Tayyaba Hasan Wellman Center for Photomedicine Massachusetts General Hospital Harvard Medical School Biography Publications Institution JoVE Articles Tayyaba Hasan has not added a biography. If you are Tayyaba Hasan and would like to personalize this page please email our Author Liaison for assistance. Publications Epidermal Growth Factor Receptor-targeted Photosensitizer Selectively Inhibits EGFR Signaling and Induces Targeted Phototoxicity in Ovarian Cancer Cells Cancer Letters. Jan, 2012 | Pubmed ID: 22266098 In Vivo Quantification of Tumor Receptor Binding Potential with Dual-Reporter Molecular Imaging Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Dec, 2011 | Pubmed ID: 22203241 Verteporfin-based Photodynamic Therapy Overcomes Gemcitabine Insensitivity in a Panel of Pancreatic Cancer Cell Lines Lasers in Surgery and Medicine. Sep, 2011 | Pubmed ID: 22057484 Killing Hypoxic Cell Populations in a 3D Tumor Model with EtNBS-PDT PloS One. 2011 | Pubmed ID: 21876751 High Vascular Delivery of EGF, but Low Receptor Binding Rate Is Observed in AsPC-1 Tumors As Compared to Normal Pancreas Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Aug, 2011 | Pubmed ID: 21847690 Vitamin D3 Enhances the Apoptotic Response of Epithelial Tumors to Aminolevulinate-based Photodynamic Therapy Cancer Research. Sep, 2011 | Pubmed ID: 21807844 Targeting of Sebaceous Glands by δ-aminolevulinic Acid-based Photodynamic Therapy: An in Vivo Study Lasers in Surgery and Medicine. Jul, 2011 | Pubmed ID: 21674542 Vaccination with Photodynamic Therapy-treated Macrophages Induces Highly Suppressive T-regulatory Cells Photodermatology, Photoimmunology & Photomedicine. Apr, 2011 | Pubmed ID: 21392113 A Three-dimensional in Vitro Ovarian Cancer Coculture Model Using a High-throughput Cell Patterning Platform Biotechnology Journal. Feb, 2011 | Pubmed ID: 21298805 Polarization-sensitive Optical Frequency Domain Imaging Based on Unpolarized Light Optics Express. Jan, 2011 | Pubmed ID: 21263595 Comparative Split-face Study of 5-aminolevulinic Acid Photodynamic Therapy with Intense Pulsed Light for Photorejuvenation of Asian Skin The Journal of Dermatology. Dec, 2010 | Pubmed ID: 21083701 Synergistic Enhancement of Carboplatin Efficacy with Photodynamic Therapy in a Three-dimensional Model for Micrometastatic Ovarian Cancer Cancer Research. Nov, 2010 | Pubmed ID: 21062986 Quantitative Imaging Reveals Heterogeneous Growth Dynamics and Treatment-dependent Residual Tumor Distributions in a Three-dimensional Ovarian Cancer Model Journal of Biomedical Optics. Sep-Oct, 2010 | Pubmed ID: 21054077 Ki-67 As a Molecular Target for Therapy in an in Vitro Three-dimensional Model for Ovarian Cancer Cancer Research. Nov, 2010 | Pubmed ID: 21045152 Development and Applications of Photo-triggered Theranostic Agents Advanced Drug Delivery Reviews. Aug, 2010 | Pubmed ID: 20858520 Rapid Functional Definition of Extended Spectrum β-lactamase Activity in Bacterial Cultures Via Competitive Inhibition of Fluorescent Substrate Cleavage Photochemistry and Photobiology. Nov-Dec, 2010 | Pubmed ID: 20854415 Imaging Targeted-agent Binding in Vivo with Two Probes Journal of Biomedical Optics. May-Jun, 2010 | Pubmed ID: 20614996 The ABC's of Industry: a Postdoc Program Provides a Sneak Peek into Industry Careers Nature Biotechnology. Jun, 2010 | Pubmed ID: 20531344 System Development for High Frequency Ultrasound-guided Fluorescence Quantification of Skin Layers Journal of Biomedical Optics. Mar-Apr, 2010 | Pubmed ID: 20459273 Monitoring the Efficacy of Antimicrobial Photodynamic Therapy in a Murine Model of Cutaneous Leishmaniasis Using L. Major Expressing GFP Journal of Biophotonics. Jun, 2010 | Pubmed ID: 20376860 Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization Chemical Reviews. May, 2010 | Pubmed ID: 20353192 Diffusive and Directional Intracellular Dynamics Measured by Field-based Dynamic Light Scattering Optics