Robert P. Ryan Division of Molecular Microbiology, College of Life Sciences University of Dundee Biography Publications Institution JoVE Articles Robert P. Ryan has not added a biography. If you are Robert P. Ryan and would like to personalize this page please email our Author Liaison for assistance. Publications Combating Chronic Bacterial Infections by Manipulating Cyclic Nucleotide-regulated Biofilm Formation Future Medicinal Chemistry. Jun, 2016 | Pubmed ID: 27304227 Functional and Genomic Insights into the Pathogenesis of Burkholderia Species to Rice Environmental Microbiology. Mar, 2016 | Pubmed ID: 26690879 Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats Hypertension. Feb, 2016 | Pubmed ID: 26644237 The DSF Family of Cell-Cell Signals: An Expanding Class of Bacterial Virulence Regulators PLoS Pathogens. Jul, 2015 | Pubmed ID: 26181439 Structural Insights into the Distinct Binding Mode of Cyclic Di-AMP with SaCpaA_RCK Biochemistry. Aug, 2015 | Pubmed ID: 26171638 Haemophilus Influenzae Responds to Glucocorticoids Used in Asthma Therapy by Modulation of Biofilm Formation and Antibiotic Resistance EMBO Molecular Medicine. Aug, 2015 | Pubmed ID: 25995336 The Changing Face of Asthma and Its Relation with Microbes Trends in Microbiology. Jul, 2015 | Pubmed ID: 25840766 Null Mutation of the Nicotinamide Adenine Dinucleotide Phosphate-oxidase Subunit P67phox Protects the Dahl-S Rat from Salt-induced Reductions in Medullary Blood Flow and Glomerular Filtration Rate Hypertension. Mar, 2015 | Pubmed ID: 25489057 Targeting Cyclic Di-GMP Signalling: a Strategy to Control Biofilm Formation? Current Pharmaceutical Design. 2015 | Pubmed ID: 25189859 Novel Cyclic Di-GMP Effectors of the YajQ Protein Family Control Bacterial Virulence PLoS Pathogens. Oct, 2014 | Pubmed ID: 25329577 Communication, Cooperation, and Social Interactions: a Report from the Third Young Microbiologists Symposium on Microbe Signalling, Organisation, and Pathogenesis Journal of Bacteriology. Oct, 2014 | Pubmed ID: 25070739 Heterogeneity in Ess Transcriptional Organization and Variable Contribution of the Ess/Type VII Protein Secretion System to Virulence Across Closely Related Staphylocccus Aureus Strains Molecular Microbiology. Sep, 2014 | Pubmed ID: 25040609 Polybacterial Human Disease: the Ills of Social Networking Trends in Microbiology. Sep, 2014 | Pubmed ID: 24938173 The PAS Domain-containing Histidine Kinase RpfS is a Second Sensor for the Diffusible Signal Factor of Xanthomonas Campestris Molecular Microbiology. May, 2014 | Pubmed ID: 24617591 Crystal Structure of an HD-GYP Domain Cyclic-di-GMP Phosphodiesterase Reveals an Enzyme with a Novel Trinuclear Catalytic Iron Centre Molecular Microbiology. Jan, 2014 | Pubmed ID: 24176013 Microbiota and Metabolite Profiling Reveal Specific Alterations in Bacterial Community Structure and Environment in the Cystic Fibrosis Airway During Exacerbation PloS One. 2013 | Pubmed ID: 24358183 Genomic Survey of Pathogenicity Determinants and VNTR Markers in the Cassava Bacterial Pathogen Xanthomonas Axonopodis Pv. Manihotis Strain CIO151 PloS One. 2013 | Pubmed ID: 24278159 A Cyclic GMP-dependent Signalling Pathway Regulates Bacterial Phytopathogenesis The EMBO Journal. Sep, 2013 | Pubmed ID: 23881098 Proteomics Analysis of the Regulatory Role of Rpf/DSF Cell-to-cell