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Journal / Immunology and Infection / Non invasiva Modello di neuropatogeno
JoVE Journal
Immunology and Infection

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Non invasiva Modello di neuropatogeno
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Non invasiva Modello di neuropatogeno

Article DOI: 10.3791/52018-v • 08:28 min • October 29th, 2014
October 29th, 2014 •
1, 1, 1, 2, 1
1School of Pharmacy, University College London, 2Mucin Biology Group, University of Gothenburg

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Qui, una procedura è descritta per la creazione di infezione sistemica nel ratto neonatale con colture di Escherichia coli K1. Questa procedura non invasiva consente colonizzazione del tratto gastrointestinale, traslocazione del patogeno alla circolazione sistemica, e l'invasione del sistema nervoso centrale al plesso coroide.

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Infezione Infezione batterica meningite batterica neonatale batteriemia sepsi modello animale polisaccaride K1 infezioni sistemiche tratto gastrointestinale di dipendenza
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