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JoVE Journal Neuroscience
En modell for epilepsi av infeksiøs etiologi ved bruk av Theilers Murine Encephalomyelitis Virus
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En modell for epilepsi av infeksiøs etiologi ved bruk av Theilers Murine Encephalomyelitis Virus

Article DOI: 10.3791/63673-v • 05:33 min • June 23rd, 2022
June 23rd, 2022 •
1, 1, 1,2, 3, 1,2, 3
1Department of Pharmacology and Toxicology, University of Utah, 2Interdepartmental Program in Neuroscience, University of Utah, 3Faculty of Veterinary Medicine, Institute of Pharmacology and Toxicology, Freie Universität Berlin

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Intracerebral infeksjon med Theilers murine encefalomyelittvirus (TMEV) i C57BL/6-mus replikerer mange av de tidlige og kroniske kliniske symptomene på viral encefalitt og påfølgende epilepsi hos mennesker. Denne artikkelen beskriver virusinfeksjon, symptomer og histopatologi for TMEV-modellen.

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