Richard L. Leask Chemical Engineering McGill University Biography Publications Institution JoVE Articles Richard L. Leask has not added a biography. If you are Richard L. Leask and would like to personalize this page please email our Author Liaison for assistance. Publications Statin Therapy Influences Endothelial Cell Morphology and F-actin Cytoskeleton Structure when Exposed to Static and Laminar Shear Stress Conditions Life Sciences. May, 2013 | Pubmed ID: 23517776 Designing Green Plasticizers: Influence of Alkyl Chain Length on Biodegradation and Plasticization Properties of Succinate Based Plasticizers Chemosphere. Apr, 2013 | Pubmed ID: 23340052 Use of Inert Gas Jets to Measure the Forces Required for Mechanical Gene Transfection Biomedical Engineering Online. 2012 | Pubmed ID: 22963645 Regional Variations in Canine Descending Aortic Tissue Mechanical Properties Change with Formalin Fixation Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Sep-Oct, 2012 | Pubmed ID: 22300500 Effects of Di-(2-ethylhexyl) Phthalate and Four of Its Metabolites on Steroidogenesis in MA-10 Cells Ecotoxicology and Environmental Safety. May, 2012 | Pubmed ID: 22236953 Differential Response of Endothelial Cells to Simvastatin when Conditioned with Steady, Non-reversing Pulsatile or Oscillating Shear Stress Annals of Biomedical Engineering. Jan, 2011 | Pubmed ID: 20737288 Laminar Shear Stress Prevents Simvastatin-induced Adhesion Molecule Expression in Cytokine Activated Endothelial Cells European Journal of Pharmacology. Dec, 2010 | Pubmed ID: 20863785 Endothelial Cell Morphologic Response to Asymmetric Stenosis Hemodynamics: Effects of Spatial Wall Shear Stress Gradients Journal of Biomechanical Engineering. Aug, 2010 | Pubmed ID: 20670062 The Response of Human Aortic Endothelial Cells in a Stenotic Hemodynamic Environment: Effect of Duration, Magnitude, and Spatial Gradients in Wall Shear Stress Journal of Biomechanical Engineering. Jul, 2010 | Pubmed ID: 20590293 Effect of Simvastatin on Kruppel-like Factor2, Endothelial Nitric Oxide Synthase and Thrombomodulin Expression in Endothelial Cells Under Shear Stress Life Sciences. Jul, 2010 | Pubmed ID: 20493886 Regional Dependency of the Vascular Smooth Muscle Cell Contribution to the Mechanical Properties of the Pig Ascending Aortic Tissue Journal of Biomechanics. Aug, 2010 | Pubmed ID: 20478560 Neutrophil Adhesion on Endothelial Cells in a Novel Asymmetric Stenosis Model: Effect of Wall Shear Stress Gradients Annals of Biomedical Engineering. Sep, 2010 | Pubmed ID: 20387119 Concentration and Time Effects of Dextran Exposure on Endothelial Cell Viability, Attachment, and Inflammatory Marker Expression in Vitro Annals of Biomedical Engineering. Apr, 2010 | Pubmed ID: 20108164 Second Harmonic Generation Microscopy to Investigate Collagen Configuration: a Pericarditis Case Study Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Jul-Aug, 2010 | Pubmed ID: 19632137 The Development of 3-D, in Vitro, Endothelial Culture Models for the Study of Coronary Artery Disease Biomedical Engineering Online. 2009 | Pubmed ID: 19863806 A Comparison of Mechanical Properties of Materials Used in Aortic Arch Reconstruction The Annals of Thoracic Surgery. Nov, 2009 | Pubmed ID: 19853098 Local Mechanical and Structural Properties of Healthy and Diseased Human Ascending Aorta Tissue Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Mar-Apr, 2009 | Pubmed ID: 18402840 Impact of Degradation Products of Sulfamethoxazole on Mammalian Cultured Cells Environmental Toxicology. Aug, 2008 | Pubmed ID: 18247415 Time-dependent 3D Simulations of the Hemodynamics in a Stented Coronary Artery Biomedical Materials (Bristol, England). Mar, 2007 | Pubmed ID: 18458417 Mechanical Properties and Microscopic Findings of a Dacron Graft Explanted 27 Years After Coarctation Repair The Journal of Thoracic and Cardiovascular Surgery. Dec, 