Robert A Edwards Department of Pathology UC Irvine Biography Publications Institution JoVE Articles Robert A Edwards has not added a biography. If you are Robert A Edwards and would like to personalize this page please email our Author Liaison for assistance. Publications Probiotic Bacteria Reduce Salmonella Typhimurium Intestinal Colonization by Competing for Iron Cell Host & Microbe. Jul, 2013 | Pubmed ID: 23870311 Circadian Clock Regulates the Host Response to Salmonella Proceedings of the National Academy of Sciences of the United States of America. Jun, 2013 | Pubmed ID: 23716692 Explaining Microbial Phenotypes on a Genomic Scale: GWAS for Microbes Briefings in Functional Genomics. Jul, 2013 | Pubmed ID: 23625995 Multivariate Analysis of Functional Metagenomes Frontiers in Genetics. 2013 | Pubmed ID: 23579547 Structure and Function of a Cyanophage-encoded Peptide Deformylase The ISME Journal. Jun, 2013 | Pubmed ID: 23407310 A Bioinformatic Analysis of Ribonucleotide Reductase Genes in Phage Genomes and Metagenomes BMC Evolutionary Biology. 2013 | Pubmed ID: 23391036 Applying Shannon's Information Theory to Bacterial and Phage Genomes and Metagenomes Scientific Reports. 2013 | Pubmed ID: 23301154 Intracellular Trafficking of the KV1.3 Potassium Channel is Regulated by the Prodomain of a Matrix Metalloprotease The Journal of Biological Chemistry. Mar, 2013 | Pubmed ID: 23300077 SEED Servers: High-performance Access to the SEED Genomes, Annotations, and Metabolic Models PloS One. 2012 | Pubmed ID: 23110173 Reference-independent Comparative Metagenomics Using Cross-assembly: CrAss Bioinformatics (Oxford, England). Dec, 2012 | Pubmed ID: 23074261 Real Time Metagenomics: Using K-mers to Annotate Metagenomes Bioinformatics (Oxford, England). Dec, 2012 | Pubmed ID: 23047562 Metabolic Trajectory of Cellular Differentiation in Small Intestine by Phasor Fluorescence Lifetime Microscopy of NADH Scientific Reports. 2012 | Pubmed ID: 22891156 Microfluidic PCR Combined with Pyrosequencing for Identification of Allelic Variants with Phenotypic Associations Among Targeted Salmonella Genes Applied and Environmental Microbiology. Oct, 2012 | Pubmed ID: 22885744 Sequencing of Seven Haloarchaeal Genomes Reveals Patterns of Genomic Flux PloS One. 2012 | Pubmed ID: 22848480 Taxonomic and Functional Microbial Signatures of the Endemic Marine Sponge Arenosclera Brasiliensis PloS One. 2012 | Pubmed ID: 22768320 Diversification of the Salmonella Fimbriae: a Model of Macro- and Microevolution PloS One. 2012 | Pubmed ID: 22701679 Genome-wide Study of the Defective Sucrose Fermenter Strain of Vibrio Cholerae from the Latin American Cholera Epidemic PloS One. 2012 | Pubmed ID: 22662140 MiR-23a Promotes the Transition from Indolent to Invasive Colorectal Cancer Cancer Discovery. Jun, 2012 | Pubmed ID: 22628407 PhiSpy: a Novel Algorithm for Finding Prophages in Bacterial Genomes That Combines Similarity- and Composition-based Strategies Nucleic Acids Research. Sep, 2012 | Pubmed ID: 22584627 Genome Sequences of the Ethanol-tolerant Lactobacillus Vini Strains LMG 23202T and JP7.8.9 Journal of Bacteriology. Jun, 2012 | Pubmed ID: 22582376 Genome Sequence of the Bacterioplanktonic, Mixotrophic Vibrio Campbellii Strain