Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Bioengineering / Directed Cellular Self-Assembly to Fabricate…
JoVE Journal
Bioengineering

This content is Open Access.

JoVE Journal Bioengineering
Directed Cellular Self-Assembly to Fabricate Cell-Derived Tissue Rings for Biomechanical Analysis and Tissue Engineering
Ultra-long Read Sequencing for Whole Genomic DNA Analysis
Journal (Bioengineering)
Ultra-long Read Sequencing for Whole Genomic DNA Analysis
Ratiometric Biosensors that Measure Mitochondrial Redox State and ATP in Living Yeast Cells
Journal (Bioengineering)
Ratiometric Biosensors that Measure Mitochondrial Redox State and ATP in Living Yeast Cells
 

Directed Cellular Self-Assembly to Fabricate Cell-Derived Tissue Rings for Biomechanical Analysis and Tissue Engineering

Article DOI: 10.3791/3366-v • 08:01 min • November 25th, 2011
November 25th, 2011 •
1, 1, 1, 1
1Biomedical Engineering Department, Worcester Polytechnic Institute

Chapters

Summary
Automatic Translation

This article outlines a versatile method to create cell-derived tissue rings by cellular self-assembly. Smooth muscle cells seeded into ring-shaped agarose wells aggregate and contract to form robust three-dimensional (3D) tissues within 7 days. Millimeter-scale tissue rings are conducive to mechanical testing and serve as building blocks for tissue assembly.

Tags

Directed Cellular Self-assembly Fabricate Cell-derived Tissue Rings Biomechanical Analysis Tissue Engineering Coronary Artery Bypass Surgery Autologous Donor Vessels Vascular Tissue Engineering Living Vascular Models Cell-based Methods Smooth Muscle Cells Agarose Wells Cohesive Tissue Ring Mechanical Analysis Physiological Analysis Biochemical Analysis Histological Analysis Ultimate Tensile Strength
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter