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Journal / Neuroscience / Transplantation af humant induceret pluripotent…
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Neuroscience

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JoVE Journal Neuroscience
Transplantation af humant induceret pluripotent stamcelleafledt mikroglia i immunkompetente mushjerne via ikke-invasiv transnasal vej
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Transplantation af humant induceret pluripotent stamcelleafledt mikroglia i immunkompetente mushjerne via ikke-invasiv transnasal vej

Article DOI: 10.3791/63574-v • 05:35 min • May 31st, 2022
May 31st, 2022 •
1,2, 1,2, 1,2, 1,2
1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi

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Protokollen, der præsenteres her, tillader transplantation af induceret pluripotent stamcelleafledt human microglia (iPSMG) i hjernen via en transnasal vej i immunkompetente mus. Fremgangsmåden til fremstilling og transnasal transplantation af celler og administration af cytokinblanding til opretholdelse af iPSMG er vist.

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Neurovidenskab udgave 183
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