Richard Cubbon

Publications

• Inflammation, Infection, and Cardiovascular Risk
  Lancet (London, England). Mar, 2024  |   Pubmed ID: 38492937
• Molecular Mechanisms of Diabetic Heart Disease: Insights from Transcriptomic Technologies
  Diabetes & Vascular Disease Research. 2023  |   Pubmed ID: 38116627
• Association Between Type 2 Diabetes and Changes in Myocardial Structure, Contractile Function, Energetics, and Blood Flow Before and After Aortic Valve Replacement in Patients With Severe Aortic Stenosis
  Circulation. Oct, 2023  |   Pubmed ID: 37746744
• Relationship Among Diabetes, Obesity, and Cardiovascular Disease Phenotypes: A UK Biobank Cohort Study
  Diabetes Care. Aug, 2023  |   Pubmed ID: 37368983
• Independent Endothelial Functions of PIEZO1 and TRPV4 in Hepatic Portal Vein and Predominance of PIEZO1 in Mechanical and Osmotic Stress
  Liver International : Official Journal of the International Association for the Study of the Liver. Sep, 2023  |   Pubmed ID: 37349903
• PIEZO1 and PECAM1 Interact at Cell-cell Junctions and Partner in Endothelial Force Sensing
  Communications Biology. Apr, 2023  |   Pubmed ID: 37005489
• Guideline-directed Medical Therapy is Similarly Effective in Heart Failure with Mildly Reduced Ejection Fraction
  Clinical Research in Cardiology : Official Journal of the German Cardiac Society. Jan, 2023  |   Pubmed ID: 35781605
• Correction: Advanced Care Planning During the COVID-19 Pandemic: Ceiling of Care Decisions and Their Implications for Observational Data
  BMC Palliative Care. Dec, 2022  |   Pubmed ID: 36527047
• Maternal Cardiac Changes in Women With Obesity and Gestational Diabetes Mellitus
  Diabetes Care. Dec, 2022  |   Pubmed ID: 36099225
• Reduction of Heart Failure Guideline-directed Medication During Hospitalization: Prevalence, Risk Factors, and Outcomes
  ESC Heart Failure. Oct, 2022  |   Pubmed ID: 35796239
• Atrial Fibrillation and Risk of Progressive Heart Failure in Patients with Preserved Ejection Fraction Heart Failure
  ESC Heart Failure. Oct, 2022  |   Pubmed ID: 35790085
• Coexistent Diabetes Is Associated With the Presence of Adverse Phenotypic Features in Patients With Hypertrophic Cardiomyopathy
  Diabetes Care. Aug, 2022  |   Pubmed ID: 35789379
• Cixutumumab Reveals a Critical Role for IGF-1 in Adipose and Hepatic Tissue Remodelling During the Development of Diet-induced Obesity
  Adipocyte. Dec, 2022  |   Pubmed ID: 35734881
• Systemic Inflammation Is Associated With Future Risk of Fatal Infection: An Observational Cohort Study
  The Journal of Infectious Diseases. Aug, 2022  |   Pubmed ID: 35535512
• Coronary Microvascular Function and Visceral Adiposity in Patients with Normal Body Weight and Type 2 Diabetes
  Obesity (Silver Spring, Md.). May, 2022  |   Pubmed ID: 35357083
• Diabetes Mellitus and the Causes of Hospitalisation in People with Heart Failure
  Diabetes & Vascular Disease Research. 2022  |   Pubmed ID: 35236158
• Prospective Longitudinal Characterization of the Relationship Between Diabetes and Cardiac Structural and Functional Changes
  Cardiology Research and Practice. 2022  |   Pubmed ID: 35178251
• Endothelial Cell Fibrin Gel Angiogenesis Bead Assay
  Methods in Molecular Biology (Clifton, N.J.). 2022  |   Pubmed ID: 35099748
• Coenzyme Q10 to Manage Chronic Heart Failure with a Reduced Ejection Fraction: a Systematic Review and Economic Evaluation
  Health Technology Assessment (Winchester, England). Jan, 2022  |   Pubmed ID: 35076012
• Hypoxia Signalling in the Regulation of Innate Immune Training
  Biochemical Society Transactions. Feb, 2022  |   Pubmed ID: 35015075
• Suboptimal Dosing of β-Blockers in Chronic Heart Failure: A Missed Opportunity?