2007 | Pubmed ID: 18023686 Effects of Diffusion Coefficients and Struts Apposition Using Numerical Simulations for Drug Eluting Coronary Stents Journal of Biomechanical Engineering. Oct, 2007 | Pubmed ID: 17887899 Pathologic Analysis of 19 Heart Valves with Silver-coated Sewing Rings Journal of Cardiac Surgery. Nov-Dec, 2006 | Pubmed ID: 17073948 Morphological Findings in 192 Surgically Excised Native Mitral Valves The Canadian Journal of Cardiology. Oct, 2006 | Pubmed ID: 17036100 Normal Wound Healing in Mice Deficient for Fibulin-5, an Elastin Binding Protein Essential for Dermal Elastic Fiber Assembly The Journal of Investigative Dermatology. Dec, 2006 | Pubmed ID: 16902421 Invited Commentary The Annals of Thoracic Surgery. Mar, 2006 | Pubmed ID: 16488696 Morphological Findings in Explanted Toronto Stentless Porcine Valves Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Jan-Feb, 2006 | Pubmed ID: 16414456 Image Based Biomechanics of Coronary Plaque Studies in Health Technology and Informatics. 2005 | Pubmed ID: 15923740 Human Saphenous Vein Coronary Artery Bypass Graft Morphology, Geometry and Hemodynamics Annals of Biomedical Engineering. Mar, 2005 | Pubmed ID: 15868720 Artificial Chordae Tendinae: Long-term Changes Journal of Cardiac Surgery. Jan-Feb, 2005 | Pubmed ID: 15673420 Intimal Thickness is Not Associated with Wall Shear Stress Patterns in the Human Right Coronary Artery Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2004 | Pubmed ID: 15472129 Hemodynamic Effects of Clot Entrapment in the TrapEase Inferior Vena Cava Filter Journal of Vascular and Interventional Radiology : JVIR. May, 2004 | Pubmed ID: 15126659 The Relationship Between Wall Shear Stress Distributions and Intimal Thickening in the Human Abdominal Aorta Biomedical Engineering Online. Nov, 2003 | Pubmed ID: 14641919 Mechanical Heart Valve Prostheses: Identification and Evaluation (erratum) Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Nov-Dec, 2003 | Pubmed ID: 14630298 Primary Cardiac Sarcoma Involving the Pulmonary Artery and Valve The Canadian Journal of Cardiology. Jun, 2003 | Pubmed ID: 12813618 Biological Replacement Heart Valves. Identification and Evaluation Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. May-Jun, 2003 | Pubmed ID: 12763552 Host Tissue Overgrowth in a Mitral Valve Conserving Procedure Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Mar-Apr, 2003 | Pubmed ID: 12684164 Stentless Porcine Valves: New Mode of Failure The Canadian Journal of Cardiology. Feb, 2003 | Pubmed ID: 12601444 Mechanical Heart Valve Prostheses: Identification and Evaluation Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Jan-Feb, 2003 | Pubmed ID: 12598013 Endothelium and Valvular Diseases of the Heart Microscopy Research and Technique. Feb, 2003 | Pubmed ID: 12539167 Genetic Abnormalities of the Endothelium Microscopy Research and Technique. Jan, 2003 | Pubmed ID: 12500258 Pulmonary Site Porcine Bioprosthesis: Evaluation at 14 Years The Canadian Journal of Cardiology. Nov, 2002 | Pubmed ID: 12464980 Images in Cardiovascular Medicine. Pulmonary Site Bioprosthesis: Failure at 15 Years Circulation. Aug, 2002 | Pubmed ID: 12196349 Clinical and Pathophysiological Implications of a Bicuspid Aortic Valve Circulation. Aug, 2002 | Pubmed ID: 12186790 Chronic Aortic Dissection: 27 Years After Aortic Valve Replacement The Canadian Journal of Cardiology. Apr, 2002 | Pubmed ID: 11992139 不活性ガスジェットを用いて接着した細胞の透過性 Scott Cooper1, Paul Jonak1, Guillaume Chouinard-Pelletier1, Sylvain Coulombe1, Elizabeth Jones1, Richard L. Leask1,2 1Chemical Engineering, McGill University, 2Montreal Heart Institute JoVE 50612 Bioengineering
不活性ガスジェットを用いて接着した細胞の透過性 Scott Cooper1, Paul Jonak1, Guillaume Chouinard-Pelletier1, Sylvain Coulombe1, Elizabeth Jones1, Richard L. Leask1,2 1Chemical Engineering, McGill University, 2Montreal Heart Institute JoVE 50612 Bioengineering