Signaling System in the Virulence of Xanthomonas Campestris Molecular Plant-microbe Interactions : MPMI. Oct, 2013 | Pubmed ID: 23819805 Cyclic Di-GMP Signalling and the Regulation of Bacterial Virulence Microbiology (Reading, England). Jul, 2013 | Pubmed ID: 23704785 Progression of Glomerular Filtration Rate Reduction Determined in Conscious Dahl Salt-sensitive Hypertensive Rats Hypertension. Jul, 2013 | Pubmed ID: 23630946 High-resolution Transcriptional Analysis of the Regulatory Influence of Cell-to-cell Signalling Reveals Novel Genes That Contribute to Xanthomonas Phytopathogenesis Molecular Microbiology. Jun, 2013 | Pubmed ID: 23617851 Real-time Electrochemical Detection of ATP and H₂O₂ Release in Freshly Isolated Kidneys American Journal of Physiology. Renal Physiology. Jul, 2013 | Pubmed ID: 23594827 Comparative Transcriptomic Analysis of the Burkholderia Cepacia Tyrosine Kinase BceF Mutant Reveals a Role in Tolerance to Stress, Biofilm Formation, and Virulence Applied and Environmental Microbiology. May, 2013 | Pubmed ID: 23435894 The Exopolysaccharide Gene Cluster Bcam1330-Bcam1341 is Involved in Burkholderia Cenocepacia Biofilm Formation, and Its Expression is Regulated by C-di-GMP and Bcam1349 MicrobiologyOpen. Feb, 2013 | Pubmed ID: 23281338 Increased Proliferative Cells in the Medullary Thick Ascending Limb of the Loop of Henle in the Dahl Salt-sensitive Rat Hypertension. Jan, 2013 | Pubmed ID: 23184381 RsmA Regulates Biofilm Formation in Xanthomonas Campestris Through a Regulatory Network Involving Cyclic Di-GMP and the Clp Transcription Factor PloS One. 2012 | Pubmed ID: 23285129 Modelling Co-infection of the Cystic Fibrosis Lung by Pseudomonas Aeruginosa and Burkholderia Cenocepacia Reveals Influences on Biofilm Formation and Host Response PloS One. 2012 | Pubmed ID: 23284990 Socializing, Networking and Development: a Report from the Second 'Young Microbiologists Symposium on Microbe Signalling, Organization and Pathogenesis' Molecular Microbiology. Nov, 2012 | Pubmed ID: 22934780 Dynamic Complex Formation Between HD-GYP, GGDEF and PilZ Domain Proteins Regulates Motility in Xanthomonas Campestris Molecular Microbiology. Nov, 2012 | Pubmed ID: 22924852 Mitochondrial Proteomic Analysis Reveals Deficiencies in Oxygen Utilization in Medullary Thick Ascending Limb of Henle in the Dahl Salt-sensitive Rat Physiological Genomics. Sep, 2012 | Pubmed ID: 22805345 When the PilZ Don't Work: Effectors for Cyclic Di-GMP Action in Bacteria Trends in Microbiology. May, 2012 | Pubmed ID: 22444828 Increase of Sodium Delivery Stimulates the Mitochondrial Respiratory Chain H2O2 Production in Rat Renal Medullary Thick Ascending Limb American Journal of Physiology. Renal Physiology. Jan, 2012 | Pubmed ID: 21975873 Bacterial Cis-2-unsaturated Fatty Acids Found in the Cystic Fibrosis Airway Modulate Virulence and Persistence of Pseudomonas Aeruginosa The ISME Journal. Dec, 2011 | Pubmed ID: 22134647 The Ax21 Protein is a Cell-cell Signal That Regulates Virulence in the Nosocomial Pathogen Stenotrophomonas Maltophilia Journal of Bacteriology. Nov, 2011 | Pubmed ID: 21908663 The CRP/FNR Family Protein Bcam1349 is a C-di-GMP Effector That Regulates Biofilm Formation in the Respiratory Pathogen Burkholderia Cenocepacia Molecular Microbiology. Oct, 2011 | Pubmed ID: 21883527 Two New