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JoVE Journal Neuroscience
Full- versus subregion regional kvantifisering av Amyloid-Beta-belastning på musehjerneseseksjoner
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Full- versus subregion regional kvantifisering av Amyloid-Beta-belastning på musehjerneseseksjoner

Article DOI: 10.3791/63669-v • 07:28 min • May 19th, 2022
May 19th, 2022 •
1, 2, 3, 4, 4,5
1Henry E. Riggs School of Applied Life Sciences, Keck Graduate Institute, 2Crean College of Health and Behavioral Sciences, Chapman University, 3Keck Science Department, Claremont McKenna College, 4Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, 5Department of Neurology, University of California, Irvine

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Den nåværende protokollen beskriver og sammenligner prosedyren for å utføre en full-region eller sub-region av interesse analyse av sagittal mus hjerne seksjoner for å kvantifisere amyloid-beta belastning i APP / PS1 transgene musemodell av Alzheimers sykdom.

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