Suzanne Jackowski Department of Infectious Diseases St. Jude Children's Research Hospital Biography Publications Institution JoVE Articles Suzanne Jackowski has not added a biography. If you are Suzanne Jackowski and would like to personalize this page please email our Author Liaison for assistance. Publications Antimalarial Pantothenamide Metabolites Target Acetyl-coenzyme A Biosynthesis in Science Translational Medicine. Sep, 2019 | Pubmed ID: 31534021 Proposed Therapies for Pantothenate-Kinase-Associated Neurodegeneration Journal of Experimental Neuroscience. 2019 | Pubmed ID: 31205425 Human Pantothenate Kinase 4 is a Pseudo-pantothenate Kinase Protein Science : a Publication of the Protein Society. Jun, 2019 | Pubmed ID: 30927326 A Therapeutic Approach to Pantothenate Kinase Associated Neurodegeneration Nature Communications. 10, 2018 | Pubmed ID: 30352999 Excess Coenzyme A Reduces Skeletal Muscle Performance and Strength in Mice Overexpressing Human PANK2 Molecular Genetics and Metabolism. 04, 2017 | Pubmed ID: 28189602 T Cells Encountering Myeloid Cells Programmed for Amino Acid-dependent Immunosuppression Use Rictor/mTORC2 Protein for Proliferative Checkpoint Decisions The Journal of Biological Chemistry. Jan, 2017 | Pubmed ID: 27903651 Allosteric Regulation of Mammalian Pantothenate Kinase The Journal of Biological Chemistry. Oct, 2016 | Pubmed ID: 27555321 Correction of a Genetic Deficiency in Pantothenate Kinase 1 Using Phosphopantothenate Replacement Therapy Molecular Genetics and Metabolism. Dec, 2015 | Pubmed ID: 26549575 Induction of Neuron-Specific Degradation of Coenzyme A Models Pantothenate Kinase-Associated Neurodegeneration by Reducing Motor Coordination in Mice PloS One. 2015 | Pubmed ID: 26052948 The CDP-Ethanolamine Pathway Regulates Skeletal Muscle Diacylglycerol Content and Mitochondrial Biogenesis Without Altering Insulin Sensitivity Cell Metabolism. May, 2015 | Pubmed ID: 25955207 A High-throughput Screen Reveals New Small-molecule Activators and Inhibitors of Pantothenate Kinases Journal of Medicinal Chemistry. Feb, 2015 | Pubmed ID: 25569308 Deregulated Coenzyme A, Loss of Metabolic Flexibility and Diabetes Biochemical Society Transactions. Aug, 2014 | Pubmed ID: 25110012 Physiological Roles of the Pantothenate Kinases Biochemical Society Transactions. Aug, 2014 | Pubmed ID: 25109998 Coenzyme A and Its Derivatives: Renaissance of a Textbook Classic Biochemical Society Transactions. Aug, 2014 | Pubmed ID: 25109997 Pank1 Deletion in Leptin-deficient Mice Reduces Hyperglycaemia and Hyperinsulinaemia and Modifies Global Metabolism Without Affecting Insulin Resistance Diabetologia. Jul, 2014 | Pubmed ID: 24781151 Preface: Phospholipids and Phospholipid Metabolism Biochimica Et Biophysica Acta. Mar, 2013 | Pubmed ID: 23369660 Phosphatidylcholine and the CDP-choline Cycle Biochimica Et Biophysica Acta. Mar, 2013 | Pubmed ID: 23010477 포유류 Pantothenate Kinases 보험회사입니다 PloS One. 2012 | Pubmed ID: 23152917 Germline Deletion of Pantothenate Kinases 1 and 2 Reveals the Key Roles for CoA in Postnatal Metabolism PloS One. 2012 | Pubmed ID: 22815849 The Specialized Unfolded Protein Response of B Lymphocytes: ATF6α-independent Development of Antibody-secreting B Cells Molecular Immunology. Jul, 2012 | Pubmed ID: 22555069 Cancer-associated Isocitrate Dehydrogenase Mutations Inactivate NADPH-dependent Reductive Carboxylation The Journal of Biological Chemistry. Apr, 2012 | Pubmed ID: 22442146 UPR-Mediated Membrane Biogenesis in B Cells Biochemistry Research International. 