Express. Feb, 2010 | Pubmed ID: 20174115 Imaging Tumor Variation in Response to Photodynamic Therapy in Pancreatic Cancer Xenograft Models International Journal of Radiation Oncology, Biology, Physics. Jan, 2010 | Pubmed ID: 20005458 Detecting Epidermal Growth Factor Receptor Tumor Activity in Vivo During Cetuximab Therapy of Murine Gliomas Academic Radiology. Jan, 2010 | Pubmed ID: 19796971 Enhanced Susceptibility to Leishmania Infection in Resistant Mice in the Absence of Immediate Early Response Gene X-1 Journal of Immunology (Baltimore, Md. : 1950). Dec, 2009 | Pubmed ID: 19923449 Optimization of Topical Photodynamic Therapy with 3,7-bis(di-n-butylamino)phenothiazin-5-ium Bromide for Cutaneous Leishmaniasis Lasers in Surgery and Medicine. Jul, 2009 | Pubmed ID: 19533767 In Vitro Ovarian Tumor Growth and Treatment Response Dynamics Visualized with Time-lapse OCT Imaging Optics Express. May, 2009 | Pubmed ID: 19466138 Low-dose Methotrexate Enhances Aminolevulinate-based Photodynamic Therapy in Skin Carcinoma Cells in Vitro and in Vivo Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2009 | Pubmed ID: 19447864 Diagnostic Detection of Diffuse Glioma Tumors in Vive with Molecular Fluorescent Probe-based Transmission Spectroscopy Medical Physics. Mar, 2009 | Pubmed ID: 19378758 Noninvasive Measurement of Aminolevulinic Acid-induced Protoporphyrin IX Fluorescence Allowing Detection of Murine Glioma in Vivo Journal of Biomedical Optics. Jan-Feb, 2009 | Pubmed ID: 19256695 Quantitative Imaging of Scattering Changes Associated with Epithelial Proliferation, Necrosis, and Fibrosis in Tumors Using Microsampling Reflectance Spectroscopy Journal of Biomedical Optics. Jan-Feb, 2009 | Pubmed ID: 19256692 Exploiting a Bacterial Drug-resistance Mechanism: a Light-activated Construct for the Destruction of MRSA Angewandte Chemie (International Ed. in English). 2009 | Pubmed ID: 19206126 Intracellular Drug Delivery by Poly(lactic-co-glycolic Acid) Nanoparticles, Revisited Molecular Pharmaceutics. Jan-Feb, 2009 | Pubmed ID: 19035785 Antimicrobial Photodynamic Efficacy of Side-chain Functionalized Benzo[a]phenothiazinium Dyes Photochemistry and Photobiology. Jan-Feb, 2009 | Pubmed ID: 18657053 Pulsed Diode Laser-based Singlet Oxygen Monitor for Photodynamic Therapy: in Vivo Studies of Tumor-laden Rats Journal of Biomedical Optics. Nov-Dec, 2008 | Pubmed ID: 19123681 In-vivo Singlet Oxygen Dosimetry of Clinical 5-aminolevulinic Acid Photodynamic Therapy Journal of Biomedical Optics. Sep-Oct, 2008 | Pubmed ID: 19021376 Decreased Metastatic Phenotype in Cells Resistant to Aminolevulinic Acid-photodynamic Therapy Cancer Letters. Nov, 2008 | Pubmed ID: 18662847 Pulsed Diode Laser-based Monitor for Singlet Molecular Oxygen Journal of Biomedical Optics. May-Jun, 2008 | Pubmed ID: 18601555 Protoporphyrin IX Fluorescence Photobleaching Increases with the Use of Fractionated Irradiation in the Esophagus Journal of Biomedical Optics. May-Jun, 2008 | Pubmed ID: 18601554 In Vivo Optical Molecular Imaging of Vascular Endothelial Growth Factor for Monitoring Cancer Treatment Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2008 | Pubmed ID: 18593993 Prospects for the Use of Differentiation-modulating Agents As Adjuvant of Photodynamic Therapy for Proliferative Dermatoses The Journal of Dermatology. Apr, 2008 | Pubmed ID: 18419676 Ablation of Leptin Signaling Disrupts the Establishment, Development, and Maintenance of Endometriosis-like Lesions in a Murine Model Endocrinology. Feb, 2008 | Pubmed ID: 17962343 Real-time Fluorescence Monitoring of Phenothiazinium Photosensitizers and Their Anti-mycobacterial Photodynamic Activity Against Mycobacterium Bovis BCG in in Vitro and in Vivo Models of Localized Infection Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology. Oct, 2007 | Pubmed ID: 17914486 Photodynamic Therapy for Cutaneous Leishmaniasis: the Effectiveness of Topical Phenothiaziniums