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Journal / Immunology and Infection / Enhanced Rabies Surveillance Using a Direct Rapid …
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
Enhanced Rabies Surveillance Using a Direct Rapid Immunohistochemical Test
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Enhanced Rabies Surveillance Using a Direct Rapid Immunohistochemical Test

Article DOI: 10.3791/59416-v • 08:58 min • April 30th, 2019
April 30th, 2019 •
1, 2, 3, 4, 4, 5
1Animal and Plant Health Inspection Service (APHIS), Wildlife Services, Knoxville, TN, United States Department of Agriculture (USDA), 2Animal and Plant Health Inspection Service (APHIS), Wildlife Services, Sutton, MA, United States Department of Agriculture (USDA), 3Animal and Plant Health Inspection Service (APHIS), Wildlife Services, Milton, FL, United States Department of Agriculture (USDA), 4Animal and Plant Health Inspection Service (APHIS), Wildlife Services, Concord, NH, United States Department of Agriculture (USDA), 5Lyssa LLC

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Summary
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The direct rapid immunohistochemical test (DRIT) offers a World Organization for Animal Health and World Health Organization (OIE/WHO) recognized alternative to the direct fluorescent antibody (DFA) test for rabies diagnosis. This test allows for field-based applications that can be performed in approximately 1 h upon brain impressions using light microscopy.

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Enhanced Rabies Surveillance Direct Rapid Immunohistochemical Test DRIT Decentralized Laboratories Electron Microscopy Simple Light Microscopy One Hour Results Economical Tool Rabies Diagnosis Rabies Surveillance Prevention And Control Programs Animal Collection Procedure Brainstem Samples
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