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JoVE Journal Cancer Research
CRISPR ベース Cas9 の競争の試金を使用して遺伝的依存関係の調査
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CRISPR ベース Cas9 の競争の試金を使用して遺伝的依存関係の調査

Article DOI: 10.3791/58710-v • 11:05 min • January 7th, 2019
January 7th, 2019 •
1, 1, 1, 1, 1, 2, 3, 1
1Tumor Initiation and Maintenance Program, Sanford Burnham Prebys Medical Discovery Institute, 2Blood Research Institute, Blood Center of Wisconsin, 3Department of Bioengineering, University of California, San Diego

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本稿では急性骨髄性白血病 (AML) 細胞増殖で複数の候補者の遺伝子の役割を簡単かつ迅速な捜査のためクラスター化定期的に空間短い回文を繰り返す (CRISPR) CRISPR ベース Cas9 方法を記述します。並列。この手法はスケーラブル、他癌細胞を同様に適用することができます。

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がん研究、問題 143、急性骨髄性白血病、CRISPR Cas9、高スループット試金、競争力のある成長の試金、DOT1L、白血病、がん
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