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Rating L-DOPA-induceret dyskinesier i den ensidigt 6-OHDA-læsionerede rottemodel af Parkinsons sygdom
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Rating L-DOPA-induceret dyskinesier i den ensidigt 6-OHDA-læsionerede rottemodel af Parkinsons sygdom

Article DOI: 10.3791/62924-v • 06:45 min • October 4th, 2021
October 4th, 2021 •
*1, *1, 1, 1
1Department of Psychology, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo
* These authors contributed equally

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Gnavermodeller af L-DOPA-inducerede dyskinesier er uvurderlige værktøjer til at identificere terapeutiske interventioner for at dæmpe udviklingen eller lindre de manifestationer, der opstår på grund af gentagen administration af L-DOPA. Denne protokol demonstrerer, hvordan man inducerer og analyserer dyskinetisk-lignende bevægelser i den ensidigt 6-OHDA-læsionerede rottemodel af Parkinsons sygdom.

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Biologi Udgave 176 Parkinsons sygdom basale ganglier 6-hydroxydopamin L-DOPA-induceret dyskinesier unormale ufrivillige bevægelser
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