.). Oct, 2008 | Pubmed ID: 18927392 Lack of Active Follow-up of Cancer Patients in Chennai, India: Implications for Population-based Survival Estimates Bulletin of the World Health Organization. Jul, 2008 | Pubmed ID: 18670662 Systems Analysis of the Single Photon Response in Invertebrate Photoreceptors Proceedings of the National Academy of Sciences of the United States of America. Jul, 2008 | Pubmed ID: 18653755 Childhood Cancers in Chennai, India, 1990-2001: Incidence and Survival International Journal of Cancer. Jun, 2008 | Pubmed ID: 18324630 TGFbeta1 (Leu10Pro), P53 (Arg72Pro) Can Predict for Increased Risk for Breast Cancer in South Indian Women and TGFbeta1 Pro (Leu10Pro) Allele Predicts Response to Neo-adjuvant Chemo-radiotherapy Breast Cancer Research and Treatment. Nov, 2008 | Pubmed ID: 18058229 Retrospective Analysis of Locally Advanced Noninflammatory Breast Cancer from Chennai, South India, 1990-1999 International Journal of Radiation Oncology, Biology, Physics. Jan, 2008 | Pubmed ID: 17869447 Biochemistry. Signaling Across the Cell Membrane Science (New York, N.Y.). Nov, 2007 | Pubmed ID: 18033872 Dynamic Scaffolding in a G Protein-coupled Signaling System Cell. Oct, 2007 | Pubmed ID: 17923089 Role of GSTM1 (Null/Present), GSTP1 (Ile105Val) and P53 (Arg72Pro) Genetic Polymorphisms and the Risk of Breast Cancer: a Case Control Study from South India Asian Pacific Journal of Cancer Prevention : APJCP. Apr-Jun, 2007 | Pubmed ID: 17696741 Elevated Basal Slippage Mutation Rates Among the Canidae The Journal of Heredity. 2007 | Pubmed ID: 17437958 Signal Transduction Pathway of TonB-dependent Transporters Proceedings of the National Academy of Sciences of the United States of America. Jan, 2007 | Pubmed ID: 17197416 Knowledge-based Potentials in Protein Design Current Opinion in Structural Biology. Aug, 2006 | Pubmed ID: 16843652 A Global Analysis of Cross-talk in a Mammalian Cellular Signalling Network Nature Cell Biology. Jun, 2006 | Pubmed ID: 16699502 Natural-like Function in Artificial WW Domains Nature. Sep, 2005 | Pubmed ID: 16177795 Evolutionary Information for Specifying a Protein Fold Nature. Sep, 2005 | Pubmed ID: 16177782 Structural Determinants of Allosteric Ligand Activation in RXR Heterodimers Cell. Feb, 2004 | Pubmed ID: 15016376 Local Complexity of Amino Acid Interactions in a Protein Core Proceedings of the National Academy of Sciences of the United States of America. Jan, 2004 | Pubmed ID: 14684834 Allosteric Determinants in Guanine Nucleotide-binding Proteins Proceedings of the National Academy of Sciences of the United States of America. Nov, 2003 | Pubmed ID: 14623969 Cell Biology. A Matter of Life or Death Science (New York, N.Y.). Mar, 2003 | Pubmed ID: 12637727 Evolutionarily Conserved Networks of Residues Mediate Allosteric Communication in Proteins Nature Structural Biology. Jan, 2003 | Pubmed ID: 12483203 Overview of the Alliance for Cellular Signaling Nature. Dec, 2002 | Pubmed ID: 12478301 Knowledge-based Potential Functions in Protein Design Current Opinion in Structural Biology. Aug, 2002 | Pubmed ID: 12163066 A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing Michael Allen Stiffler1, Subu K Subramanian1, Victor H Salinas1, Rama Ranganathan1 1Green Center for Systems Biology, University of Texas Southwestern Medical Center JoVE 54119 Biology
A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing Michael Allen Stiffler1, Subu K Subramanian1, Victor H Salinas1, Rama Ranganathan1 1Green Center for Systems Biology, University of Texas Southwestern Medical Center JoVE 54119 Biology