2012 | Pubmed ID: 22110962 The Unfolded Protein Response Transducer IRE1α Prevents ER Stress-induced Hepatic Steatosis The EMBO Journal. Apr, 2011 | Pubmed ID: 21407177 Modulation of Pantothenate Kinase 3 Activity by Small Molecules That Interact with the Substrate/allosteric Regulatory Domain Chemistry & Biology. Aug, 2010 | Pubmed ID: 20797618 Pantothenate Kinase 1 is Required to Support the Metabolic Transition from the Fed to the Fasted State PloS One. Jun, 2010 | Pubmed ID: 20559429 Phosphatidylcholine Biosynthesis During Neuronal Differentiation and Its Role in Cell Fate Determination The Journal of Biological Chemistry. Aug, 2010 | Pubmed ID: 20525991 Pantothenate Kinase from the Thermoacidophilic Archaeon Picrophilus Torridus Journal of Bacteriology. Jan, 2010 | Pubmed ID: 19854913 Elimination of the CDP-ethanolamine Pathway Disrupts Hepatic Lipid Homeostasis The Journal of Biological Chemistry. Oct, 2009 | Pubmed ID: 19666474 ATF6alpha Induces XBP1-independent Expansion of the Endoplasmic Reticulum Journal of Cell Science. May, 2009 | Pubmed ID: 19420237 CTP:phosphocholine Cytidylyltransferase Alpha is Required for B-cell Proliferation and Class Switch Recombination The Journal of Biological Chemistry. Mar, 2009 | Pubmed ID: 19139091 Membrane Phospholipid Synthesis and Endoplasmic Reticulum Function Journal of Lipid Research. Apr, 2009 | Pubmed ID: 18952570 Cytokine Secretion Requires Phosphatidylcholine Synthesis The Journal of Cell Biology. Jun, 2008 | Pubmed ID: 18559668 Biosynthesis of Pantothenic Acid and Coenzyme A EcoSal Plus. Apr, 2007 | Pubmed ID: 26443589 Localization and Regulation of Mouse Pantothenate Kinase 2 FEBS Letters. Oct, 2007 | Pubmed ID: 17825826 Probucol Therapy Overcomes the Reproductive Defect in CTP: Phosphocholine Cytidylyltransferase Beta2 Knockout Mice Biochimica Et Biophysica Acta. Jul, 2007 | Pubmed ID: 17560827 Chemical Knockout of Pantothenate Kinase Reveals the Metabolic and Genetic Program Responsible for Hepatic Coenzyme A Homeostasis Chemistry & Biology. Mar, 2007 | Pubmed ID: 17379144 Structure of the Type III Pantothenate Kinase from Bacillus Anthracis at 2.0 A Resolution: Implications for Coenzyme A-dependent Redox Biology Biochemistry. Mar, 2007 | Pubmed ID: 17323930 Activation of Human Mitochondrial Pantothenate Kinase 2 by Palmitoylcarnitine Proceedings of the National Academy of Sciences of the United States of America. Jan, 2007 | Pubmed ID: 17242360 Phospholipid Biosynthesis Program Underlying Membrane Expansion During B-lymphocyte Differentiation The Journal of Biological Chemistry. Mar, 2007 | Pubmed ID: 17213195 Role of Phosphocholine Cytidylyltransferase Alpha in Lung Development Molecular and Cellular Biology. Feb, 2007 | Pubmed ID: 17130238 Placental Thrombosis and Spontaneous Fetal Death in Mice Deficient in Ethanolamine Kinase 2 The Journal of Biological Chemistry. Sep, 2006 | Pubmed ID: 16861741 Biochemical Properties of Human Pantothenate Kinase 2 Isoforms and Mutations Linked to Pantothenate Kinase-associated Neurodegeneration The Journal of Biological Chemistry. Jan, 2006 | Pubmed ID: 16272150 Feedback Regulation of Murine Pantothenate Kinase 3 by Coenzyme A and Coenzyme A Thioesters The Journal of Biological Chemistry. Sep, 2005 | Pubmed ID: 16040613 Coenzyme A: Back in Action Progress in Lipid Research. Mar-May, 2005 | Pubmed ID: 15893380 Early Embryonic Lethality in Mice with Targeted