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Journal / Immunology and Infection / Makrofag differentiering og polarisering i en…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Makrofag differentiering og polarisering i en M2-lignende fænotype ved hjælp af en human monocyt-lignende THP-1 Leukæmi Cell Line
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Makrofag differentiering og polarisering i en M2-lignende fænotype ved hjælp af en human monocyt-lignende THP-1 Leukæmi Cell Line

Article DOI: 10.3791/62652-v • 06:38 min • August 2nd, 2021
August 2nd, 2021 •
1, 1, 1, 1, 1
1Price Institute of Surgical Research, Department of Surgery, University of Louisville

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M2-lignende tumor-associerede makrofager (TAM) er forbundet med tumor progression og dårlig prognose i kræft. Denne protokol fungerer som en detaljeret guide til reproducerer differentiere og polarisere THP-1 monocyt-lignende celler i M2-lignende makrofager inden for 14 dage. Denne model er grundlaget for at undersøge de antiinflammatoriske virkninger af TAM inden for tumormikromiljøet.

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Immunologi og infektion udgave 174
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