Stephen B. McMahon Neurorestoration, Wolfson Centre for Age-Related Diseases King's College London Biography Publications Institution JoVE Articles Stephen B. McMahon has not added a biography. If you are Stephen B. McMahon and would like to personalize this page please email our Author Liaison for assistance. Publications Defining the Nociceptor Transcriptome Frontiers in Molecular Neuroscience. 2014 | Pubmed ID: 25426020 Null Mutation in SCN9A in Which Noxious Stimuli Can Be Detected in the Absence of Pain Neurology. Oct, 2014 | Pubmed ID: 25253744 Genome-wide Transcriptional Profiling of Skin and Dorsal Root Ganglia After Ultraviolet-B-induced Inflammation PloS One. 2014 | Pubmed ID: 24732968 Molecular Mechanisms Underlying the Enhanced Analgesic Effect of Oxycodone Compared to Morphine in Chemotherapy-induced Neuropathic Pain PloS One. 2014 | Pubmed ID: 24618941 Botulinum Toxin-A Treatment Reduces Human Mechanical Pain Sensitivity and Mechanotransduction Annals of Neurology. Apr, 2014 | Pubmed ID: 24550077 Pain Vulnerability: a Neurobiological Perspective Nature Neuroscience. Feb, 2014 | Pubmed ID: 24473267 A Comparison of RNA-seq and Exon Arrays for Whole Genome Transcription Profiling of the L5 Spinal Nerve Transection Model of Neuropathic Pain in the Rat Molecular Pain. 2014 | Pubmed ID: 24472155 Opening Paths to Novel Analgesics: the Role of Potassium Channels in Chronic Pain Trends in Neurosciences. Mar, 2014 | Pubmed ID: 24461875 Kv2 Dysfunction After Peripheral Axotomy Enhances Sensory Neuron Responsiveness to Sustained Input Experimental Neurology. Jan, 2014 | Pubmed ID: 24252178 Synthesis of Lipid Mediators During UVB-induced Inflammatory Hyperalgesia in Rats and Mice PloS One. 2013 | Pubmed ID: 24349046 Probing Functional Properties of Nociceptive Axons Using a Microfluidic Culture System PloS One. 2013 | Pubmed ID: 24278311 Chemokine Expression in Peripheral Tissues from the Monosodium Iodoacetate Model of Chronic Joint Pain Molecular Pain. 2013 | Pubmed ID: 24206615 A Microchannel Neuroprosthesis for Bladder Control After Spinal Cord Injury in Rat Science Translational Medicine. Nov, 2013 | Pubmed ID: 24197736 Chemokines As Peripheral Pain Mediators Neuroscience Letters. Dec, 2013 | Pubmed ID: 24120432 PainNetworks: a Web-based Resource for the Visualisation of Pain-related Genes in the Context of Their Network Associations Pain. Dec, 2013 | Pubmed ID: 24036287 Chronic Cough and Pain: Janus Faces in Sensory Neurobiology? Pulmonary Pharmacology & Therapeutics. Oct, 2013 | Pubmed ID: 23831712 Axonal Neuregulin 1 is a Rate Limiting but Not Essential Factor for Nerve Remyelination Brain : a Journal of Neurology. Jul, 2013 | Pubmed ID: 23801741 HDAC Inhibitors Attenuate the Development of Hypersensitivity in Models of Neuropathic Pain Pain. Sep, 2013 | Pubmed ID: 23693161 Characterisation and Mechanisms of Bradykinin-evoked Pain in Man Using Iontophoresis Pain. Jun, 2013 | Pubmed ID: 23422725 Genes and Epigenetic Processes As Prospective Pain Targets Genome Medicine. 2013 | Pubmed ID: 23409739 Genes Contributing to Pain Sensitivity in the Normal Population: an Exome Sequencing Study PLoS Genetics. 