Santiago Lima

Publications

• Targeting Defective Sphingosine Kinase 1 in Niemann-Pick Type C Disease with an Activator Mitigates Cholesterol Accumulation
  The Journal of Biological Chemistry. 07, 2020  |   Pubmed ID: 32385114
• A Simple Method for Sphingolipid Analysis of Tissues Embedded in Optimal Cutting Temperature Compound
  Journal of Lipid Research. 06, 2020  |   Pubmed ID: 32341007
• Influence of Nonprotective Autophagy and the Autophagic Switch on Sensitivity to Cisplatin in Non-small Cell Lung Cancer Cells
  Biochemical Pharmacology. 05, 2020  |   Pubmed ID: 32135156
• Design of New Quinolin-2-one-pyrimidine Hybrids As Sphingosine Kinases Inhibitors
  Bioorganic Chemistry. 01, 2020  |   Pubmed ID: 31757412
• Synthesis and Biological Evaluation of Sphingosine Kinase 2 Inhibitors with Anti-inflammatory Activity
  Archiv Der Pharmazie. Mar, 2019  |   Pubmed ID: 30648282
• Differential Radiation Sensitivity in P53 Wild-Type and P53-Deficient Tumor Cells Associated with Senescence but Not Apoptosis or (Nonprotective) Autophagy
  Radiation Research. 11, 2018  |   Pubmed ID: 30132722
• ABCC1-Exported Sphingosine-1-phosphate, Produced by Sphingosine Kinase 1, Shortens Survival of Mice and Patients with Breast Cancer
  Molecular Cancer Research : MCR. Jun, 2018  |   Pubmed ID: 29523764
• TP53 is Required for BECN1- and ATG5-dependent Cell Death Induced by Sphingosine Kinase 1 Inhibition
  Autophagy. 2018  |   Pubmed ID: 29368980
• An Integrative Study to Identify Novel Scaffolds for Sphingosine Kinase 1 Inhibitors
  European Journal of Medicinal Chemistry. Oct, 2017  |   Pubmed ID: 28822281
• Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking
  The Journal of Biological Chemistry. 02, 2017  |   Pubmed ID: 28049734
• Revisiting the Sphingolipid Rheostat: Evolving Concepts in Cancer Therapy
  Experimental Cell Research. May, 2015  |   Pubmed ID: 25770011
• Role of Sphingosine Kinase 1 and Sphingosine-1-phosphate in CD40 Signaling and IgE Class Switching
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2014  |   Pubmed ID: 25002116
• A Real-time High-throughput Fluorescence Assay for Sphingosine Kinases
  Journal of Lipid Research. 07, 2014  |   Pubmed ID: 24792926
• Sphingosine Kinase: a Closer Look at Last
  Structure (London, England : 1993). May, 2013  |   Pubmed ID: 23664359