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JoVE Journal Biology
Vurdering af de formodede antikryptokokegenskaber af rå og klarede ekstrakter fra bløddyr
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Vurdering af de formodede antikryptokokegenskaber af rå og klarede ekstrakter fra bløddyr

Article DOI: 10.3791/64540-v • 09:18 min • December 2nd, 2022
December 2nd, 2022 •
1, 1, 2, 1
1Molecular and Cellular Biology Department, University of Guelph, 2School of Environmental Sciences, University of Guelph

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Det humane svampepatogen Cryptococcus neoformans producerer en række virulensfaktorer (fx peptidaser) for at fremme dets overlevelse i værten. Miljønicher repræsenterer en lovende kilde til nye naturlige peptidasehæmmere. Denne protokol beskriver fremstillingen af ekstrakter fra bløddyr og vurderingen af deres virkning på produktionen af svampevirulensfaktor.

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Biologi udgave 190 Antifungal resistens antivirulens svampepatogenese peptidase peptidasehæmmere bløddyr
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