2012 | Pubmed ID: 23284290 Sensory Neuron Downregulation of the Kv9.1 Potassium Channel Subunit Mediates Neuropathic Pain Following Nerve Injury The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2012 | Pubmed ID: 23197740 Chondroitinase ABC Promotes Plasticity of Spinal Reflexes Following Peripheral Nerve Injury Experimental Neurology. Nov, 2012 | Pubmed ID: 22917776 Understanding Chronic Inflammatory and Neuropathic Pain Annals of the New York Academy of Sciences. May, 2012 | Pubmed ID: 22564068 Chronic Pain: Emerging Evidence for the Involvement of Epigenetics Neuron. Feb, 2012 | Pubmed ID: 22325197 A Regenerative Microchannel Neural Interface for Recording from and Stimulating Peripheral Axons in Vivo Journal of Neural Engineering. Feb, 2012 | Pubmed ID: 22258138 Conduction Failure Following Spinal Cord Injury: Functional and Anatomical Changes from Acute to Chronic Stages The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2011 | Pubmed ID: 22171053 Specific Involvement of Atypical PKCζ/PKMζ in Spinal Persistent Nociceptive Processing Following Peripheral Inflammation in Rat Molecular Pain. 2011 | Pubmed ID: 22054645 CXCL5 Mediates UVB Irradiation-induced Pain Science Translational Medicine. Jul, 2011 | Pubmed ID: 21734176 New Molecules for the Treatment of Pain Current Opinion in Supportive and Palliative Care. Jun, 2011 | Pubmed ID: 21455071 Perturbing PSD-95 Interactions with NR2B-subtype Receptors Attenuates Spinal Nociceptive Plasticity and Neuropathic Pain Molecular Therapy : the Journal of the American Society of Gene Therapy. Oct, 2011 | Pubmed ID: 21427709 Delayed Treatment with Chondroitinase ABC Reverses Chronic Atrophy of Rubrospinal Neurons Following Spinal Cord Injury Experimental Neurology. Mar, 2011 | Pubmed ID: 21215745 Systemic Blockade of P2X3 and P2X2/3 Receptors Attenuates Bone Cancer Pain Behaviour in Rats Brain : a Journal of Neurology. Sep, 2010 | Pubmed ID: 20802203 Cortical Overexpression of Neuronal Calcium Sensor-1 Induces Functional Plasticity in Spinal Cord Following Unilateral Pyramidal Tract Injury in Rat PLoS Biology. 2010 | Pubmed ID: 20585375 Ultraviolet-B-induced Mechanical Hyperalgesia: A Role for Peripheral Sensitisation Pain. Jul, 2010 | Pubmed ID: 20478657 Endogenous Purinergic Control of Bladder Activity Via Presynaptic P2X3 and P2X2/3 Receptors in the Spinal Cord The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2010 | Pubmed ID: 20335487 P2X7-dependent Release of Interleukin-1beta and Nociception in the Spinal Cord Following Lipopolysaccharide The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2010 | Pubmed ID: 20071520 Identification of Perineal Sensory Neurons Activated by Innocuous Heat The Journal of Comparative Neurology. Jan, 2010 | Pubmed ID: 19937707 Neural Progenitors Promote Axon Growth in Vitro and Ex Vivo but Not Following Injury Journal of Stem Cells. 2009 | Pubmed ID: 20498687 Current Challenges in Glia-pain Biology Neuron. Oct, 2009 | Pubmed ID: 19840548 Future Treatment Strategies for Neuropathic Pain Handbook of Experimental Pharmacology. 2009 | Pubmed ID: 19655119 Sensory Axon-derived Neuregulin-1 is Required for Axoglial Signaling and Normal Sensory Function but Not for Long-term Axon Maintenance The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2009 | Pubmed ID: 19535578 Microchannel Electrodes for Recording and Stimulation: in Vitro Evaluation IEEE Transactions on Bio-medical Engineering. May, 2009 | Pubmed ID: 19203882 Expression of the Regeneration-associated Protein SPRR1A in Primary Sensory Neurons and Spinal Cord of the Adult Mouse Following Peripheral and Central Injury The Journal of Comparative Neurology. Mar, 2009 | Pubmed ID: 19107756 Effects of Etanercept and Minocycline in a Rat Model of Spinal Cord Injury European Journal of Pain (London, England). Aug, 2009 | Pubmed ID: 18849175 Mice Lacking Acid-sensing Ion Channels (ASIC) 1 or 2, but Not ASIC3, Show Increased Pain Behaviour in the Formalin Test European Journal of Pain (London, England). Jul, 2009 | Pubmed ID: 18801682 Ultraviolet-B Induced Inflammation of Human Skin: Characterisation and Comparison with Traditional Models of Hyperalgesia European Journal of Pain (London, England). May, 2009 | Pubmed ID: 18691920 Comparison of Dorsal Root Ganglion Gene Expression in Rat Models of Traumatic and HIV-associated Neuropathic Pain European Journal of Pain (London, England). Apr, 2009 | Pubmed ID: 18606552 CCL2 is a Key Mediator of Microglia Activation in Neuropathic Pain States European Journal of Pain (London, England). Mar, 2009 | Pubmed ID: 18554968 The Yellow Fluorescent Protein (YFP-H) Mouse Reveals Neuroprotection As a Novel Mechanism Underlying Chondroitinase ABC-mediated Repair After Spinal Cord Injury The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2008 | Pubmed ID: 19109493 Chondroitinase ABC-mediated Plasticity of Spinal Sensory Function The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2008 | Pubmed ID: 19005065 Phosphatidylinositol 3-kinase is a Key Mediator of Central Sensitization in Painful Inflammatory Conditions The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2008 | Pubmed ID: 18417706 Microchannels As Axonal Amplifiers IEEE Transactions on Bio-medical Engineering. Mar, 2008 | Pubmed ID: 18334406 Modulation of Acid-sensing Ion Channel Activity by Nitric Oxide The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2007 | Pubmed ID: 18045919 Transplanted Neural Progenitor Cells Survive and Differentiate but Achieve Limited Functional Recovery in the Lesioned Adult Rat Spinal Cord Regenerative Medicine. Nov, 2007 | Pubmed ID: 18034631 Heritability of Responses to Painful Stimuli in Women: a Classical Twin Study Brain : a Journal of Neurology. Nov, 2007 | Pubmed ID: 17932101 Characterization of Rodent Models of HIV-gp120 and Anti-retroviral-associated Neuropathic Pain Brain : a Journal of Neurology. Oct, 2007 | Pubmed ID: 17761732 Pathophysiology of Peripheral Neuropathic Pain: Immune Cells and Molecules Anesthesia and Analgesia. Sep, 2007 | Pubmed ID: 17717248 The Activation of the ERK Pathway Contributes to the Spinal C-fos Expression Observed After Noxious Bladder Stimulation Somatosensory & Motor Research. Mar-Jun, 2007 | Pubmed ID: 17558919 Pharmacological, Behavioural and Mechanistic Analysis of HIV-1 Gp120 Induced Painful Neuropathy Pain. Dec, 2007 | Pubmed ID: 17433546 Role of Spinal Microglia in Rat Models of Peripheral Nerve Injury and Inflammation European Journal of Pain (London, England). Feb, 2007 | Pubmed ID: 16545974 Artemin Has Potent Neurotrophic Actions on Injured C-fibres Journal of the Peripheral Nervous System : JPNS. Dec, 2006 | Pubmed ID: 17117942 Nerve Injury Induces Robust Allodynia and Ectopic Discharges in Nav1.3 Null Mutant Mice Molecular Pain. 2006 | Pubmed ID: 17052333 Lentiviral Vector Expressing Retinoic