Deletion of the CTP:phosphocholine Cytidylyltransferase Alpha Gene (Pcyt1a) Molecular and Cellular Biology. Apr, 2005 | Pubmed ID: 15798219 A Pantothenate Kinase from Staphylococcus Aureus Refractory to Feedback Regulation by Coenzyme A The Journal of Biological Chemistry. Feb, 2005 | Pubmed ID: 15548531 CTP: Phosphocholine Cytidylyltransferase: Paving the Way from Gene to Membrane The Journal of Biological Chemistry. Jan, 2005 | Pubmed ID: 15536089 XBP1: a Link Between the Unfolded Protein Response, Lipid Biosynthesis, and Biogenesis of the Endoplasmic Reticulum The Journal of Cell Biology. Oct, 2004 | Pubmed ID: 15466483 Acyl Carrier Protein is a Cellular Target for the Antibacterial Action of the Pantothenamide Class of Pantothenate Antimetabolites The Journal of Biological Chemistry. Dec, 2004 | Pubmed ID: 15459190 Bacterial Inhibition of Phosphatidylcholine Synthesis Triggers Apoptosis in the Brain The Journal of Experimental Medicine. Jul, 2004 | Pubmed ID: 15238609 Disruption of CCTbeta2 Expression Leads to Gonadal Dysfunction Molecular and Cellular Biology. Jun, 2004 | Pubmed ID: 15143167 The Structure of the Pantothenate Kinase.ADP.pantothenate Ternary Complex Reveals the Relationship Between the Binding Sites for Substrate, Allosteric Regulator, and Antimetabolites The Journal of Biological Chemistry. Aug, 2004 | Pubmed ID: 15136582 PPARalpha Controls the Intracellular Coenzyme A Concentration Via Regulation of PANK1alpha Gene Expression Journal of Lipid Research. Jan, 2004 | Pubmed ID: 14523052 Gene Structure, Expression and Identification of a New CTP:phosphocholine Cytidylyltransferase Beta Isoform Biochimica Et Biophysica Acta. Jul, 2003 | Pubmed ID: 12842190 Role of Feedback Regulation of Pantothenate Kinase (CoaA) in Control of Coenzyme A Levels in Escherichia Coli Journal of Bacteriology. Jun, 2003 | Pubmed ID: 12754240 The Murine Pantothenate Kinase (Pank1) Gene Encodes Two Differentially Regulated Pantothenate Kinase Isozymes Gene. May, 2002 | Pubmed ID: 12095677 Forty Years of Bacterial Fatty Acid Synthesis Biochemical and Biophysical Research Communications. Apr, 2002 | Pubmed ID: 11969206 A Missense Mutation in the FabB (beta-ketoacyl-acyl Carrier Protein Synthase I) Gene Confers Tiolactomycin Resistance to Escherichia Coli Antimicrobial Agents and Chemotherapy. May, 2002 | Pubmed ID: 11959552 Structure and Mechanism of CTP:phosphocholine Cytidylyltransferase (LicC) from Streptococcus Pneumoniae The Journal of Biological Chemistry. Feb, 2002 | Pubmed ID: 11706035 The LicC Gene of Streptococcus Pneumoniae Encodes a CTP:phosphocholine Cytidylyltransferase Journal of Bacteriology. Aug, 2001 | Pubmed ID: 11466299 Modulation of CTP:phosphocholine Cytidylyltransferase by Membrane Curvature Elastic Stress Proceedings of the National Academy of Sciences of the United States of America. Aug, 2000 | Pubmed ID: 10908674 Activity of the Phosphatidylcholine Biosynthetic Pathway Modulates the Distribution of Fatty Acids into Glycerolipids in Proliferating Cells Biochimica Et Biophysica Acta. Jan, 2000 | Pubmed ID: 10666565 세포와 조직에서 코엔자임 A의 정량화 Matthew W. Frank1, Chitra Subramanian1, Charles O. Rock1, Suzanne Jackowski1 1Department of Infectious Diseases, St. Jude Children's Research Hospital JoVE 60182 Biochemistry
세포와 조직에서 코엔자임 A의 정량화 Matthew W. Frank1, Chitra Subramanian1, Charles O. Rock1, Suzanne Jackowski1 1Department of Infectious Diseases, St. Jude Children's Research Hospital JoVE 60182 Biochemistry