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JoVE Journal Behavior
Dyremodeller af depression - kronisk fortvivlelsesmodel (CDM)
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Dyremodeller af depression - kronisk fortvivlelsesmodel (CDM)

Article DOI: 10.3791/62579-v • 05:47 min • September 23rd, 2021
September 23rd, 2021 •
1,2, 3,4, 1,5
1Department of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 2Berta-Ottenstein-Programme for Clinician Scientists, Faculty of Medicine, University of Freiburg, 3Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives, 4Department of Stereotactic and Functional Neurosurgery, Medical Center - University Freiburg, Faculty of Medicine, University of Freiburg, 5Center for Basics in Neuromodulation, Faculty of Medicine, University of Freiburg

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Den kroniske fortvivlelsesmusemodel (CDM) af depression består af gentagne tvungne svømmesessioner og en anden forsinket svømmefase som udlæsning. Det repræsenterer en egnet model til induktion af en kronisk depressiv-lignende tilstand stabil i mindst 4 uger, der kan ændres til at evaluere subkroniske og akutte behandlingsinterventioner.

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