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Journal / Immunology and Infection / 선천면역세포사멸을 평가하기 위한 카스파아제 활성화…
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
선천면역세포사멸을 평가하기 위한 카스파아제 활성화 평가
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선천면역세포사멸을 평가하기 위한 카스파아제 활성화 평가

Article DOI: 10.3791/64308-v • 10:23 min • January 20th, 2023
January 20th, 2023 •
1, 1, 1
1Department of Immunology, St. Jude Children's Research Hospital

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이 프로토콜은 시험관 내 및 생체 내 (마우스내) 감염, 무균 손상 및 암 모델 모두에 대한 반응으로 카스파제 활성화(카스파제-1, 카스파제-3, 카스파제-7, 카스파제-8, 카스파제-9 및 카스파제-11)를 평가하여 파이롭토시스, 세포자멸사, 괴사 및 PANoptosis와 같은 세포 사멸 경로의 개시를 결정합니다.

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면역학 및 감염 191호
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