Shin Aoki Faculty of Pharmaceutical Sciences Tokyo University of Science Biography Publications Institution JoVE Articles Shin Aoki has not added a biography. If you are Shin Aoki and would like to personalize this page please email our Author Liaison for assistance. Publications Stereospecific Synthesis of Tris-heteroleptic Tris-cyclometalated Iridium(III) Complexes Via Different Heteroleptic Halogen-Bridged Iridium(III) Dimers and Their Photophysical Properties Inorganic Chemistry. Apr, 2018 | Pubmed ID: 29611703 Increased Diversity with Reduced "diversity Evenness" of Tumor Infiltrating T-cells for the Successful Cancer Immunotherapy Scientific Reports. Jan, 2018 | Pubmed ID: 29348598 Size-Based Differentiation of Cancer and Normal Cells by a Particle Size Analyzer Assisted by a Cell-Recognition PC Software Biological & Pharmaceutical Bulletin. Apr, 2018 | Pubmed ID: 29332929 A Chemical Modulator of P53 Transactivation That Acts As a Radioprotective Agonist Molecular Cancer Therapeutics. Feb, 2018 | Pubmed ID: 28939557 Synthesis of Disaccharide Nucleosides Utilizing the Temporary Protection of the 2',3'-cis-Diol of Ribonucleosides by a Boronic Ester Molecules (Basel, Switzerland). Oct, 2017 | Pubmed ID: 28974027 Concise and Versatile Synthesis of Sulfoquinovosyl Acyl Glycerol Derivatives for Biological Applications Chemical & Pharmaceutical Bulletin. 2017 | Pubmed ID: 28566649 Efficient Synthesis of Tris-Heteroleptic Iridium(III) Complexes Based on the Zn-Promoted Degradation of Tris-Cyclometalated Iridium(III) Complexes and Their Photophysical Properties Inorganic Chemistry. Jan, 2017 | Pubmed ID: 28036181 Design and Synthesis of Tris-Heteroleptic Cyclometalated Iridium(III) Complexes Consisting of Three Different Nonsymmetric Ligands Based on Ligand-Selective Electrophilic Reactions Via Interligand HOMO Hopping Phenomena Inorganic Chemistry. Jan, 2017 | Pubmed ID: 28035836 Cationic Amphiphilic Tris-Cyclometalated Iridium(III) Complexes Induce Cancer Cell Death Via Interaction with Ca-Calmodulin Complex Bioconjugate Chemistry. 02, 2017 | Pubmed ID: 28032992 Supramolecular Complexes Formed by the Self-assembly of Hydrophobic Bis(Zn(2+)-cyclen) Complexes, Copper, and Di- or Triimide Units for the Hydrolysis of Phosphate Mono- and Diesters in Two-Phase Solvent Systems (Cyclen=1,4,7,10-Tetraazacyclododecane) Chemical & Pharmaceutical Bulletin. 2016 | Pubmed ID: 27150477 Development of a Novel Sulfonate Ester-based Prodrug Strategy Bioorganic & Medicinal Chemistry Letters. Jan, 2016 | Pubmed ID: 26642767 Enrichment of Circulating Tumor Cells in Tumor-bearing Mouse Blood by a Deterministic Lateral Displacement Microfluidic Device Biomedical Microdevices. 2015 | Pubmed ID: 26002773 Photochemical Properties of Red-Emitting Tris(cyclometalated) Iridium(III) Complexes Having Basic and Nitro Groups and Application to PH Sensing and Photoinduced Cell Death Inorganic Chemistry. Jun, 2015 | Pubmed ID: 25978770 Design and Synthesis of Amphiphilic and Luminescent Tris-Cyclometalated Iridium(III) Complexes Containing Cationic Peptides As Inducers and Detectors of Cell Death Via a Calcium-Dependent Pathway Bioconjugate Chemistry. May, 2015 | Pubmed ID: 25875312 Synthesis of Disaccharide Nucleosides by the O-glycosylation of Natural Nucleosides with Thioglycoside Donors Chemistry, an Asian Journal. Mar, 2015 | Pubmed ID: 25677492 Supramolecular Phosphatases Formed by the Self-assembly of the Bis(Zn²⁺-cyclen) Complex, Copper(II), and Barbital Derivatives in Water Chemistry, an Asian Journal. Oct, 2014 | Pubmed ID: 25080369 AS-2, a Novel Inhibitor of P53-dependent Apoptosis, Prevents Apoptotic Mitochondrial Dysfunction in a Transcription-independent Manner and Protects Mice from a Lethal Dose of Ionizing Radiation Biochemical and Biophysical Research Communications. Aug, 2014 | Pubmed ID: 25026551 Design and Synthesis of 8-hydroxyquinoline-based Radioprotective Agents Bioorganic & Medicinal Chemistry. Aug, 2014 | Pubmed ID: 25002230 Design, Synthesis and Photochemical Reactivation of Caged Prodrugs of 8-hydroxyquinoline-based Enzyme Inhibitors Chemical & Pharmaceutical Bulletin. 