Acid Receptor Beta2 Promotes Recovery of Function After Corticospinal Tract Injury in the Adult Rat Spinal Cord Human Molecular Genetics. Nov, 2006 | Pubmed ID: 16984961 Rapid Co-release of Interleukin 1beta and Caspase 1 in Spinal Cord Inflammation Journal of Neurochemistry. Nov, 2006 | Pubmed ID: 16942597 Spinal Cord Repair Strategies: Why Do They Work? Nature Reviews. Neuroscience. Aug, 2006 | Pubmed ID: 16858392 Neurotrophins: Mediators and Modulators of Pain Annual Review of Neuroscience. 2006 | Pubmed ID: 16776595 Increasingly Irritable and Close to Tears: TRPA1 in Inflammatory Pain Cell. Mar, 2006 | Pubmed ID: 16564004 Spinal ERK Activation Contributes to the Regulation of Bladder Function in Spinal Cord Injured Rats Experimental Neurology. Jul, 2006 | Pubmed ID: 16513110 Reversal of Neurochemical Changes and Pain-related Behavior in a Model of Neuropathic Pain Using Modified Lentiviral Vectors Expressing GDNF Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2006 | Pubmed ID: 16504588 A Clonal Cell Line from Immortalized Olfactory Ensheathing Glia Promotes Functional Recovery in the Injured Spinal Cord Molecular Therapy : the Journal of the American Society of Gene Therapy. Mar, 2006 | Pubmed ID: 16427362 ATF3 Expression in L4 Dorsal Root Ganglion Neurons After L5 Spinal Nerve Transection The European Journal of Neuroscience. Jan, 2006 | Pubmed ID: 16420444 Nociceptor-derived Brain-derived Neurotrophic Factor Regulates Acute and Inflammatory but Not Neuropathic Pain Molecular and Cellular Neurosciences. Mar, 2006 | Pubmed ID: 16413788 Retinoic Acid Receptor Beta2 Promotes Functional Regeneration of Sensory Axons in the Spinal Cord Nature Neuroscience. Feb, 2006 | Pubmed ID: 16388307 Assessing Behavioural Function Following a Pyramidotomy Lesion of the Corticospinal Tract in Adult Mice Experimental Neurology. Oct, 2005 | Pubmed ID: 16051217 Role of the Immune System in Chronic Pain Nature Reviews. Neuroscience. Jul, 2005 | Pubmed ID: 15995723 Inhibition of ERK Phosphorylation Decreases Nociceptive Behaviour in Monoarthritic Rats Pain. Aug, 2005 | Pubmed ID: 15979799 TrkB Expression and Phospho-ERK Activation by Brain-derived Neurotrophic Factor in Rat Spinothalamic Tract Neurons The Journal of Comparative Neurology. Aug, 2005 | Pubmed ID: 15977164 P2X2 Knockout Mice and P2X2/P2X3 Double Knockout Mice Reveal a Role for the P2X2 Receptor Subunit in Mediating Multiple Sensory Effects of ATP The Journal of Physiology. Sep, 2005 | Pubmed ID: 15961431 Activity-dependent Phosphorylation of Akt/PKB in Adult DRG Neurons The European Journal of Neuroscience. Apr, 2005 | Pubmed ID: 15869474 Immune and Glial Cell Factors As Pain Mediators and Modulators Experimental Neurology. Apr, 2005 | Pubmed ID: 15755561 Regulation of Neuropilin 1 by Spinal Cord Injury in Adult Rats Molecular and Cellular Neurosciences. Mar, 2005 | Pubmed ID: 15737738 Increased Spinal Cord Phosphorylation of Extracellular Signal-regulated Kinases Mediates Micturition Overactivity in Rats with Chronic Bladder Inflammation The European Journal of Neuroscience. Feb, 2005 | Pubmed ID: 15733095 Conditioning Injury-induced Spinal Axon Regeneration Requires Signal Transducer and Activator of Transcription 3 Activation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2005 | Pubmed ID: 15716400 Acid-induced Pain and Its Modulation in Humans The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2004 | Pubmed ID: 15574747 Neurotrophic Influences on Neuropathic Pain Novartis Foundation Symposium. 