Complete Genome Sequences Offer Insight into Host and Tissue Specificity of Plant Pathogenic Xanthomonas Spp Journal of Bacteriology. Oct, 2011 | Pubmed ID: 21784931 Advances in Bacterial Transcriptome and Transposon Insertion-site Profiling Using Second-generation Sequencing Trends in Biotechnology. Nov, 2011 | Pubmed ID: 21764162 Pathogenomics of Xanthomonas: Understanding Bacterium-plant Interactions Nature Reviews. Microbiology. May, 2011 | Pubmed ID: 21478901 NSAIDs Acutely Inhibit TRPC Channels in Freshly Isolated Rat Glomeruli Biochemical and Biophysical Research Communications. May, 2011 | Pubmed ID: 21473850 Comparative Genomics Reveals Diversity Among Xanthomonads Infecting Tomato and Pepper BMC Genomics. 2011 | Pubmed ID: 21396108 Comparison of Corticotropin-releasing Factor, Dexamethasone, and Temozolomide: Treatment Efficacy and Toxicity in U87 and C6 Intracranial Gliomas Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2011 | Pubmed ID: 21385926 Communication with a Growing Family: Diffusible Signal Factor (DSF) Signaling in Bacteria Trends in Microbiology. Mar, 2011 | Pubmed ID: 21227698 Corticorelin Acetate, a Synthetic Corticotropin-releasing Factor with Preclinical Antitumor Activity, Alone and with Bevacizumab, Against Human Solid Tumor Models Cancer Chemotherapy and Pharmacology. Jun, 2011 | Pubmed ID: 20809121 Corticorelin Acetate, a Synthetic Corticotropin-releasing Factor with Preclinical Antitumor Activity, Alone and with Bevacizumab, Against Human Brain Tumor Models Anticancer Research. Dec, 2010 | Pubmed ID: 21187487 Intermolecular Interactions Between HD-GYP and GGDEF Domain Proteins Mediate Virulence-related Signal Transduction in Xanthomonas Campestris Virulence. Sep-Oct, 2010 | Pubmed ID: 21178479 Protective Effect of Lifor Solution in Experimental Renal Ischemia-reperfusion Injury The Journal of Surgical Research. Dec, 2010 | Pubmed ID: 20888590 A Sensor Kinase Recognizing the Cell-cell Signal BDSF (cis-2-dodecenoic Acid) Regulates Virulence in Burkholderia Cenocepacia Molecular Microbiology. Sep, 2010 | Pubmed ID: 20624216 Cell-cell Signal-dependent Dynamic Interactions Between HD-GYP and GGDEF Domain Proteins Mediate Virulence in Xanthomonas Campestris Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010 | Pubmed ID: 20231439 The CAMP Receptor-like Protein CLP is a Novel C-di-GMP Receptor Linking Cell-cell Signaling to Virulence Gene Expression in Xanthomonas Campestris Journal of Molecular Biology. Feb, 2010 | Pubmed ID: 20004667 Passing GO (gene Ontology) in Plant Pathogen Biology: a Report from the Xanthomonas Genomics Conference Cellular Microbiology. Dec, 2009 | Pubmed ID: 19804485 Nurturing Scientific Mutualism: a Report from the 'Young Microbiologists Mini-Symposium on Microbe Signalling, Organisation and Pathogenesis' Molecular Microbiology. Sep, 2009 | Pubmed ID: 19656292 The Versatility and Adaptation of Bacteria from the Genus Stenotrophomonas Nature Reviews. Microbiology. Jul, 2009 | Pubmed ID: 19528958 Intraspecies Signaling Involving the Diffusible Signal Factor BDSF (cis-2-dodecenoic Acid) Influences Virulence in Burkholderia Cenocepacia Journal of Bacteriology. Aug, 2009 | Pubmed ID: 19482924 HD-GYP Domain Proteins Regulate Biofilm Formation and Virulence in Pseudomonas Aeruginosa Environmental Microbiology. May, 2009 | Pubmed