PEL22A, Isolated in the Abrolhos Bank Journal of Bacteriology. May, 2012 | Pubmed ID: 22535939 Muscle Sarcomas and Alopecia in A/J Mice Chronically Treated with Nicotine Life Sciences. Nov, 2012 | Pubmed ID: 22521759 Draft Genome Sequence of the Shrimp Pathogen Vibrio Harveyi CAIM 1792 Journal of Bacteriology. Apr, 2012 | Pubmed ID: 22461546 Zinc Sequestration by the Neutrophil Protein Calprotectin Enhances Salmonella Growth in the Inflamed Gut Cell Host & Microbe. Mar, 2012 | Pubmed ID: 22423963 PhiSiGns: an Online Tool to Identify Signature Genes in Phages and Design PCR Primers for Examining Phage Diversity BMC Bioinformatics. 2012 | Pubmed ID: 22385976 TNF-α Induces Up-Regulation of EGFR Expression and Signaling in Human Colonic Myofibroblasts American Journal of Physiology. Gastrointestinal and Liver Physiology. Feb, 2012 | Pubmed ID: 22301110 Characterization of the ELPhiS Prophage from Salmonella Enterica Serovar Enteritidis Strain LK5 Applied and Environmental Microbiology. Jan, 2012 | Pubmed ID: 22247173 PHACTS, a Computational Approach to Classifying the Lifestyle of Phages Bioinformatics (Oxford, England). Jan, 2012 | Pubmed ID: 22238260 Phage-bacteria Relationships and CRISPR Elements Revealed by a Metagenomic Survey of the Rumen Microbiome Environmental Microbiology. Jan, 2012 | Pubmed ID: 22004549 Genome Sequence of the Human Pathogen Vibrio Cholerae Amazonia Journal of Bacteriology. Oct, 2011 | Pubmed ID: 21952545 Cytokine-induced Alterations of α7 Nicotinic Receptor in Colonic CD4 T Cells Mediate Dichotomous Response to Nicotine in Murine Models of Th1/Th17- Versus Th2-mediated Colitis Journal of Immunology (Baltimore, Md. : 1950). Sep, 2011 | Pubmed ID: 21784975 Linking Lipid Metabolism to the Innate Immune Response in Macrophages Through Sterol Regulatory Element Binding Protein-1a Cell Metabolism. May, 2011 | Pubmed ID: 21531336 Mutation of NIMA-related Kinase 1 (NEK1) Leads to Chromosome Instability Molecular Cancer. 2011 | Pubmed ID: 21214959 Accessing the SEED Genome Databases Via Web Services API: Tools for Programmers BMC Bioinformatics. 2010 | Pubmed ID: 20546611 Transposases Are the Most Abundant, Most Ubiquitous Genes in Nature Nucleic Acids Research. Jul, 2010 | Pubmed ID: 20215432 Cancer Research. Feb, 2010 | Pubmed ID: 20145124 Bovine Serum Albumin Glutaraldehyde for Completely Sutureless Laparoscopic Heminephrectomy in a Survival Porcine Model Journal of Endourology / Endourological Society. Mar, 2010 | Pubmed ID: 20059350 Lysogeny and Sporulation in Bacillus Isolates from the Gulf of Mexico Applied and Environmental Microbiology. Feb, 2010 | Pubmed ID: 20008174 The GAAS Metagenomic Tool and Its Estimations of Viral and Microbial Average Genome Size in Four Major Biomes PLoS Computational Biology. Dec, 2009 | Pubmed ID: 20011103 Epigenetic Repression of DNA Mismatch Repair by Inflammation and Hypoxia in Inflammatory Bowel Disease-associated Colorectal Cancer Cancer Research. Aug, 2009 | Pubmed ID: 19638594 Metagenomic Analysis of Stressed Coral Holobionts Environmental Microbiology. Aug, 2009 | Pubmed ID: 19397678 Evaluation of the Outcomes of Electrosurgical Induced Bowel Injury Treated with Tissue Glue/sealant Versus Sutured Repair in a Rabbit Model Journal of Endourology / Endourological Society. Mar, 2009 | Pubmed ID: 19275489 The 'buoy' Stent: Evaluation of a Prototype Indwelling Ureteric Stent in a Porcine Model BJU International. Jul, 2009 | Pubmed ID: 19154469 Comparative Study of in Vivo Lymphatic Sealing Capability of the Porcine Thoracic Duct Using Laparoscopic Dissection Devices The Journal of Urology. Jan, 2009 | Pubmed ID: 19010491 Metagenomic Analysis Indicates That Stressors Induce Production of Herpes-like Viruses in the Coral Porites Compressa Proceedings of the National Academy of Sciences of the United States of America. Nov, 2008 | Pubmed ID: 19017800 Comparative Metagenomics Reveals Host Specific Metavirulomes and Horizontal Gene Transfer Elements in the Chicken Cecum Microbiome PloS One. 2008 | Pubmed ID: 18698407 Bone Marrow Stem Cells for Urologic Tissue Engineering World Journal of Urology. Aug, 2008 | Pubmed ID: 18654786 Taxonomic Composition and Gene Content of a Methane-producing Microbial Community Isolated from a Biogas Reactor Journal of Biotechnology. Aug, 2008 | Pubmed ID: 18611419 Viral Diversity and Dynamics in an Infant Gut Research in Microbiology. Jun, 2008 | Pubmed ID: 18541415 Viral Communities Associated with Healthy and Bleaching Corals Environmental Microbiology. Sep, 2008 | Pubmed ID: 18479440 Role for Epithelial Dysregulation in Early-onset Colitis-associated Colon Cancer in Gi2-alpha-/- Mice Inflammatory Bowel Diseases. Jul, 2008 | Pubmed ID: 18340649 Functional Metagenomic Profiling of Nine Biomes Nature. Apr, 2008 | Pubmed ID: 18337718 Comparison of Healing After Cystotomy and Repair with Fibrin Glue and Sutured Closure in the Porcine Model Journal of Endourology / Endourological Society. Jan, 2008 | Pubmed ID: 18315486 Biodiversity and Biogeography of Phages in Modern Stromatolites and Thrombolites Nature. Mar, 2008 | Pubmed ID: 18311127 Microbial Ecology of Four Coral Atolls in the Northern Line Islands PloS One. 2008 | Pubmed ID: 18301735 Phylogenetic Classification of Short Environmental DNA Fragments Nucleic Acids Research. Apr, 2008 | Pubmed ID: 18285365 The RAST Server: Rapid Annotations Using Subsystems Technology BMC Genomics. 2008 | Pubmed ID: 18261238 Bacterial Carbon Processing by Generalist Species in the Coastal Ocean Nature. Feb, 2008 | Pubmed ID: 18223640 Evidence for Differential Roles for NKG2D Receptor Signaling in Innate Host Defense Against Coronavirus-induced Neurological and Liver Disease Journal of Virology. Mar, 2008 | Pubmed ID: 18094157 Metagenomic and Small-subunit RRNA Analyses Reveal the Genetic Diversity of Bacteria, Archaea, Fungi, and Viruses in Soil Applied and Environmental Microbiology. Nov, 2007 | Pubmed ID: 17827313 Expression of CXC Chemokine Ligand 10 from the Mouse Hepatitis Virus Genome Results in Protection from Viral-induced Neurological and Liver Disease Journal of Immunology (Baltimore, Md. : 1950). Jul, 2007 | Pubmed ID: 17617609 Development of Indole Chemistry to Label Tryptophan Residues in Protein for Determination of Tryptophan Surface Accessibility Protein Science : a Publication of the Protein Society. Jun, 2007 | Pubmed ID: 17525468 Decreased MAPK- and PGE2-dependent IL-11 Production in Gialpha2-/- Colonic Myofibroblasts American Journal of Physiology. Gastrointestinal