in Parasite Eradication and Th1 Immune Response Stimulation Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology. Oct, 2007 | Pubmed ID: 17914480 Photochemistry and Photobiology. Sep-Oct, 2007 | Pubmed ID: 17880492 Peptide-induced Inflammatory Increase in Vascular Permeability Improves Photosensitizer Delivery and Intersubject Photodynamic Treatment Efficacy Radiation Research. Sep, 2007 | Pubmed ID: 17705632 T Helper Type 1 Cytokines and Keratinocyte Growth Factor Play a Critical Role in Pseudoepitheliomatous Hyperplasia Initiation During Cutaneous Leishmaniasis Archives of Dermatological Research. Sep, 2007 | Pubmed ID: 17643254 Parasiticidal Effect of Delta-aminolevulinic Acid-based Photodynamic Therapy for Cutaneous Leishmaniasis is Indirect and Mediated Through the Killing of the Host Cells Experimental Dermatology. Aug, 2007 | Pubmed ID: 17620092 Photobleaching-based Dosimetry Predicts Deposited Dose in ALA-PpIX PDT of Rodent Esophagus Photochemistry and Photobiology. May-Jun, 2007 | Pubmed ID: 17576383 Clinical Manifestations and Classification of Old World Cutaneous Leishmaniasis International Journal of Dermatology. Feb, 2007 | Pubmed ID: 17269962 A Mechanistic Study of Delta-aminolevulinic Acid-based Photodynamic Therapy for Cutaneous Leishmaniasis The Journal of Investigative Dermatology. Jun, 2007 | Pubmed ID: 17218937 Vitamin D Enhances ALA-induced Protoporphyrin IX Production and Photodynamic Cell Death in 3-D Organotypic Cultures of Keratinocytes The Journal of Investigative Dermatology. Apr, 2007 | Pubmed ID: 17068479 Tumor Vascular Area Correlates with Photosensitizer Uptake: Analysis of Verteporfin Microvascular Delivery in the Dunning Rat Prostate Tumor Photochemistry and Photobiology. Sep-Oct, 2006 | Pubmed ID: 17421078 Vascular and Cellular Targeting for Photodynamic Therapy Critical Reviews in Eukaryotic Gene Expression. 2006 | Pubmed ID: 17206921 A Mechanism-based Combination Therapy Reduces Local Tumor Growth and Metastasis in an Orthotopic Model of Prostate Cancer Cancer Research. Nov, 2006 | Pubmed ID: 17108133 The Role of Photosensitizer Molecular Charge and Structure on the Efficacy of Photodynamic Therapy Against Leishmania Parasites Chemistry & Biology. Aug, 2006 | Pubmed ID: 16931333 Tumor Cell Lines Resistant to ALA-mediated Photodynamic Therapy and Possible Tools to Target Surviving Cells International Journal of Oncology. Aug, 2006 | Pubmed ID: 16820882 Protoporphyrin IX Level Correlates with Number of Mitochondria, but Increase in Production Correlates with Tumor Cell Size Photochemistry and Photobiology. Sep-Oct, 2006 | Pubmed ID: 16771607 Mechanistic Investigation and Implications of Photodynamic Therapy Induction of Vascular Endothelial Growth Factor in Prostate Cancer Cancer Research. Jun, 2006 | Pubmed ID: 16740700 Targeted Photodynamic Therapy Lasers in Surgery and Medicine. Jun, 2006 | Pubmed ID: 16671102 Photoinactivation of Mycobacteria in Vitro and in a New Murine Model of Localized Mycobacterium Bovis BCG-induced Granulomatous Infection Antimicrobial Agents and Chemotherapy. May, 2006 | Pubmed ID: 16641456 Targeting of Sebocytes by Aminolevulinic Acid-dependent Photosensitization Photochemistry and Photobiology. Mar-Apr, 2006 | Pubmed ID: 16613498 Pretreatment Photosensitizer Dosimetry Reduces Variation in Tumor Response International Journal of Radiation Oncology, Biology, Physics. Mar, 2006 | Pubmed ID: 16504761 Tumor Vascular Permeabilization by Vascular-targeting Photosensitization: Effects, Mechanism, and Therapeutic Implications Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2006 | Pubmed ID: 16467106 Liposomal Delivery of Photosensitising Agents Expert Opinion on Drug Delivery. May, 2005 | Pubmed ID: 16296769 Synergism of Epidermal Growth Factor Receptor-targeted Immunotherapy with Photodynamic Treatment of Ovarian Cancer in Vivo Journal of the National Cancer Institute. Oct, 2005 | Pubmed ID: 