ID: 19170727 Protective Effect of 20-HETE Analogues in Experimental Renal Ischemia Reperfusion Injury Kidney International. Mar, 2009 | Pubmed ID: 19052533 Acquisition and Evolution of Plant Pathogenesis-associated Gene Clusters and Candidate Determinants of Tissue-specificity in Xanthomonas PloS One. 2008 | Pubmed ID: 19043590 The Role of PilZ Domain Proteins in the Virulence of Xanthomonas Campestris Pv. Campestris Molecular Plant Pathology. Nov, 2008 | Pubmed ID: 19019010 Transfer of the CYP4A Region of Chromosome 5 from Lewis to Dahl S Rats Attenuates Renal Injury American Journal of Physiology. Renal Physiology. Dec, 2008 | Pubmed ID: 18842817 Diffusible Signals and Interspecies Communication in Bacteria Microbiology (Reading, England). Jul, 2008 | Pubmed ID: 18599814 Genome Sequence and Rapid Evolution of the Rice Pathogen Xanthomonas Oryzae Pv. Oryzae PXO99A BMC Genomics. 2008 | Pubmed ID: 18452608 Interspecies Signalling Via the Stenotrophomonas Maltophilia Diffusible Signal Factor Influences Biofilm Formation and Polymyxin Tolerance in Pseudomonas Aeruginosa Molecular Microbiology. Apr, 2008 | Pubmed ID: 18312265 Bacterial Endophytes: Recent Developments and Applications FEMS Microbiology Letters. Jan, 2008 | Pubmed ID: 18034833 Diffusible Signal Factor-dependent Cell-cell Signaling and Virulence in the Nosocomial Pathogen Stenotrophomonas Maltophilia Journal of Bacteriology. Jul, 2007 | Pubmed ID: 17468254 An Acquired Efflux System is Responsible for Copper Resistance in Xanthomonas Strain IG-8 Isolated from China FEMS Microbiology Letters. Mar, 2007 | Pubmed ID: 17263848 Cyclic Di-GMP Signalling in the Virulence and Environmental Adaptation of Xanthomonas Campestris Molecular Microbiology. Jan, 2007 | Pubmed ID: 17241199 Elevations in Renal Interstitial Hydrostatic Pressure and 20-hydroxyeicosatetraenoic Acid Contribute to Pressure Natriuresis Hypertension. Mar, 2007 | Pubmed ID: 17210834 The HD-GYP Domain, Cyclic Di-GMP Signaling, and Bacterial Virulence to Plants Molecular Plant-microbe Interactions : MPMI. Dec, 2006 | Pubmed ID: 17153922 Cyclic Di-GMP Signaling in Bacteria: Recent Advances and New Puzzles Journal of Bacteriology. Dec, 2006 | Pubmed ID: 17028282 Cell-cell Signaling, Cyclic Di-GMP Turnover and Regulation of Virulence in Xanthomonas Campestris Research in Microbiology. Dec, 2006 | Pubmed ID: 17008065 Cell-cell Signaling in Xanthomonas Campestris Involves an HD-GYP Domain Protein That Functions in Cyclic Di-GMP Turnover Proceedings of the National Academy of Sciences of the United States of America. Apr, 2006 | Pubmed ID: 16611728 Identification of a QTL on Chromosome 1 for Impaired Autoregulation of RBF in Fawn-hooded Hypertensive Rats American Journal of Physiology. Renal Physiology. May, 2006 | Pubmed ID: 16303858 Inrättandet av en hög kapacitet Setup för screening av små molekyler som modulerar c-di-GMP Signalering i Kushal N. Rugjee1, Shi-qi An1, Robert P. Ryan1 1Division of Molecular Microbiology, College of Life Sciences, University of Dundee JoVE 54115 Immunology and Infection
Inrättandet av en hög kapacitet Setup för screening av små molekyler som modulerar c-di-GMP Signalering i Kushal N. Rugjee1, Shi-qi An1, Robert P. Ryan1 1Division of Molecular Microbiology, College of Life Sciences, University of Dundee JoVE 54115 Immunology and Infection