  The Journal of Cardiovascular Nursing. Nov-Dec 01, 2022  |   Pubmed ID: 34321430
• Personalised Reprogramming to Prevent Progressive Pacemaker-related Left Ventricular Dysfunction: A Phase II Randomised, Controlled Clinical Trial
  PloS One. 2021  |   Pubmed ID: 34898655
• Causes of Death in People With Cardiovascular Disease: A UK Biobank Cohort Study
  Journal of the American Heart Association. Nov, 2021  |   Pubmed ID: 34743561
• Empagliflozin Treatment Is Associated With Improvements in Cardiac Energetics and Function and Reductions in Myocardial Cellular Volume in Patients With Type 2 Diabetes
  Diabetes. Dec, 2021  |   Pubmed ID: 34610982
• Pericyte Insulin Receptors Modulate Retinal Vascular Remodeling and Endothelial Angiopoietin Signaling
  Endocrinology. Nov, 2021  |   Pubmed ID: 34460911
• Novel Paracrine Action of Endothelium Enhances Glucose Uptake in Muscle and Fat
  Circulation Research. Sep, 2021  |   Pubmed ID: 34420367
• Impact of QRS Duration on Left Ventricular Remodelling and Survival in Patients with Heart Failure
  Journal of Cardiovascular Medicine (Hagerstown, Md.). Nov, 2021  |   Pubmed ID: 34261079
• Elimination of Fibrin γ-chain Cross-linking by FXIIIa Increases Pulmonary Embolism Arising from Murine Inferior Vena Cava Thrombi
  Proceedings of the National Academy of Sciences of the United States of America. 07, 2021  |   Pubmed ID: 34183396
• Endothelial Insulin Receptors Promote VEGF-A Signaling Via ERK1/2 and Sprouting Angiogenesis
  Endocrinology. Aug, 2021  |   Pubmed ID: 34037749
• Endothelial IGF-1 Receptor Mediates Crosstalk with the Gut Wall to Regulate Microbiota in Obesity
  EMBO Reports. May, 2021  |   Pubmed ID: 33934497
• Non-communicable Disease, Sociodemographic Factors, and Risk of Death from Infection: a UK Biobank Observational Cohort Study
  The Lancet. Infectious Diseases. Aug, 2021  |   Pubmed ID: 33662324
• Diabetes, Gender and Deterioration in Estimated Glomerular Filtration Rate in Patients with Chronic Heart Failure: Ten-year Prospective Cohort Study
  Diabetes & Vascular Disease Research. 2021  |   Pubmed ID: 33588611
• Advanced Care Planning During the COVID-19 Pandemic: Ceiling of Care Decisions and Their Implications for Observational Data
  BMC Palliative Care. Jan, 2021  |   Pubmed ID: 33430850
• Association of Heart Failure and Its Comorbidities with Loss of Life Expectancy
  Heart (British Cardiac Society). Sep, 2021  |   Pubmed ID: 33153996
• Dose-dependent Oral Glucocorticoid Cardiovascular Risks in People with Immune-mediated Inflammatory Diseases: A Population-based Cohort Study
  PLoS Medicine. Dec, 2020  |   Pubmed ID: 33270649
• Response by Gierula Et Al to Letter Regarding Article, "Personalized Rate-Response Programming Improves Exercise Tolerance After 6 Months in People With Cardiac Implantable Electronic Devices and Heart Failure: A Phase II Study"
  Circulation. Nov, 2020  |   Pubmed ID: 33166218
• Effect of Disease-modifying Agents and Their Association with Mortality in Multi-morbid Patients with Heart Failure with Reduced Ejection Fraction
  ESC Heart Failure. Dec, 2020  |   Pubmed ID: 32924331
• Unique Transcriptome Signature Distinguishes Patients With Heart Failure With Myopathy
  Journal of the American Heart Association. Sep, 2020  |   Pubmed ID: 32892688
• Prioritizing Symptom Management in the Treatment of Chronic Heart Failure
  ESC Heart Failure. Oct, 2020  |   Pubmed ID: 32757363
• Cardiovascular Mortality and Morbidity Following Radical Radiotherapy for Lung Cancer: Is Cardiovascular Death Under-reported?
