Xiao-Yu Tian School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences Chinese University of Hong Kong Biography Publications Institution JoVE Articles Xiao-Yu Tian has not added a biography. If you are Xiao-Yu Tian and would like to personalize this page please email our Author Liaison for assistance. Publications Uncoupling Protein 2 in Cardiovascular Health and Disease Frontiers in Physiology. 2018 | Pubmed ID: 30116205 Regulatory T Cells Promote Apelin-Mediated Sprouting Angiogenesis in Type 2 Diabetes Cell Reports. Aug, 2018 | Pubmed ID: 30089270 Recent Advances in Managing Atherosclerosis Via Nanomedicine Small (Weinheim an Der Bergstrasse, Germany). Jan, 2018 | Pubmed ID: 29239134 Inhibition of MiR-92a Suppresses Oxidative Stress and Improves Endothelial Function by Upregulating Heme Oxygenase-1 in Db/db Mice Antioxidants & Redox Signaling. 02, 2018 | Pubmed ID: 28683566 Comprehensive Analysis of Acylcarnitine Species in Db/db Mouse Using a Novel Method of High-Resolution Parallel Reaction Monitoring Reveals Widespread Metabolic Dysfunction Induced by Diabetes Analytical Chemistry. Oct, 2017 | Pubmed ID: 28859482 Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells Stem Cell Reports. 03, 2017 | Pubmed ID: 28262545 Myeloid Deletion Increases Monocyte Recruitment and Worsens Atherosclerosis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 03, 2017 | Pubmed ID: 27927724 PPARδ Is Required for Exercise to Attenuate Endoplasmic Reticulum Stress and Endothelial Dysfunction in Diabetic Mice Diabetes. 02, 2017 | Pubmed ID: 27856609 Integrin-YAP/TAZ-JNK Cascade Mediates Atheroprotective Effect of Unidirectional Shear Flow Nature. Dec, 2016 | Pubmed ID: 27926730 Reactive Oxygen Species, Endoplasmic Reticulum Stress and Mitochondrial Dysfunction: The Link with Cardiac Arrhythmogenesis Frontiers in Physiology. 2016 | Pubmed ID: 27536244 Melamine Impairs Renal and Vascular Function in Rats Scientific Reports. 06, 2016 | Pubmed ID: 27324576 E-selectin-targeting Delivery of MicroRNAs by Microparticles Ameliorates Endothelial Inflammation and Atherosclerosis Scientific Reports. Mar, 2016 | Pubmed ID: 26956647 Bone Morphogenic Protein 4-Smad-Induced Upregulation of Platelet-Derived Growth Factor AA Impairs Endothelial Function Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2016 | Pubmed ID: 26769046 Chronic Black Tea Extract Consumption Improves Endothelial Function in Ovariectomized Rats European Journal of Nutrition. Aug, 2016 | Pubmed ID: 26276555 A Revisit on the Renin-angiotensin System in Cardiovascular Biology Trends in Cardiovascular Medicine. Apr, 2016 | Pubmed ID: 26212445 Black Tea Protects Against Hypertension-associated Endothelial Dysfunction Through Alleviation of Endoplasmic Reticulum Stress Scientific Reports. May, 2015 | Pubmed ID: 25976123 Upregulation of Angiotensin (1-7)-Mediated Signaling Preserves Endothelial Function Through Reducing Oxidative Stress in Diabetes Antioxidants & Redox Signaling. Oct, 2015 | Pubmed ID: 25867182 Unconjugated Bilirubin Mediates Heme Oxygenase-1-induced Vascular Benefits in Diabetic Mice Diabetes. May, 2015 | Pubmed ID: 25475440 The Peroxisome Proliferator-activated Receptors in Cardiovascular Diseases: Experimental Benefits and Clinical Challenges British Journal of Pharmacology. Dec, 2015 | Pubmed ID: 25438608 Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension Via Differential Regulation of ET-1 Receptors PPAR Research. 