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Journal / Chemistry / 用于临床生产的正电子发射层析成像 (PET)…
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Chemistry

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JoVE Journal Chemistry
用于临床生产的正电子发射层析成像 (PET) 放射性同位素示踪合成协议的自动化
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用于临床生产的正电子发射层析成像 (PET) 放射性同位素示踪合成协议的自动化

Article DOI: 10.3791/58428-v • 10:20 min • October 26th, 2018
October 26th, 2018 •
*1, *2,3, 2,4, 1, 2,3, 2,4
1SOFIE, 2Department of Molecular & Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles (UCLA), 3Ahmanson Translational Imaging Division, University of California, Los Angeles (UCLA), 4Crump Institute for Molecular Imaging, University of California, Los Angeles (UCLA)
* These authors contributed equally

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参与多个早期临床研究试验的正电子发射断层扫描 (PET) 成像站点需要强大且多才多艺的放射性同位素示踪制造能力。以放射性同位素示踪 [18F] 克罗拉滨为例, 说明如何使用灵活、基于磁带的 radiosynthesizer 自动合成放射性同位素示踪, 并验证临床使用的合成。

Tags

化学 问题 140 正电子发射层析成像 自动化 radiosynthesis 临床验证 ELIXYS 克罗拉滨 临床应用 放射性同位素示踪
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