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JoVE Journal Cancer Research
Kultur af blærekræftorganoider som præcisionsmedicinske værktøjer
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Kultur af blærekræftorganoider som præcisionsmedicinske værktøjer

Article DOI: 10.3791/63192-v • 08:39 min • December 28th, 2021
December 28th, 2021 •
1,2,3,4, 1,2,3,4,5, 1,4, 1,4,5, 1,2, 1,2, 1,2,4, 1,2,3,4, 1,2,3, 1,2, 1,2, 1,2,3,4, *1,2,3,4,5, *1,2,3,4
1School of Biomedical Sciences, Faculty of Health, Queensland University of Technology (QUT) at Translational Research Institute, 2Queensland Bladder Cancer Initiative (QBCI), 3Centre for Personalised Analysis of Cancers (CPAC), 4Australian Prostate Cancer Research Centre - Queensland, 5Department of Urology, Princess Alexandra Hospital
* These authors contributed equally

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Patientafledte organoider (PDO'er) er et kraftfuldt værktøj i translationel kræftforskning, der afspejler både sygdommens genetiske og fænotypiske heterogenitet og respons på personlige kræftbehandlinger. Her er en konsolideret protokol til generering af humane primære blærekræft-PSO'er som forberedelse til evaluering af fænotypiske analyser og lægemiddelresponser detaljeret.

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Kræftforskning udgave 178
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