  Lung Cancer (Amsterdam, Netherlands). Aug, 2020  |   Pubmed ID: 32460218
• Divergent Effects of Genetic and Pharmacological Inhibition of Nox2 NADPH Oxidase on Insulin Resistance-related Vascular Damage
  American Journal of Physiology. Cell Physiology. Jul, 2020  |   Pubmed ID: 32401607
• Infection-Related Hospitalization in Heart Failure With Reduced Ejection Fraction: A Prospective Observational Cohort Study
  Circulation. Heart Failure. May, 2020  |   Pubmed ID: 32354281
• Personalized Rate-Response Programming Improves Exercise Tolerance After 6 Months in People With Cardiac Implantable Electronic Devices and Heart Failure: A Phase II Study
  Circulation. May, 2020  |   Pubmed ID: 32299222
• IGFBP-1 in Cardiometabolic Pathophysiology-Insights From Loss-of-Function and Gain-of-Function Studies in Male Mice
  Journal of the Endocrine Society. Jan, 2020  |   Pubmed ID: 32190801
• Inorganic Nitrate Promotes Glucose Uptake and Oxidative Catabolism in White Adipose Tissue Through the XOR-Catalyzed Nitric Oxide Pathway
  Diabetes. May, 2020  |   Pubmed ID: 32086288
• Chronic Heart Failure with Diabetes Mellitus is Characterized by a Severe Skeletal Muscle Pathology
  Journal of Cachexia, Sarcopenia and Muscle. Apr, 2020  |   Pubmed ID: 31863644
• Divergent Skeletal Muscle Mitochondrial Phenotype Between Male and Female Patients with Chronic Heart Failure
  Journal of Cachexia, Sarcopenia and Muscle. Feb, 2020  |   Pubmed ID: 31430834
• Optimising Pacemaker Therapy and Medical Therapy in Pacemaker Patients for Heart Failure: Protocol for the OPT-PACE Randomised Controlled Trial
  BMJ Open. Jul, 2019  |   Pubmed ID: 31320354
• Predicting One-year Mortality in Heart Failure Using the 'Surprise Question': a Prospective Pilot Study
  European Journal of Heart Failure. Feb, 2019  |   Pubmed ID: 30548129
• Prognostic Significance of Incidental Nonsustained Ventricular Tachycardia Detected on Pacemaker Interrogation
  The American Journal of Cardiology. Feb, 2019  |   Pubmed ID: 30473328
• Prospective Evaluation and Long-term Follow-up of Patients Referred to Secondary Care Based Upon Natriuretic Peptide Levels in Primary Care
  European Heart Journal. Quality of Care & Clinical Outcomes. Jul, 2019  |   Pubmed ID: 30452611
• Effects of Obesity on Insulin: Insulin-like Growth Factor 1 Hybrid Receptor Expression and Akt Phosphorylation in Conduit and Resistance Arteries
  Diabetes & Vascular Disease Research. Mar, 2019  |   Pubmed ID: 30295509
• Vitamin D Deficiency is an Independent Predictor of Mortality in Patients with Chronic Heart Failure
  European Journal of Nutrition. Sep, 2019  |   Pubmed ID: 30121806
• Ischemic Heart Disease Modifies the Association of Atrial Fibrillation With Mortality in Heart Failure With Reduced Ejection Fraction
  Journal of the American Heart Association. Oct, 2018  |   Pubmed ID: 30371286
• Prevalence and Predictors of Sepsis Death in Patients With Chronic Heart Failure and Reduced Left Ventricular Ejection Fraction
  Journal of the American Heart Association. Oct, 2018  |   Pubmed ID: 30371261
• Role of Glutamine Synthetase in Angiogenesis Beyond Glutamine Synthesis
  Nature. Sep, 2018  |   Pubmed ID: 30158707
• Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection Via Redox Homeostasis
  Cell Metabolism. Dec, 2018  |   Pubmed ID: 30146488
• Endothelial Insulin Receptor Restoration Rescues Vascular Function in Male Insulin Receptor Haploinsufficient Mice
  Endocrinology. Aug, 2018  |   Pubmed ID: 29796592
• Homotypic Endothelial Nanotubes Induced by Wheat Germ Agglutinin and Thrombin
  Scientific Reports. May, 2018  |   Pubmed ID: 29765077
• Socioeconomic Deprivation and Mode-specific Outcomes in Patients with Chronic Heart Failure
  Heart (British Cardiac Society). Jun, 2018  |   Pubmed ID: 29386325
• Rate-Response Programming Tailored To the Force-Frequency Relationship Improves Exercise Tolerance in Chronic Heart Failure
  JACC. Heart Failure. Feb, 2018  |   Pubmed ID: 29226818
• Insulinlike Growth Factor-Binding Protein-1 Improves Vascular Endothelial Repair in Male Mice in the Setting of Insulin Resistance
