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General Laboratory Techniques

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Basic Methods in Cellular and Molecular Biology

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JoVE Behavior
JoVE Behavior documents observational and experimental techniques that seek to understand human and animal behavior. Work in this field includes analysis of genetic causes and physiological responses to internal or external stimuli as well as the implicated brain regions.
 JoVE Behavior

Assessing the Multiple Dimensions of Engagement to Characterize Learning: A Neurophysiological Perspective

1Department of Didactics, Université du Québec à Montréal, 2Department of IT and Tech3Lab, HEC Montreal, 3Department of Marketing and Tech3Lab, HEC Montreal, 4Department of Specialized Education, Université du Québec à Montréal


JoVE 52627

This paper aims to describe the techniques involved in the collection and synchronization of the multiple dimensions (behavioral, affective and cognitive) of learners’ engagement during a task.

 JoVE Behavior

Infant Auditory Processing and Event-related Brain Oscillations

1Center for Molecular & Behavioral Neuroscience, Rutgers University, State University of New Jersey, Newark, 2Department of Audiology, University of the Pacific, 3Department of Otolaryngology, Head & Neck Surgery, Stanford University


JoVE 52420

High-density electroencephalography (dEEG) is being used increasingly to study brain development and plasticity in the early years of life. Here we present an application of sophisticated analysis techniques that builds on traditional EEG recording to understand the oscillatory dynamics of rapid auditory processing in the infant brain.

 JoVE Behavior

Mindfulness in Motion (MIM): An Onsite Mindfulness Based Intervention (MBI) for Chronically High Stress Work Environments to Increase Resiliency and Work Engagement

1Department of Family Medicine, The Ohio State University College of Medicine, 2Critical Care Nursing, Wexner Medical Center, 3Department of Psychiatry, Stress, Trauma, and Resilience (STAR) Program, The Ohio State University College of Medicine


JoVE 52359

The Mindfulness in Motion (MIM) protocol offers a pragmatic Mindfulness Based Intervention (MBI) on-site, for persons working in chronically high-stress work environments that significantly increases resiliency and work engagement. The protocol has proven feasible, beneficial, and is easily adaptable to other high-stress workplaces.

 JoVE Behavior

Acquisition of a High-precision Skilled Forelimb Reaching Task in Rats

1Brain Research Institute, University of Zurich, 2Department of Biology and Department of Health Sciences and Technology, ETH Zurich, 3Clinical Neurorehabilitation, Department of Neurology, University of Zurich & University Hospital Zurich


JoVE 53010

A paradigm is presented to analyze the acquisition of a high-precision skilled forelimb reaching task in rats.

 JoVE Behavior

A Method for Remotely Silencing Neural Activity in Rodents During Discrete Phases of Learning

1Department of Neuroscience, Oberlin College


JoVE 52859

This protocol describes how to temporarily and remotely silence neuronal activity in discrete brain regions while rats are engaged in learning and memory tasks. The approach combines pharmacogenetics (Designer-Receptors-Exclusively-Activated-by-Designer-Drugs) with a behavioral paradigm (sensory preconditioning) that is designed to distinguish between different components of learning.

 JoVE Behavior

Morris Water Maze Test: Optimization for Mouse Strain and Testing Environment

1Department of Psychology, Behavioral Neuroscience, West Virginia University, 2Department of Physiology and Pharmacology, West Virginia University, 3Department of Neurology, N. Bud Grossman Center for Memory Research and Care, University of Minnesota, 4Department of Neuroscience, N. Bud Grossman Center for Memory Research and Care, University of Minnesota, 5GRECC, VA Medical Center, 6Center for Neuroscience, Center for Basic and Translational Stroke Research, West Virginia University


JoVE 52706

This manuscript describes a Morris water maze (MWM) protocol tailored for use with a commonly used mouse model of Alzheimer's disease. The MWM is widely used in transgenic mouse models. Implementation of a procedure sensitive to the background strain of the mouse model is essential for detecting group differences.

 JoVE Behavior

Simple and Computer-assisted Olfactory Testing for Mice

1Unit of Anatomy, Department of Medicine, University of Fribourg


JoVE 52944

We present a simple and unbiased olfactory test in mice. With this protocol olfactory discrimination, preference, avoidance and sensitivity to a novel odor as compared to water can be assessed in single behavioral sessions. This method is indicated for a single experimenter and analysis is based on computer-assisted video processing.

 JoVE Behavior

fMRI Validation of fNIRS Measurements During a Naturalistic Task

1Department of Psychiatry, Yale School of Medicine, 2Department of Electronics and Bioinformatics, Meiji University, 3Department of Histology and Neurobiology, Dokkyo Medical University School of Medicine, 4ADAM Center, Department of Physical Therapy, Movement and Rehabilitation Sciences, Northeastern University, 5Department of Neurobiology, Yale School of Medicine


JoVE 52116

We present a method to compare functional brain activity recorded during a naturalistic task using fNIRS with activity recorded during fMRI.

 JoVE Behavior

A Protocol for Housing Mice in an Enriched Environment

1Department of Molecular Virology, Immunology, and Medical Genetics, and Comprehensive Cancer Center, The Ohio State University


JoVE 52874

Environmental enrichment for mice requires a complex and challenging setup, as well as comprehensive husbandry and handling techniques to assure robust metabolic and anti-cancer effects in the mice. This protocol provides detailed procedures to reproduce the above mentioned effects in mice.

 JoVE Behavior

Quantifying Learning in Young Infants: Tracking Leg Actions During a Discovery-learning Task

1Division of Biokinesiology & Physical Therapy at the Herman Ostrow School of Dentistry, University of Southern California, 2Department of Kinesiology, Temple University, 3Department of Physical Therapy, Niigata University of Health and Welfare


JoVE 52841

A method is described in which 3-4 month old infants learn a task by discovery and their leg movements are captured to quantify the learning process.

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