2014 | Pubmed ID: 24990501 Design and Synthesis of Chiral Zn2+ Complexes Mimicking Natural Aldolases for Catalytic C-C Bond Forming Reactions in Aqueous Solution International Journal of Molecular Sciences. Jan, 2014 | Pubmed ID: 24481060 Synthesis and Photochemical Properties of PH Responsive Tris-cyclometalated Iridium(III) Complexes That Contain a Pyridine Ring on the 2-phenylpyridine Ligand Inorganic Chemistry. Jan, 2014 | Pubmed ID: 24341415 Evaluation of Zinc (II) Chelators for Inhibiting P53-mediated Apoptosis Oncotarget. Dec, 2013 | Pubmed ID: 24280450 Design and Synthesis of a Luminescent Cyclometalated Iridium(III) Complex Having N,N-diethylamino Group That Stains Acidic Intracellular Organelles and Induces Cell Death by Photoirradiation Inorganic Chemistry. Dec, 2012 | Pubmed ID: 23145911 Selective Capture and Collection of Live Target Cells Using a Photoreactive Silicon Wafer Device Modified with Antibodies Via a Photocleavable Linker Langmuir : the ACS Journal of Surfaces and Colloids. Sep, 2012 | Pubmed ID: 22889078 Molecular Recognition of Hydrocarbon Guests by a Supramolecular Capsule Formed by the 4:4 Self-assembly of Tris(Zn(2+)-cyclen) and Trithiocyanurate in Aqueous Solution Chemistry, an Asian Journal. May, 2012 | Pubmed ID: 22311622 Potent Inhibition of Dinuclear Zinc(II) Peptidase, an Aminopeptidase from Aeromonas Proteolytica, by 8-quinolinol Derivatives: Inhibitor Design Based on Zn2+ Fluorophores, Kinetic, and X-ray Crystallographic Study Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Apr, 2012 | Pubmed ID: 22311113 One-pot Chemoenzymatic Synthesis of Chiral 1,3-diols Using an Enantioselective Aldol Reaction with Chiral Zn2+ Complex Catalysts and Enzymatic Reduction Using Oxidoreductases with Cofactor Regeneration Chemistry, an Asian Journal. Jan, 2012 | Pubmed ID: 22174123 Photochemical Cleavage Reaction of 8-quinolinyl Sulfonates That Are Halogenated and Nitrated at the 7-position Chemical & Pharmaceutical Bulletin. 2011 | Pubmed ID: 22041071 11B NMR Sensing of D-block Metal Ions in Vitro and in Cells Based on the Carbon-boron Bond Cleavage of Phenylboronic Acid-pendant Cyclen (cyclen = 1,4,7,10-tetraazacyclododecane) Inorganic Chemistry. Nov, 2011 | Pubmed ID: 22010826 Selective Hydrolysis of Phosphate Monoester by a Supramolecular Phosphatase Formed by the Self-assembly of a Bis(Zn(2+)-cyclen) Complex, Cyanuric Acid, and Copper in an Aqueous Solution (cyclen = 1,4,7,10-tetraazacyclododecane) Inorganic Chemistry. Oct, 2011 | Pubmed ID: 21936489 Regioselective Aromatic Substitution Reactions of Cyclometalated Ir(III) Complexes: Synthesis and Photochemical Properties of Substituted Ir(III) Complexes That Exhibit Blue, Green, and Red Color Luminescence Emission Inorganic Chemistry. Feb, 2011 | Pubmed ID: 21214169 Molecular Recognition of Inositol 1,4,5-trisphosphate and Model Compounds in Aqueous Solution by Ditopic Zn(2+) Complexes Containing Chiral Linkers Inorganic Chemistry. Jun, 2010 | Pubmed ID: 20420391 Sodium Orthovanadate Inhibits P53-mediated Apoptosis Cancer Research. Jan, 2010 | Pubmed ID: 20048077 Design and Synthesis of a Fluorescent Probe for Zn2+, 5,7-bis(N,N-dimethylaminosulfonyl)-8-hydroxyquinoline-pendant 