  Endocrinology. Feb, 2018  |   Pubmed ID: 29186427
• Mortality Reduction Associated With β-Adrenoceptor Inhibition in Chronic Heart Failure Is Greater in Patients With Diabetes
  Diabetes Care. Jan, 2018  |   Pubmed ID: 28982651
• Piezo1 Channels Sense Whole Body Physical Activity to Reset Cardiovascular Homeostasis and Enhance Performance
  Nature Communications. 08, 2017  |   Pubmed ID: 28839146
• Endothelial SHIP2 Suppresses Nox2 NADPH Oxidase-Dependent Vascular Oxidative Stress, Endothelial Dysfunction, and Systemic Insulin Resistance
  Diabetes. Nov, 2017  |   Pubmed ID: 28830894
• Association Analyses Based on False Discovery Rate Implicate New Loci for Coronary Artery Disease
  Nature Genetics. Sep, 2017  |   Pubmed ID: 28714975
• Role of Glutamine and Interlinked Asparagine Metabolism in Vessel Formation
  The EMBO Journal. Aug, 2017  |   Pubmed ID: 28659375
• Insulin-Like Growth Factor Binding Protein 1 Could Improve Glucose Regulation and Insulin Sensitivity Through Its RGD Domain
  Diabetes. Feb, 2017  |   Pubmed ID: 28108607
• Selective Enhancement of Insulin Sensitivity in the Endothelium In Vivo Reveals a Novel Proatherosclerotic Signaling Loop
  Circulation Research. Mar, 2017  |   Pubmed ID: 27920123
• Pericytes in Diabetes-associated Vascular Disease
  Journal of Diabetes and Its Complications. 2016  |   Pubmed ID: 27592245
• Diabetes Mellitus is Associated with Adverse Structural and Functional Cardiac Remodelling in Chronic Heart Failure with Reduced Ejection Fraction
  Diabetes & Vascular Disease Research. Sep, 2016  |   Pubmed ID: 27334485
• Chronotropic Incompetence Does Not Limit Exercise Capacity in Chronic Heart Failure
  Journal of the American College of Cardiology. Apr, 2016  |   Pubmed ID: 27102504
• Effects of Vitamin D on Cardiac Function In Patients With Chronic HF: The VINDICATE Study
  Journal of the American College of Cardiology. Jun, 2016  |   Pubmed ID: 27058906
• Cardio-oncology: Concepts and Practice
  Indian Heart Journal. Apr, 2016  |   Pubmed ID: 27056658
• Performance of 2014 NICE Defibrillator Implantation Guidelines in Heart Failure Risk Stratification
  Heart (British Cardiac Society). May, 2016  |   Pubmed ID: 26857212
• Endothelial IGF-1 Receptor Signalling in Diabetes and Insulin Resistance
  Trends in Endocrinology and Metabolism: TEM. Feb, 2016  |   Pubmed ID: 26712712
• Ambulatory Heart Rate Range Predicts Mode-specific Mortality and Hospitalisation in Chronic Heart Failure
  Heart (British Cardiac Society). Feb, 2016  |   Pubmed ID: 26674986
• An Evaluation of 20 Year Survival in Patients with Diabetes Mellitus and Acute Myocardial Infarction
  International Journal of Cardiology. Jan, 2016  |   Pubmed ID: 26512829
• Sudden Cardiac Death in Patients with Diabetes Mellitus and Chronic Heart Failure
  Diabetes & Vascular Disease Research. Jul, 2015  |   Pubmed ID: 25861812
• Patients with Long-term Permanent Pacemakers Have a High Prevalence of Left Ventricular Dysfunction
  Journal of Cardiovascular Medicine (Hagerstown, Md.). Nov, 2015  |   Pubmed ID: 24979115
• Calcium, Phosphate and Calcium Phosphate Product Are Markers of Outcome in Patients with Chronic Heart Failure
  Journal of Nephrology. Apr, 2015  |   Pubmed ID: 24615401
• Contemporary Treatment Strategies for Type 2 Diabetes-related Macrovascular Disease
  Expert Review of Endocrinology & Metabolism. Nov, 2014  |   Pubmed ID: 30736201
• Piezo1 Integration of Vascular Architecture with Physiological Force
  Nature. Nov, 2014  |   Pubmed ID: 25119035
• Haploinsufficiency of the Insulin-like Growth Factor-1 Receptor Enhances Endothelial Repair and Favorably Modifies Angiogenic Progenitor Cell Phenotype
  Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2014  |   Pubmed ID: 25012136
• Restoring Akt1 Activity in Outgrowth Endothelial Cells from South Asian Men Rescues Vascular Reparative Potential
  Stem Cells (Dayton, Ohio). Oct, 2014  |   Pubmed ID: 24916783
• Pacing-associated Left Ventricular Dysfunction? Think Reprogramming First!
