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JoVE Journal Cancer Research
Um modelo de rato resemcional ortotópico de câncer pancreático
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Um modelo de rato resemcional ortotópico de câncer pancreático

Article DOI: 10.3791/61726-v • 07:17 min • September 24th, 2020
September 24th, 2020 •
1,2,4,5, 1,2, 1,2, 1,2, 3, 1, 1,2, 1,2, 1,2
1Pancreatic Research Group, South Western Sydney Clinical School, University of New South Wales, 2Ingham Institute for Applied Medical Research, 3Centre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 4Surgical Innovations Unit, Westmead Hospital, 5Westmead Clinical School, University of Sydney

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No contexto clínico, pacientes com câncer pancreático localizado serão submetidos à pancreatectomia seguida de tratamento adjuvante. Este protocolo aqui relatado visa estabelecer um método seguro e eficaz de modelagem deste cenário clínico em camundongos nus, através da implantação ortotópica de câncer pancreático seguido de pancreatectomia distal e esplenectomia.

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Pesquisa do Câncer Questão 163 Adenocarcinoma ductal pancreático (PDAC) terapia adjuvante terapia neoadjuvante Pancreatectomia Modelo de camundongo ortotópico células estelares pancreáticas
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