The Journal of Visualized Experiments (JoVE) is a peer reviewed, PubMed-indexed video journal. Our mission is to increase the productivity of scientific research.

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Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (Intrahepatic cholestasis) or obstruction in large bile ducts (Extrahepatic cholestasis).
 JoVE Clinical and Translational Medicine

Creation of Reversible Cholestatic Rat Model


JoVE 2692 5/21/2011

Department of General Surgery, Providence Hospital and Medical Centers

Cholestasis is a clinical condition commonly encountered by both surgeons and gastroenterologists. Creation of a reversible cholestatic rat model can be challenging in view of the smaller size and unique hepatopancreatobiliary anatomy in rats. This video article demonstrates the creation of a reversible cholestatic model.

 JoVE Bioengineering

Tissue Engineering of the Intestine in a Murine Model


JoVE 4279 12/01/2012

Children's Hospital Los Angeles, Division of Pediatric Surgery, Saban Research Institute, Keck School of Medicine of the University of Southern California

This article and the accompanying video present our protocol for generating tissue-engineered intestine in the mouse, using an organoid units-on-scaffold approach.

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