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Journal / Medicine / Hızlandırılmış Osteoartritin Medial Menisküs ve…
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JoVE Journal Medicine
Hızlandırılmış Osteoartritin Medial Menisküs ve Kıkırdak Çizik Murin Modelinin Destabilizasyonu
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Hızlandırılmış Osteoartritin Medial Menisküs ve Kıkırdak Çizik Murin Modelinin Destabilizasyonu

Article DOI: 10.3791/64159-v • 07:06 min • July 6th, 2022
July 6th, 2022 •
1, 1, 1, 2, 2
1Institute of Biomedical and Environmental Health Research, University of the West of Scotland, 2Institute of Infection, Immunity and Inflammation, University of Glasgow

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Mevcut protokol, medial miniskotibial ligamenti keserek fare dizinin dengesini bozduktan sonra eklem kıkırdağının yüzeyindeki kontrollü mikrobıçak çiziklerini tanımlamaktadır. Bu hayvan modeli, osteofit oluşumunu, osteosklerozu ve erken evre ağrıyı incelemek için uygun hızlandırılmış bir osteoartrit (OA) formu sunar.

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