16234565 Photodynamic Therapy for Staphylococcus Aureus Infected Burn Wounds in Mice Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology. Jul, 2005 | Pubmed ID: 15986057 Combining Vascular and Cellular Targeting Regimens Enhances the Efficacy of Photodynamic Therapy International Journal of Radiation Oncology, Biology, Physics. Mar, 2005 | Pubmed ID: 15752904 Photochemical Targeting of Epidermal Growth Factor Receptor: a Mechanistic Study Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2005 | Pubmed ID: 15746071 Effect of Tumor Host Microenvironment on Photodynamic Therapy in a Rat Prostate Tumor Model Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2005 | Pubmed ID: 15701861 In Vivo Flow Cytometry: a New Method for Enumerating Circulating Cancer Cells Cancer Research. Aug, 2004 | Pubmed ID: 15289300 Effects of Growth Phase and Extracellular Slime on Photodynamic Inactivation of Gram-positive Pathogenic Bacteria Antimicrobial Agents and Chemotherapy. Jun, 2004 | Pubmed ID: 15155218 Analysis of Effective Molecular Diffusion Rates for Verteporfin in Subcutaneous Versus Orthotopic Dunning Prostate Tumors Photochemistry and Photobiology. Apr, 2004 | Pubmed ID: 15137508 Targeted Photodynamic Therapy of Established Soft-tissue Infections in Mice Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology. May, 2004 | Pubmed ID: 15122362 Photodynamic Therapy: a New Antimicrobial Approach to Infectious Disease? Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology. May, 2004 | Pubmed ID: 15122361 Blood Flow Dynamics After Photodynamic Therapy with Verteporfin in the RIF-1 Tumor Radiation Research. Oct, 2003 | Pubmed ID: 12968929 Optical Monitoring and Treatment of Potentially Lethal Wound Infections in Vivo The Journal of Infectious Diseases. Jun, 2003 | Pubmed ID: 12751029 Targeting Cells That Overexpress the Epidermal Growth Factor Receptor with Polyethylene Glycolated BPD Verteporfin Photosensitizer Immunoconjugates Photochemistry and Photobiology. Apr, 2003 | Pubmed ID: 12733655 Photodynamic Therapy with Verteporfin in the Radiation-induced Fibrosarcoma-1 Tumor Causes Enhanced Radiation Sensitivity Cancer Research. Mar, 2003 | Pubmed ID: 12615718 Plasma Matrix Metalloproteinase 9 As Biomarker of Prostate Cancer Progression in Dunning (Copenhagen) Rats The Prostate. Feb, 2003 | Pubmed ID: 12518325 Polycationic Photosensitizer Conjugates: Effects of Chain Length and Gram Classification on the Photodynamic Inactivation of Bacteria The Journal of Antimicrobial Chemotherapy. Jun, 2002 | Pubmed ID: 12039886 Detection of Female Lower Genital Tract Dysplasia Using Orally Administered 5-aminolevulinic Acid Induced Protoporphyrin IX: a Preliminary Study Gynecologic Oncology. Apr, 2002 | Pubmed ID: 11925131 Photodynamic Treatment Has Chondroprotective Effects on Articular Cartilage Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Mar, 2002 | Pubmed ID: 11918303 Localization of Rose Bengal, Aluminum Phthalocyanine Tetrasulfonate, and Chlorin E6 in the Rabbit Eye Retina (Philadelphia, Pa.). Feb, 2002 | Pubmed ID: 11884881 Rapid Control of Wound Infections by Targeted Photodynamic Therapy Monitored by in Vivo Bioluminescence Imaging Photochemistry and Photobiology. Jan, 2002 | Pubmed ID: 11837327 PuraMatrix Инкапсуляция раковых клеток Adnan O. Abu-Yousif1, Imran Rizvi1,2, Conor L. Evans1, Jonathan P. Celli1, Tayyaba Hasan1,3 1Wellman Center for Photomedicine Massachusetts General Hospital, Harvard Medical School, 2Thayer School of Engineering, Dartmouth College, 3Department of Dermatology, Harvard Medical School JoVE 1692 Biology
PuraMatrix Инкапсуляция раковых клеток Adnan O. Abu-Yousif1, Imran Rizvi1,2, Conor L. Evans1, Jonathan P. Celli1, Tayyaba Hasan1,3 1Wellman Center for Photomedicine Massachusetts General Hospital, Harvard Medical School, 2Thayer School of Engineering, Dartmouth College, 3Department of Dermatology, Harvard Medical School JoVE 1692 Biology