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Journal / Neuroscience / Multiplexe Analyse der retinalen Genexpression…
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Neuroscience

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JoVE Journal Neuroscience
Multiplexe Analyse der retinalen Genexpression und der Chromatinzugänglichkeit mittels scRNA-seq und scATAC-seq
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Multiplexe Analyse der retinalen Genexpression und der Chromatinzugänglichkeit mittels scRNA-seq und scATAC-seq

Article DOI: 10.3791/62239-v • 06:24 min • March 12th, 2021
March 12th, 2021 •
*1, *1, 1, 1,2,3,4,5,6
1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital, 3Department of Ophthalmology, The Johns Hopkins Hospital, 4Department of Neurology, The Johns Hopkins Hospital, 5Institute for Cell Engineering, Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine
* These authors contributed equally

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Hier zeigen die Autoren den Nutzen von MULTI-seq für die Phänotypisierung und nachfolgende gepaarte scRNA-seq und scATAC-seq bei der Charakterisierung der transkriptomischen und chromatinischen Zugänglichkeitsprofile in der Netzhaut.

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Neuroscience Ausgabe 169 Entwicklung Krankheit scRNA-Seq scATAC-Seq MULTI-Seq Multiplex Chromatin
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