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Il modello di ratto 6-idrossidopamina della malattia di Parkinson
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Il modello di ratto 6-idrossidopamina della malattia di Parkinson

Article DOI: 10.3791/62923-v • 08:10 min • October 27th, 2021
October 27th, 2021 •
1, 1, 1, 1, 1, 1
1Department of Psychology, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo

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Il modello 6-idrossidopamina (6-OHDA) è stato utilizzato per decenni per far progredire la comprensione della malattia di Parkinson. In questo protocollo, dimostriamo come eseguire lesioni nigrostriatali unilaterali nel ratto iniettando 6-OHDA nel fascio proencefalico mediale, valutare i deficit motori e prevedere le lesioni utilizzando il test di stepping.

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Neuroscienze Numero 176
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