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Journal / Immunology and Infection / Gerando
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Immunology and Infection

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Isolation of Functional Cardiac Immune Cells
Journal (Immunology and Infection)
Isolation of Functional Cardiac Immune Cells
A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Journal (Immunology and Infection)
A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
 
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Gerando

Article DOI: 10.3791/54697-v • 08:48 min • October 25th, 2016
October 25th, 2016 •
1,2, *2, *2, 2, 1,2, 1,2, 2, 2, 1,2, 1,2
1Department of Immunology, University of Toronto, 2Princess Margaret Cancer Centre, University Health Network
* These authors contributed equally

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Descreve-se aqui um novo método para gerar receptores de células T específicas para o antigénio (TCR) por emparelhamento a TCRα ou TCRβ de um TCR existente, possuindo a especificidade do antigénio de interesse, com hemichain complementar do repertório do receptor de células T periféricas. Os TCRs gerados de novo manter-antigénio com especificidade uma afinidade variável.

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Immunology 116 Edição células T células apresentadoras de antigénio o receptor de células T hemichain transdução retroviral antigénio-especificidade humano clonagem
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