Younsoo Bae Department of Pharmaceutical Sciences University of Kentucky Biography Publications Institution JoVE Articles Younsoo Bae has not added a biography. If you are Younsoo Bae and would like to personalize this page please email our Author Liaison for assistance. Publications In Vivo β-catenin Attenuation by the Integrin α5-targeting Nano-delivery Strategy Suppresses Triple Negative Breast Cancer Stemness and Metastasis Biomaterials. Jan, 2019 | Pubmed ID: 30352320 Colorectal Cancer Lung Metastasis Treatment with Polymer-drug Nanoparticles Journal of Controlled Release : Official Journal of the Controlled Release Society. 04, 2018 | Pubmed ID: 29421609 Leukemia Inhibitory Factor-Loaded Nanoparticles with Enhanced Cytokine Metabolic Stability and Anti-Inflammatory Activity Pharmaceutical Research. 01, 2018 | Pubmed ID: 29294201 Extracellular Vesicles Released by Cardiomyocytes in a Doxorubicin-Induced Cardiac Injury Mouse Model Contain Protein Biomarkers of Early Cardiac Injury Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 04, 2018 | Pubmed ID: 29070527 Development of Halofluorochromic Polymer Nanoassemblies for the Potential Detection of Liver Metastatic Colorectal Cancer Tumors Using Experimental and Computational Approaches Pharmaceutical Research. Nov, 2017 | Pubmed ID: 28840432 Polymer Nanoassemblies with Hydrophobic Pendant Groups in the Core Induce False Positive SiRNA Transfection in Luciferase Reporter Assays International Journal of Pharmaceutics. Aug, 2017 | Pubmed ID: 28629980 Polymer Micelle Formulation for the Proteasome Inhibitor Drug Carfilzomib: Anticancer Efficacy and Pharmacokinetic Studies in Mice PloS One. 2017 | Pubmed ID: 28273121 Comparison of Dialysis- and Solvatofluorochromism-Based Methods to Determine Drug Release Rates from Polymer Nanoassemblies Pharmaceutical Research. 02, 2017 | Pubmed ID: 27873146 Tethered Polymer Nanoassemblies for Sustained Carfilzomib Release and Prolonged Suppression of Proteasome Activity Therapeutic Delivery. 10, 2016 | Pubmed ID: 27790952 A Computational/Experimental Assessment of Antitumor Activity of Polymer Nanoassemblies for PH-Controlled Drug Delivery to Primary and Metastatic Tumors Pharmaceutical Research. 10, 2016 | Pubmed ID: 27356524 SOD1 Nanozyme with Reduced Toxicity and MPS Accumulation Journal of Controlled Release : Official Journal of the Controlled Release Society. 06, 2016 | Pubmed ID: 26928528 Polymer Nanoassemblies with Solvato- and Halo-fluorochromism for Drug Release Monitoring and Metastasis Imaging Therapeutic Delivery. 2015 | Pubmed ID: 26446432 Polymer Micelle Formulations of Proteasome Inhibitor Carfilzomib for Improved Metabolic Stability and Anticancer Efficacy in Human Multiple Myeloma and Lung Cancer Cell Lines The Journal of Pharmacology and Experimental Therapeutics. Nov, 2015 | Pubmed ID: 26311812 Release, Partitioning, and Conjugation Stability of Doxorubicin in Polymer Micelles Determined by Mechanistic Modeling Pharmaceutical Research. May, 2015 | Pubmed ID: 25407546 Alternating Magnetic Field-induced Hyperthermia Increases Iron Oxide Nanoparticle Cell Association/uptake and Flux in Blood-brain Barrier Models Pharmaceutical Research. May, 2015 | Pubmed ID: 25377069 Tumor-preferential Sustained Drug Release Enhances Antitumor Activity of Block Copolymer Micelles Journal of Drug Targeting. Aug, 2014 | Pubmed ID: 24766185 Photo-inducible Crosslinked Nanoassemblies for PH-controlled Drug Release Pharmaceutical Research. May, 2014 | Pubmed ID: 24254196 Block Copolymer Nanoassemblies for Photodynamic Therapy and Diagnosis Therapeutic Delivery. Nov, 2013 | Pubmed ID: 24228992 Synthesis and Characterization of PEG-iron Oxide Core-shell Composite Nanoparticles for Thermal Therapy Materials Science & Engineering. C, Materials for Biological Applications. Dec, 2013 | Pubmed ID: 24094173 Brushed Block Copolymer Micelles with PH-sensitive Pendant Groups for Controlled Drug Delivery Pharmaceutical Research. Aug, 2013 | Pubmed ID: 23636840 Semi-synthetic Mithramycin SA Derivatives with Improved Anticancer Activity Chemical Biology & Drug Design. May, 2013 | Pubmed ID: 23331575 Preference Toward a Polylysine Enantiomer in