and Liver Physiology. Jun, 2007 | Pubmed ID: 17332478 The National Microbial Pathogen Database Resource (NMPDR): a Genomics Platform Based on Subsystem Annotation Nucleic Acids Research. Jan, 2007 | Pubmed ID: 17145713 The Marine Viromes of Four Oceanic Regions PLoS Biology. Nov, 2006 | Pubmed ID: 17090214 Finding Novel Genes in Bacterial Communities Isolated from the Environment Bioinformatics (Oxford, England). Jul, 2006 | Pubmed ID: 16873483 Identification of Trichloroethanol Visualized Proteins from Two-dimensional Polyacrylamide Gels by Mass Spectrometry Analytical Chemistry. Apr, 2006 | Pubmed ID: 16579625 Using Pyrosequencing to Shed Light on Deep Mine Microbial Ecology BMC Genomics. 2006 | Pubmed ID: 16549033 An Application of Statistics to Comparative Metagenomics BMC Bioinformatics. 2006 | Pubmed ID: 16549025 Differential Roles for CXCR3 in CD4+ and CD8+ T Cell Trafficking Following Viral Infection of the CNS European Journal of Immunology. Mar, 2006 | Pubmed ID: 16479546 Low-molecular-weight Protein Tyrosine Phosphatases of Bacillus Subtilis Journal of Bacteriology. Jul, 2005 | Pubmed ID: 15995210 Viral Metagenomics Nature Reviews. Microbiology. Jun, 2005 | Pubmed ID: 15886693 Impaired TGF-beta Responses in Peripheral T Cells of G Alpha I2-/- Mice Journal of Immunology (Baltimore, Md. : 1950). May, 2005 | Pubmed ID: 15879107 In Vitro Characterization of the Bacillus Subtilis Protein Tyrosine Phosphatase YwqE Journal of Bacteriology. May, 2005 | Pubmed ID: 15866923 Mosaic Prophages with Horizontally Acquired Genes Account for the Emergence and Diversification of the Globally Disseminated M1T1 Clone of Streptococcus Pyogenes Journal of Bacteriology. May, 2005 | Pubmed ID: 15866915 Robotic Radical Prostatectomy: a Technique to Reduce PT2 Positive Margins Urology. Dec, 2004 | Pubmed ID: 15596205 Visible Fluorescent Detection of Proteins in Polyacrylamide Gels Without Staining Analytical Biochemistry. Mar, 2004 | Pubmed ID: 14769330 Trp-999 of Beta-galactosidase (Escherichia Coli) is a Key Residue for Binding, Catalysis, and Synthesis of Allolactose, the Natural Lac Operon Inducer Biochemistry. Feb, 2003 | Pubmed ID: 12578395 The Light-induced Reactions of Tryptophan with Halocompounds Photochemistry and Photobiology. Apr, 2002 | Pubmed ID: 12003125 Comparative Genomics of Closely Related Salmonellae Trends in Microbiology. Feb, 2002 | Pubmed ID: 11827811 Visualization of Proteins in Acrylamide Gels Using Ultraviolet Illumination Analytical Biochemistry. Feb, 2002 | Pubmed ID: 11811971 Isolation of Primary Myofibroblasts from Mouse and Human Colon Tissue Hassan Khalil1, Wenxian Nie1, Robert A Edwards2, James Yoo1 1Department of Surgery, UCLA, 2Department of Pathology, UC Irvine JoVE 50611 Biology Laser Capture Microdissection of Mammalian Tissue Robert A Edwards1 1Department of Pathology, University of California, Irvine (UCI) Biology
Isolation of Primary Myofibroblasts from Mouse and Human Colon Tissue Hassan Khalil1, Wenxian Nie1, Robert A Edwards2, James Yoo1 1Department of Surgery, UCLA, 2Department of Pathology, UC Irvine JoVE 50611 Biology
Laser Capture Microdissection of Mammalian Tissue Robert A Edwards1 1Department of Pathology, University of California, Irvine (UCI) Biology