2014 | Pubmed ID: 24701204 Metformin Protects Endothelial Function in Diet-induced Obese Mice by Inhibition of Endoplasmic Reticulum Stress Through 5' Adenosine Monophosphate-activated Protein Kinase-peroxisome Proliferator-activated Receptor δ Pathway Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2014 | Pubmed ID: 24482374 Uncoupling Protein-2 Mediates DPP-4 Inhibitor-induced Restoration of Endothelial Function in Hypertension Through Reducing Oxidative Stress Antioxidants & Redox Signaling. Oct, 2014 | Pubmed ID: 24328731 Inhibition of Bone Morphogenic Protein 4 Restores Endothelial Function in Db/db Diabetic Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2014 | Pubmed ID: 24202302 Pleiotropic Effects of Peroxisome Proliferator-activated Receptor γ and δ in Vascular Diseases Circulation Journal : Official Journal of the Japanese Circulation Society. 2013 | Pubmed ID: 24107399 Boldine Improves Endothelial Function in Diabetic Db/db Mice Through Inhibition of Angiotensin II-mediated BMP4-oxidative Stress Cascade British Journal of Pharmacology. Nov, 2013 | Pubmed ID: 23992296 Menthol Relaxes Rat Aortae, Mesenteric and Coronary Arteries by Inhibiting Calcium Influx European Journal of Pharmacology. Feb, 2013 | Pubmed ID: 23380688 Fo Shou San, an Ancient Chinese Herbal Decoction, Protects Endothelial Function Through Increasing Endothelial Nitric Oxide Synthase Activity PloS One. 2012 | Pubmed ID: 23284736 PPARδ-Aktivierung Schützt Endothelial Funktion Bei Diabetischen Mäusen Diabetes. Dec, 2012 | Pubmed ID: 22933110 Dipeptidyl Peptidase-4-Hemmer Sitagliptin Schützt Endothelial Funktion Bei Bluthochdruck Durch Glucagon-Like Peptid 1-abhängige Mechanismus Hypertension. Sep, 2012 | Pubmed ID: 22868389 Chronische Preiselbeersaft Verbrauch Stellt Cholesterin-Profile Und Verbessert Endothelial Funktion in Ovariectomized Ratten European Journal of Nutrition. Jul, 2012 | Pubmed ID: 22836513 Capsaicinoids Plasma-Cholesterin Senken Und Endothelial Funktion in Hamster Verbessern European Journal of Nutrition. Mar, 2012 | Pubmed ID: 22466858 NaHS Entspannt Ratte Hirnarterie In-vitro über Hemmung Des L-Typ Spannung-empfindlichen Ca(2+) Channel Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Feb, 2012 | Pubmed ID: 22133671 Knochen Morphogenen Protein-4 Induziert Endothelial Zelle Apoptosis Durch Oxidativen Stress-abhängige P38MAPK Und JNK Pathway Journal of Molecular and Cellular Cardiology. Jan, 2012 | Pubmed ID: 22064324 Raloxifen Verbessert Die Vaskuläre Reaktivität in Unter Druck Stehenden Septumdefekt Koronararterien Ovariectomized Hamsterpopulation Cholesterin Diät Gefüttert Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Feb, 2012 | Pubmed ID: 22005391 Oxidativer Stress-abhängige Cyclooxygenase-2 Abgeleitete Prostaglandin F(2α) Beeinträchtigt Endothelial Funktion Renovascular Hypertensive Ratten Antioxidants & Redox Signaling. Feb, 2012 | Pubmed ID: 21951274 Endotheliale Stickstoffmonoxid-Synthase-Vergrößerer Reduziert Oxidativen Stress Und Endotheliale Funktion Bei Der Db/Db Maus Wiederhergestellt Cardiovascular Research. Nov, 2011 | Pubmed ID: 21875904 Adiponektin Ist Für PPARγ-vermittelte Verbesserung Der Endothelialen Funktion Bei Diabetischen Mäusen Erforderlich Cell Metabolism. Jul, 2011 | Pubmed ID: 21723508 Wirkung Von Phytosterinen Und Deren Oxidationsprodukten Auf Lipoprotein-Profile Und Vaskuläre Funktion in Zwerghamster Verfüttert Eine Hohe Cholesterin-Diät Atherosclerosis. Nov, 2011 | Pubmed ID: 21719014 Hemmung Des Renin-Angiotensin-Aldosteron-System Kehrt Endothelialen Dysfunktion Und Oxidativen Stress in Östrogen Unzulänglichen Ratten PloS One. 2011 | Pubmed ID: 21479266 AVE3085, Ein Vergrößerer Endotheliale Stickstoffmonoxid-Synthase, Endotheliale Funktion Wiederhergestellt Und Senkt Blutdruck Bei Spontan Hypertensive Ratten British Journal of Pharmacology. Jul, 2011 | Pubmed ID: 21385179 Telmisartan Hemmt Vasokonstriktion über PPARγ-abhängigen Ausdruck Und Aktivierung Der Endotheliale Stickstoffmonoxid-Synthase Cardiovascular Research. Apr, 2011 | Pubmed ID: 21156825 Prostaglandine in Aktion Unverzichtbare Rolle Der Cyclooxygenase-1 Und-2 Endothel-abhängige Muskelzuckungen Advances in Pharmacology (San Diego, Calif.). 