Inhibiting Prions Amino Acids. Mar, 2013 | Pubmed ID: 23179088 Block Copolymer Cross-linked Nanoassemblies Improve Particle Stability and Biocompatibility of Superparamagnetic Iron Oxide Nanoparticles Pharmaceutical Research. Feb, 2013 | Pubmed ID: 23080062 Pharmaceutical Differences Between Block Copolymer Self-assembled and Cross-linked Nanoassemblies As Carriers for Tunable Drug Release Pharmaceutical Research. Feb, 2013 | Pubmed ID: 23054094 Polymer Nanoparticulate Drug Delivery and Combination Cancer Therapy Future Oncology (London, England). Nov, 2012 | Pubmed ID: 23148619 Combination Effects of Docetaxel and Doxorubicin in Hormone-refractory Prostate Cancer Cells Biochemistry Research International. 2012 | Pubmed ID: 22811914 Les Propriétés Pharmacologiques De Polyéthylèneglycol-modified Bacillus Thiaminolyticus Thiaminase J'ai Enzyme The Journal of Pharmacology and Experimental Therapeutics. Jun, 2012 | Pubmed ID: 22431205 Drug Release Patterns and Cytotoxicity of PEG-poly(aspartate) Block Copolymer Micelles in Cancer Cells Pharmaceutical Research. Jul, 2012 | Pubmed ID: 22322898 Block Copolymer Micelles for Controlled Delivery of Glycolytic Enzyme Inhibitors Pharmaceutical Research. Mar, 2012 | Pubmed ID: 22033882 Degradable Cross-Linked Nanoassemblies As Drug Carriers for Heat Shock Protein 90 Inhibitor 17-N-Allylamino-17-demethoxy-geldanamycin Pharmaceuticals (Basel, Switzerland). Sep, 2011 | Pubmed ID: 27721325 Nanoparticulate Formulations of Mithramycin Analogs for Enhanced Cytotoxicity International Journal of Nanomedicine. 2011 | Pubmed ID: 22114504 Chaîne Linéaire Pégylé Recombinant Bacillus Thiaminolyticus Thiaminase J'ai Enzyme a Une Activité Inhibitrice Croissance Lignées De Cellules De La Leucémie Lymphoïde Molecular Cancer Therapeutics. Sep, 2011 | Pubmed ID: 21697396 Cross-linked Nanoassemblies from Poly(ethylene Glycol)-poly(aspartate) Block Copolymers As Stable Supramolecular Templates for Particulate Drug Delivery Biomacromolecules. Jul, 2011 | Pubmed ID: 21644544 A 3-in-1 Polymeric Micelle Nanocontainer for Poorly Water-soluble Drugs Molecular Pharmaceutics. Aug, 2011 | Pubmed ID: 21630670 Polymer Micelles with Hydrazone-ester Dual Linkers for Tunable Release of Dexamethasone Pharmaceutical Research. Oct, 2011 | Pubmed ID: 21614636 The Suppression of Prion Propagation Using Poly-L-lysine by Targeting Plasminogen That Stimulates Prion Protein Conversion Biomaterials. Apr, 2011 | Pubmed ID: 21288569 Polymer Nanoassemblies for Cancer Treatment and Imaging Therapeutic Delivery. Dec, 2010 | Pubmed ID: 22834015 Mixed PH-sensitive Polymeric Micelles for Combination Drug Delivery Pharmaceutical Research. Nov, 2010 | Pubmed ID: 20700632 Enhanced Stability of PEG-block-poly(N-hexyl Stearate L-aspartamide) Micelles in the Presence of Serum Proteins Molecular Pharmaceutics. Aug, 2010 | Pubmed ID: 20575526 PEG-poly(amino Acid) Block Copolymer Micelles for Tunable Drug Release Pharmaceutical Research. Nov, 2010 | Pubmed ID: 20372992 PH-sensitive Multi-PEGylated Block Copolymer As a Bioresponsive PDNA Delivery Vector Pharmaceutical Research. Nov, 2010 | Pubmed ID: 20300803 Polymeric Micelles for the PH-dependent Controlled, Continuous Low Dose Release of Paclitaxel Biomaterials. Mar, 2010 | Pubmed ID: 19959225 Intelligent Polymeric Micelles from Functional Poly(ethylene Glycol)-poly(amino Acid) Block Copolymers Advanced Drug Delivery Reviews. Aug, 2009 | Pubmed ID: 19422866 Lucifer Yellow - Un marqueur de perméabilité paracellulaire robuste dans un modèle cellulaire de la barrière de sang-cerveau humain Wanzhu Zhao1, Linjiang Han1, Younsoo Bae2, Devika S. Manickam1 1Department of Pharmaceutical, Administrative and Social Sciences, Duquesne University, 2Department of Pharmaceutical Sciences, University of Kentucky JoVE 58900 Bioengineering
Lucifer Yellow - Un marqueur de perméabilité paracellulaire robuste dans un modèle cellulaire de la barrière de sang-cerveau humain Wanzhu Zhao1, Linjiang Han1, Younsoo Bae2, Devika S. Manickam1 1Department of Pharmaceutical, Administrative and Social Sciences, Duquesne University, 2Department of Pharmaceutical Sciences, University of Kentucky JoVE 58900 Bioengineering