  Heart (British Cardiac Society). May, 2014  |   Pubmed ID: 24430095
• Endothelium-specific Insulin Resistance Leads to Accelerated Atherosclerosis in Areas with Disturbed Flow Patterns: a Role for Reactive Oxygen Species
  Atherosclerosis. Sep, 2013  |   Pubmed ID: 23958265
• Cardiac Resynchronization Therapy in Pacemaker-dependent Patients with Left Ventricular Dysfunction
  Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. Nov, 2013  |   Pubmed ID: 23736807
• Importance of Insulin Resistance to Vascular Repair and Regeneration
  Free Radical Biology & Medicine. Jul, 2013  |   Pubmed ID: 23466555
• Nox2 NADPH Oxidase Has a Critical Role in Insulin Resistance-related Endothelial Cell Dysfunction
  Diabetes. Jun, 2013  |   Pubmed ID: 23349484
• Diabetes Mellitus is Associated with Adverse Prognosis in Chronic Heart Failure of Ischaemic and Non-ischaemic Aetiology
  Diabetes & Vascular Disease Research. Jul, 2013  |   Pubmed ID: 23349368
• Moderate and Heavy Metabolic Stress Interval Training Improve Arterial Stiffness and Heart Rate Dynamics in Humans
  European Journal of Applied Physiology. Apr, 2013  |   Pubmed ID: 22983616
• Gender-specific Alterations in Fibrin Structure Function in Type 2 Diabetes: Associations with Cardiometabolic and Vascular Markers
  The Journal of Clinical Endocrinology and Metabolism. Dec, 2012  |   Pubmed ID: 22996148
• Novel Role of the IGF-1 Receptor in Endothelial Function and Repair: Studies in Endothelium-targeted IGF-1 Receptor Transgenic Mice
  Diabetes. Sep, 2012  |   Pubmed ID: 22733797
• Increasing Circulating IGFBP1 Levels Improves Insulin Sensitivity, Promotes Nitric Oxide Production, Lowers Blood Pressure, and Protects Against Atherosclerosis
  Diabetes. Apr, 2012  |   Pubmed ID: 22357965
• Insulin- and Growth Factor-resistance Impairs Vascular Regeneration in Diabetes Mellitus
  Current Vascular Pharmacology. May, 2012  |   Pubmed ID: 22239629
• Heavy and Moderate Interval Exercise Training Alters Low-flow-mediated Constriction but Does Not Increase Circulating Progenitor Cells in Healthy Humans
  Experimental Physiology. Mar, 2012  |   Pubmed ID: 22179420
• The Insulin-like Growth Factor-1 Receptor is a Negative Regulator of Nitric Oxide Bioavailability and Insulin Sensitivity in the Endothelium
  Diabetes. Aug, 2011  |   Pubmed ID: 21677284
• Changing Characteristics and Mode of Death Associated with Chronic Heart Failure Caused by Left Ventricular Systolic Dysfunction: a Study Across Therapeutic Eras
  Circulation. Heart Failure. Jul, 2011  |   Pubmed ID: 21562056
• Orai1 and CRAC Channel Dependence of VEGF-activated Ca2+ Entry and Endothelial Tube Formation
  Circulation Research. May, 2011  |   Pubmed ID: 21441136
• Insulin Resistance Impairs Circulating Angiogenic Progenitor Cell Function and Delays Endothelial Regeneration
  Diabetes. Apr, 2011  |   Pubmed ID: 21317296
• Human Exercise-induced Circulating Progenitor Cell Mobilization is Nitric Oxide-dependent and is Blunted in South Asian Men
  Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2010  |   Pubmed ID: 20110574
• Effects of Insulin Resistance on Endothelial Progenitor Cells and Vascular Repair
  Clinical Science (London, England : 1979). Aug, 2009  |   Pubmed ID: 19630751
• Vascular Insulin-like Growth Factor-I Resistance and Diet-induced Obesity
  Endocrinology. Oct, 2009  |   Pubmed ID: 19608653
• Cardiac Resynchronisation Therapy for Chronic Heart Failure and Conduction Delay
  BMJ (Clinical Research Ed.). Apr, 2009  |   Pubmed ID: 19401320
• Diabetes Mellitus and Mortality After Acute Coronary Syndrome As a First or Recurrent Cardiovascular Event
  PloS One. 2008  |   Pubmed ID: 18941531
• Aspirin and Mortality in Patients with Diabetes Sustaining Acute Coronary Syndrome
  Diabetes Care. Feb, 2008  |   Pubmed ID: 17959865
• The Impact of Insulin Resistance on Endothelial Function, Progenitor Cells and Repair
  Diabetes & Vascular Disease Research. Jun, 2007  |   Pubmed ID: 17654443