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Immunology and Infection

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JoVE Journal Immunology and Infection
Detecção de MicroRNAs em Microglia por PCR em tempo real no SNC normal e durante Neuroinflammation
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Detecção de MicroRNAs em Microglia por PCR em tempo real no SNC normal e durante Neuroinflammation

Article DOI: 10.3791/4097-v • 13:45 min • July 23rd, 2012
July 23rd, 2012 •
1, 1, 1, 1
1Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School

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Microglia residem macrófagos que fornecem a primeira linha de defesa e vigilância imune do sistema nervoso central. MicroRNAs são moléculas reguladoras, que desempenham um papel importante em muitos processos fisiológicos, incluindo a activação e diferenciação dos macrófagos. Neste artigo, descrevemos o método para a medição de microRNAs em microglia.

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Imunologia Neuroscience Genetics microglia macrófagos microRNA cérebro de camundongos PCR em tempo real neuroinflamação
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