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Journal / Neuroscience / In vivo Positronemissietomografie om…
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JoVE Journal Neuroscience
In vivo Positronemissietomografie om activiteitspatronen te onthullen die worden geïnduceerd door diepe hersenstimulatie bij ratten
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In vivo Positronemissietomografie om activiteitspatronen te onthullen die worden geïnduceerd door diepe hersenstimulatie bij ratten

Article DOI: 10.3791/63478-v • 09:36 min • March 23rd, 2022
March 23rd, 2022 •
1, 2,3, 2,3, 1,2,3,4, 2,4,5
1Centro Nacional de Investigaciones Cardiovasculares (CNIC), 2Laboratorio de Imagen Médica, Instituto de Investigación Sanitaria Gregorio Marañón, 3Departamento de Bioingeniería e Ingeniería Aeroespacial, Universidad Carlos III de Madrid, 4CIBER de Salud Mental (CIBERSAM), 5High Performance Research Group in Physiopathology and Pharmacology of the Digestive System (NeuGut), Universidad Rey Juan Carlos

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We beschrijven een preklinische experimentele methode om metabole neuromodulatie geïnduceerd door acute diepe hersenstimulatie met in vivo FDG-PET te evalueren. Dit manuscript bevat alle experimentele stappen, van stereotaxische chirurgie tot de toepassing van de stimulatiebehandeling en de verwerving, verwerking en analyse van PET-beelden.

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Neurowetenschappen Nummer 181 stereotaxische chirurgie diepe hersenstimulatie positronemissietomografie [18F]-fluorodeoxyglucose neurostimulatie diermodellen
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