2004 | Pubmed ID: 15469045 Brain-derived Neurotrophic Factor Induces NMDA Receptor Subunit One Phosphorylation Via ERK and PKC in the Rat Spinal Cord The European Journal of Neuroscience. Oct, 2004 | Pubmed ID: 15379998 Plasticity of Pain Signaling: Role of Neurotrophic Factors Exemplified by Acid-induced Pain Journal of Neurobiology. Oct, 2004 | Pubmed ID: 15362154 Conditioning Injury-induced Spinal Axon Regeneration Fails in Interleukin-6 Knock-out Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2004 | Pubmed ID: 15128857 NGF and GDNF Ameliorate the Increase in ATF3 Expression Which Occurs in Dorsal Root Ganglion Cells in Response to Peripheral Nerve Injury The European Journal of Neuroscience. Mar, 2004 | Pubmed ID: 15066140 Ultraviolet Radiation-induced Inflammation As a Model for Cutaneous Hyperalgesia The Journal of Investigative Dermatology. Jan, 2004 | Pubmed ID: 14962107 Glial Cell Line-derived Neurotrophic Factor Increases Calcitonin Gene-related Peptide Immunoreactivity in Sensory and Motoneurons in Vivo The European Journal of Neuroscience. Nov, 2003 | Pubmed ID: 14656320 The Signaling Components of Sensory Fiber Transmission Involved in the Activation of ERK MAP Kinase in the Mouse Dorsal Horn Molecular and Cellular Neurosciences. Oct, 2003 | Pubmed ID: 14572451 EphB Receptors and Ephrin-B Ligands Regulate Spinal Sensory Connectivity and Modulate Pain Processing Nature Neuroscience. Apr, 2003 | Pubmed ID: 12640461 BDNF: a Neuromodulator in Nociceptive Pathways? Brain Research. Brain Research Reviews. Oct, 2002 | Pubmed ID: 12589922 Noxious Stimulation Induces Trk Receptor and Downstream ERK Phosphorylation in Spinal Dorsal Horn Molecular and Cellular Neurosciences. Dec, 2002 | Pubmed ID: 12504600 Molecular Forms of NGF in Human and Rat Neuropathic Tissues: Decreased NGF Precursor-like Immunoreactivity in Human Diabetic Skin Journal of the Peripheral Nervous System : JPNS. Sep, 2002 | Pubmed ID: 12365567 Chondroitinase ABC Promotes Functional Recovery After Spinal Cord Injury Nature. Apr, 2002 | Pubmed ID: 11948352 Neurotrophin-3-mediated Regeneration and Recovery of Proprioception Following Dorsal Rhizotomy Molecular and Cellular Neurosciences. Feb, 2002 | Pubmed ID: 11860276 P2X Receptors and Their Role in Female Idiopathic Detrusor Instability The Journal of Urology. Jan, 2002 | Pubmed ID: 11743296 Eenzijdige Pyramidotomy van de corticospinale Tract bij ratten voor de Beoordeling van neuroplasticiteits inducerende therapieën Claudia Kathe1, Thomas H. Hutson1, Qin Chen2, Harold D. Shine2, Stephen B. McMahon1, Lawrence D. F. Moon1 1Neurorestoration, Wolfson Centre for Age-Related Diseases, King's College London, 2Department of Neuroscience, Baylor College of Medicine JoVE 51843 Neuroscience
Eenzijdige Pyramidotomy van de corticospinale Tract bij ratten voor de Beoordeling van neuroplasticiteits inducerende therapieën Claudia Kathe1, Thomas H. Hutson1, Qin Chen2, Harold D. Shine2, Stephen B. McMahon1, Lawrence D. F. Moon1 1Neurorestoration, Wolfson Centre for Age-Related Diseases, King's College London, 2Department of Neuroscience, Baylor College of Medicine JoVE 51843 Neuroscience