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Modelo de oclusão traqueal fetal transuterina em camundongos
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Modelo de oclusão traqueal fetal transuterina em camundongos

Article DOI: 10.3791/61772-v • 06:31 min • February 5th, 2021
February 5th, 2021 •
1,2, 3, 1, 1, 3, 1
1The Center for Fetal, Cellular & Molecular Therapy, Cincinnati Fetal Center, Division of Pediatric General and Thoracic Surgery, Cincinnati Children’s Hospital Medical Center, 2Department of Pediatric Surgery, Tekirdag Namik Kemal University School of Medicine, 3The Division of Critical Care Medicine, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center

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Diversos modelos animais de hérnia diafragmática congênita e oclusão traqueal fetal apresentam vantagens e desvantagens em relação a questões éticas, custo, dificuldade cirúrgica, tamanho, taxas de sobrevivência e disponibilidade de ferramentas genéticas. Este modelo fornece uma nova ferramenta para estudar o impacto da oclusão traqueal e do aumento da pressão luminal no desenvolvimento pulmonar.

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Biologia do Desenvolvimento Edição 168 Oclusão Traqueal Fetal hérnia diafragmática congênita CAOS crescimento pulmonar desenvolvimento pulmonar fetal camundongos
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