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Journal / Immunology and Infection / Echtzeitüberwachung der mitochondrialen Atmung in …
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Immunology and Infection

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JoVE Journal Immunology and Infection
Echtzeitüberwachung der mitochondrialen Atmung in zytokindifferenzierten humanen primären T-Zellen
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Echtzeitüberwachung der mitochondrialen Atmung in zytokindifferenzierten humanen primären T-Zellen

Article DOI: 10.3791/62984-v • 06:55 min • October 19th, 2021
October 19th, 2021 •
*1, *1, 1, 1, 1,3, 2, 1
1National Center for Cancer Immune Therapy, Department of Oncology, University Hospital Herlev, 2Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, 3Department of Immunology and Microbiology, Inflammation and Cancer Group, University of Copenhagen
* These authors contributed equally

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Die metabolische Anpassung ist für T-Zellen von grundlegender Bedeutung, da sie Differenzierung, Persistenz und Zytotoxizität bestimmt. Hier wird ein optimiertes Protokoll zur Überwachung der mitochondrialen Atmung in ex vivo Zytokin-differenzierten humanen primären T-Zellen vorgestellt.

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