2010 | Pubmed ID: 21081215 Knochen Morphogenen Protein-4 Beeinträchtigt Die Endotheliale Funktion Durch Oxidativen Stress-abhängige Cyclooxygenase-2 Hochregulation: Auswirkungen Auf Bluthochdruck Circulation Research. Oct, 2010 | Pubmed ID: 20724703 4-Pyridinamin-Sensitive K + Kanäle Trägt Zur NaHS-induzierte Membran Hyperpolarisation Und Entspannung in Der Ratte Koronare Herzkrankheit Vascular Pharmacology. Sep-Oct, 2010 | Pubmed ID: 20430111 Endothelialen Dysfunktion: Die Gemeinsame Folge in Diabetes Und Bluthochdruck Journal of Cardiovascular Pharmacology. Apr, 2010 | Pubmed ID: 20422734 Angiotensin II Typ-1-Rezeptor-abhängige Oxidativer Stress Vermittelt Endothelialen Dysfunktion Bei Diabetischen Mäusen Typ 2 Antioxidants & Redox Signaling. Sep, 2010 | Pubmed ID: 20136508 Eine familiäre Hypercholesterinämie menschlichen Leber chimärer Maus-Modell mit induzierten pluripotenten Stammzellen gewonnenen Hepatozyten Jiayin Yang*1,2,6, Lai-Yung Wong*2, Xiao-Yu Tian*3, Rui Wei1,2, Wing-Hon Lai2, Ka-Wing Au2, Zhiwei Luo4,5, Carl Ward4,5, Wai-In Ho2, David P. Ibañez4,5, Hao Liu4,5, Xichen Bao4,5, Baoming Qin4,5, Yu Huang3, Miguel A. Esteban4,5,7, Hung-Fat Tse1,2,6,7 1Department of Medicine, University of Hong Kong-Shenzhen Hospital, 2The Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, 3School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, 4Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health and Guangzhou Medical University, 5Laboratory of RNA, Chromatin, and Human Disease, CAS Key Laboratory of Regenerative Biology and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 6Research Centre of Heart, Brain, Hormone, and Healthy Ageing, Li Ka Shing Faculty of Medicine, University of Hong Kong, 7Hong Kong-Guangdong Stem Cell and Regenerative Medicine Research Centre, University of Hong Kong and Guangzhou Institutes of Biomedicine and Health JoVE 57556 Developmental Biology
Eine familiäre Hypercholesterinämie menschlichen Leber chimärer Maus-Modell mit induzierten pluripotenten Stammzellen gewonnenen Hepatozyten Jiayin Yang*1,2,6, Lai-Yung Wong*2, Xiao-Yu Tian*3, Rui Wei1,2, Wing-Hon Lai2, Ka-Wing Au2, Zhiwei Luo4,5, Carl Ward4,5, Wai-In Ho2, David P. Ibañez4,5, Hao Liu4,5, Xichen Bao4,5, Baoming Qin4,5, Yu Huang3, Miguel A. Esteban4,5,7, Hung-Fat Tse1,2,6,7 1Department of Medicine, University of Hong Kong-Shenzhen Hospital, 2The Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, 3School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, 4Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health and Guangzhou Medical University, 5Laboratory of RNA, Chromatin, and Human Disease, CAS Key Laboratory of Regenerative Biology and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 6Research Centre of Heart, Brain, Hormone, and Healthy Ageing, Li Ka Shing Faculty of Medicine, University of Hong Kong, 7Hong Kong-Guangdong Stem Cell and Regenerative Medicine Research Centre, University of Hong Kong and Guangzhou Institutes of Biomedicine and Health JoVE 57556 Developmental Biology