1,4,7,10-tetraazacyclododecane and Zn2+-dependent Hydrolytic and Zn2+-independent Photochemical Reactivation of Its Benzenesulfonyl-caged Derivative Inorganic Chemistry. Feb, 2010 | Pubmed ID: 20039701 Photochemical Cleavage Reactions of 8-quinolinyl Sulfonates in Aqueous Solution Chemical & Pharmaceutical Bulletin. Nov, 2009 | Pubmed ID: 19881278 Chiral Catalysts Dually Functionalized with Amino Acid and Zn2+ Complex Components for Enantioselective Direct Aldol Reactions Inspired by Natural Aldolases: Design, Synthesis, Complexation Properties, Catalytic Activities, and Mechanistic Study Chemistry (Weinheim an Der Bergstrasse, Germany). Oct, 2009 | Pubmed ID: 19746465 Design and Synthesis of a Stable Supramolecular Trigonal Prism Formed by the Self-assembly of a Linear Tetrakis(Zn2+-cyclen) Complex and Trianionic Trithiocyanuric Acid in Aqueous Solution and Its Complexation with DNA (cyclen = 1,4,7,10-tetraazacyclododecane) Inorganic Chemistry. Oct, 2009 | Pubmed ID: 19743814 Design and Synthesis of a Photocleavable Biotin-linker for the Photoisolation of Ligand-receptor Complexes Based on the Photolysis of 8-quinolinyl Sulfonates in Aqueous Solution Bioorganic & Medicinal Chemistry. May, 2009 | Pubmed ID: 19362845 Photolysis of the Sulfonamide Bond of Metal Complexes of N-dansyl-1,4,7,10-tetraazacyclododecane in Aqueous Solution: a Mechanistic Study and Application to the Photorepair of Cis,syn-cyclobutane Thymine Photodimer Chemistry, an Asian Journal. Apr, 2009 | Pubmed ID: 19165842 BODIPY-based Fluorescent Redox Potential Sensors That Utilize Reversible Redox Properties of Flavin Chembiochem : a European Journal of Chemical Biology. Apr, 2008 | Pubmed ID: 18338353 Design and Synthesis of a Caged Zn2+ Probe, 8-benzenesulfonyloxy-5-N,N-dimethylaminosulfonylquinolin-2-ylmethyl-pendant 1,4,7,10-tetraazacyclododecane, and Its Hydrolytic Uncaging Upon Complexation with Zn2+ Inorganic Chemistry. Apr, 2008 | Pubmed ID: 18321042 A New Fluorescent Probe for Zinc(II): an 8-hydroxy-5-N,N-dimethylaminosulfonylquinoline-pendant 1,4,7,10-tetraazacyclododecane Chemistry (Weinheim an Der Bergstrasse, Germany). Dec, 2006 | Pubmed ID: 16953498 Efficient Cycloreversion of Cis,syn-thymine Photodimer by a Zn2+ -1,4,7,10-tetraazacyclododecane Complex Bearing a Lumiflavin and Tryptophan by Chemical Reduction and Photoreduction of a Lumiflavin Unit Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Nov, 2006 | Pubmed ID: 16944231 A Luminescence Sensor of Inositol 1,4,5-triphosphate and Its Model Compound by Ruthenium-templated Assembly of a Bis(Zn2+-cyclen) Complex Having a 2,2'-bipyridyl Linker (cyclen = 1,4,7,10-tetraazacyclododecane) Journal of the American Chemical Society. Jun, 2005 | Pubmed ID: 15969591 Metal Chelation-controlled Twisted Intramolecular Charge Transfer and Its Application to Fluorescent Sensing of Metal Ions and Anions Journal of the American Chemical Society. Oct, 2004 | Pubmed ID: 15479094 Zinc-nucleic Acid Interaction Chemical Reviews. Feb, 2004 | Pubmed ID: 14871140 Regioselective O- גליקוזילציה של נוקלאוזידים via זמני 2', 3'-Diol הגנה על ידי אסתר Boronic לסינתזה של דו-סוכר נוקלאוזידים Hidehisa Someya1, Taiki Itoh1, Mebae Kato1, Shin Aoki1,2 1Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2Imaging Frontier Center, Tokyo University of Science JoVE 57897 Chemistry
Regioselective O- גליקוזילציה של נוקלאוזידים via זמני 2', 3'-Diol הגנה על ידי אסתר Boronic לסינתזה של דו-סוכר נוקלאוזידים Hidehisa Someya1, Taiki Itoh1, Mebae Kato1, Shin Aoki1,2 1Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2Imaging Frontier Center, Tokyo University of Science JoVE 57897 Chemistry